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Browsing by Author "S.S. Yadav"

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    Activation of Toll-like receptors in meconium aspiration syndrome
    (Nature Publishing Group, 2018) V. Anand; S. Basu; S.S. Yadav; G. Narayan; B.D. Bhatia; A. Kumar
    Objective:Meconium aspiration syndrome (MAS) is a common cause of neonatal morbidity and mortality. Incomplete understanding of the pathogenesis of MAS has hindered the development of specific therapies. We hypothesized that activation of Toll-like receptors (TLRs) might play a role in the pathogenesis of MAS. The present study evaluated the expression of TLR 1, 4, 7, 8 and 9 in neonates with MAS.Study Design:The study included 39 neonates with MAS and 17 healthy gestational age-matched neonates as controls. Neonates with maternal chorioamnionitis, perinatal asphyxia, sepsis and congenital malformations were excluded. Good-quality total RNA from umbilical cord blood was reverse transcribed to prepare cDNA using Bio-Rad reverse transcription kit. This cDNA was used to study the expression status of TLR 1, 4, 7, 8 and 9 by real-time quantitative polymerase chain reaction.Results:Compared with controls, TLR1 and TLR4 were highly expressed, TLR9 was moderately expressed, TLR7 was weakly expressed and TLR8 expression was neutral in neonates with MAS. Within the MAS group, no difference in TLR expression was observed with respect to consistency of meconium, severity of the disease, oxygenation index and outcome.Conclusion:There is activation of TLRs in neonates with MAS. We speculate that these TLRs probably act as endogenous ligands for various components of meconium that initiate the inflammatory cascade of MAS and contribute to its pathogenesis. © 2018 Nature America, Inc., part of Springer Nature. All rights reserved.
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    Growth and productivity of groundnut (Arachis hypogaea l.) under varying levels and sources of sulphur in semi-arid conditions of Rajasthan
    (Agricultural Research Communication Centre, 2018) Nagesh Yadav; S.S. Yadav; Neelam Yadav; M.R. Yadav; Rakesh Kumar; L.R. Yadav; L.C. Yadav; O.P. Sharma
    A field experiment was conducted at Agronomy research farm, S.K.N. College of Agriculture, Jobner during kharif, 2015 in order to evaluate the performance of groundnut (Arachis hypogaea L.) under varying levels of sulphur and its sources. Results of experiment revealed that CGR of crop during 0 - 35 DAS registered significant increase upto application of sulphur at 45 kg/ha. However, at later stages of growth the significant increase was noted upto 60 kg S/ha only. Application of sulphur at 60 kg/ha recorded a significant increase of 6.1 per cent in RGR over 15 kg/ha during 70 DAS – at harvest stage. Likewise, application of 60 kg S/ha also significantly enhanced the number of total and effective nodules as well as fresh and dry weight of nodules/plant and produced significantly higher pod and biological yields of groundnut (1832 and 5361 kg/ha) than 45, 30 and 15 kg/ha. Application of sulphur through gypsum recorded significant increase in plant height and dry matter accumulation/m row length at all the stages of crop over SSP and elemental sulphur treatments. The maximum CGR at all the stages of crop was recorded when sulphur was applied through gypsum. Sulphur application through SSP registered 13.9, 9.8 and 21.4 per cent increase in CGR over elemental sulphur at these stages, respectively. On the other hand, SSP and gypsum increased the RGR by 7.2 and 6.3 per cent, respectively over elemental sulphur. Gypsum as a sources of sulphur fertilization recorded the highest number of 62.30 total and 55.00 effective nodules/plant and as well as fresh and dry weight of nodules (229.87 and 102.00 mg/plant) thereby increasing to the extent of 22.1, 27.6, 23.9 and 18.9 per cent over elemental sulphur. Sulphur application through gypsum produced 13.1 and 10.2 per cent higher pod and biological yield of groundnut over elemental sulphur. © 2018, Agricultural Research Communication Centre. All rights reserved.
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    Sulphur management in groundnut for higher productivity and profitability under semi-arid condition Of Rajasthan, India
    (Agricultural Research Communication Centre, 2019) Nagesh Yadav; S.S. Yadav; Neelam Yadav; M.R. Yadav; Rakesh Kumar; L.R. Yadav; V.K. Yadav; Arti Yadav
    The present study was planned to evaluate the performance of groundnut (Arachis hypogaea L.) under varying levels of sulphur and its sources under Semi-Arid condition of Rajasthan. Application of 60 kg S/ha resulted 8.8, 23.8 and 59.6% more pod/plant than 45, 30 and 15 kg S/ha, respectively. Gypsum as a source of S recorded 15.4 and 50.4% higher pods/ plant over SSP and elemental sulphur, respectively. However, number of kernels/pod increased significantly upto 45 kg/ha only. Gypsum and SSP improved the kernels/pod by 14.2 and 11.2% over elemental sulphur, respectively. Application of 60 kg S/ha resulted in 140, 345 and 744 kg/ha and 127, 319 and 616 kg/ha higher pod and kernel yield over 45, 30 and 15 kg/ha, respectively. Sulphur application through gypsum recorded the highest pod yield (1872 kg/ha) of groundnut that was 13.1 and 32.0 percent more than obtained under SSP and elemental sulphur treatment, respectively. Application of sulphur at 75 kg S/ha was recorded highest shelling% (72.13%) which were 7.0 and 10.9 per cent higher over 30 and 15 kg S/ha. The application of S at 45 kg/ha exhibited 7.6 and 17.0% higher protein content over 30 and 15 kg S/ha, respectively. Among sources, the highest protein content (23.75%), oil content (44.49%) and oil yield (597.76 kg/ha) was obtained with gypsum. Application of 60 kg S/ha increased oil yield by magnitude of 70.3, 175.1 and 316.9 kg/ha over 45, 30 and 15 kg S/ha, respectively. Sulphur application at the rate of 60 kg/ha increased the margin to the tune of 6343, 15867, 34062/ha over 45, 30 and 15 kg S/ha, respectively. Likewise, graded increment in levels of sulphur resulted in significantly higher BCR upto 60 kg/ha over lower levels. The maximum net returns (55358/ha) and BCR (1.68) were obtained with gypsum. © 2019, Agricultural Research Communication Centre. All rights reserved.
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