Browsing by Author "S.K. Mandal"

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Band structure of 85Sr
(2010) Suresh Kumar; S.K. Mandal; A.K. Jain; L. Chaturvedi; Rishi Kumar Sinha; Dinesh Negi; Ankul Dhal; R. Kumar; R.P. Singh; S. Muralithar; R.K. Bhowmik; S.C. Pancholi
High spin states in 85Sr were populated using the reaction 76Ge(13C, 4n) at a beam energy of 52 MeV. Gamma-gamma coincidence measurements along with investigation of directional correlation ratios were utilized to establish the extended level scheme upto I π=(35/2-). One of the positive parity states observed at 3383.3 keV ((Iπ=19/2(+)) may be considered as a magnetic rotational (ΔI=1) band, the negative parity states built on 3028.0 level show an irregular behaviour and does not exhibit magnetic rotation. © 2010 American Institute of Physics.
Differential gene expression analysis in antimony-unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarray
(2007) N. Singh; R. Almeida; H. Kothari; P. Kumar; G. Mandal; M. Chatterjee; S. Venkatachalam; M.K. Govind; S.K. Mandal; S. Sundar
In this study, cDNA microarray analysis of a closely related species, Leishmania major, was used as a screening tool to compare antimonial-resistant and susceptible clinical isolates of Leishmania donovani in order to to identify candidate genes on the basis of antimony resistance. Clinically confirmed resistant isolate 39 and sensitive isolate 2001 were used in this study. Many differentially regulated genes were identified whose expression levels differ in sodium antimony gluconate (SAG)-treated patients. Interestingly, genes on the array, showing changes in expression of over 2-fold revealed the identity of ABC transporters, which are known determinants of drug resistance in laboratory mutants. The functionality of the transporters was validated by flow cytometry which, being biologically informative, provides direct clues to gene function. The results suggest that isolate 39 could have developed resistance by an increased multidrug resistance protein (MRP)-like pump. This study provides preliminary clues to the role of a thiol-dependent efflux system in antimonial resistant clinical isolates of Leishmania donovani. © 2007 Cambridge University Press.
Dynamic analysis of a low speed high torque hydrostatic drive using steady-state characteristics
(2012) K. Dasgupta; S.K. Mandal; S. Pan
In this article dynamic analysis of an open-circuit hydrostatic (HST) drive has been carried out to study its performance. A Low Speed High Torque (LSHT) radial piston motor has been considered for the drive. Bondgraph simulation technique is used to model the hydrostatic drive. The relationships of the loss coefficients of the drive with the other system variables, obtained from the steady-state model, are identified through experimental investigation. Using the parametric values, the overall dynamic model of the hydrostatic drive has been validated experimentally. © 2011 Elsevier Ltd.
Indications of octupole correlation in 84Sr
(Institute of Physics, 2023) Anuj; S. Kumar; Naveen Kumar; Neelam Rajput; K. Rojeeta Devi; Neeraj Kumar; C.V. Ahmad; Akashrup Banerjee; Aman Rohilla; C.K. Gupta; Anand Pandey; Ravi Bhushan; Unnati Gupta; S.K. Mandal; S.S. Bhattacharjee; Divya Arora; R. Garg; Indu Bala; Rakesh Kumar; R.P. Singh; S. Muralithar; V.V. Jyothi; Chandrani Majumder; Hariprakash Sharma; Anupriya Sharma; S.K. Dhiman
Excited states in the 84Sr nucleus were investigated via the 76Ge(12C,4n)84Sr reaction at a beam energy of 58 MeV. The de-excited γ-rays were detected using the Indian National Gamma Array (INGA) spectrometer at Inter-University Accelerator Center, New Delhi. Directional Correlation from Oriented (DCO) states ratio and the polarization asymmetry (Δ) measurements were done to confirm the spin-parity of the low-lying states. Eight new γ-ray transitions were placed in the level scheme of 84Sr. The systematic behaviour of energy staggering S(I) of the γ-band (Band 1 and Band 2) was compared with the γ-bands in the mass A ≈ 80 region and the nuclei of other mass regions with similar behaviour (odd-I down). The E1 character is confirmed for strong γ-ray transitions connecting Band 3 to the Yrast band. Comparison of new results such as B(E1)/B(E2) ratio, frequency ratio ω −/ω + and energy displacement ΔE in 84Sr with those of 72Se, 150Sm, 152Gd, 220Ra and 224Th nuclei suggests the presence of octupole correlations in 84Sr. © 2023 IOP Publishing Ltd