Browsing by Author "Sachin Kumar Jadhav"

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Comparative evaluation of pit & fissure sealant retention using cotton roll & rubber dam isolation techniques – a systematic review & meta-analysis
(Springer Nature, 2024) Neha Shukla; Zainab Akram; P. G. Naveen Kumar; Mahesh R. Khairnar; Sachin Kumar Jadhav; Savitha Priyadarsini
Background: Isolation with cotton rolls does not always provide as complete isolation as rubber dam, especially in procedures where absolute moisture control is critical. Therefore, this review aims to summarize and analyze previous studies evaluating the retention and marginal integrity of pit & fissure sealant using rubber dam and cotton roll isolation techniques during dental treatment in children. Material and methods: In accordance with PRISMA guidelines, search yielded 1361 articles, with seven RCTs and one non-RCT design meeting the inclusion criteria. Data were extracted on study design, sample size, sealant type, follow-up duration, retention rates, and caries incidence. Results: The comparison of retention rate between rubber dam and cotton roll at six months difference was non-significant (OR:1.15; p = 0.64) while there was significant difference at 12 month (OR:2.23; p < 0.001). The difference for the marginal integrity was statistically significant at six months (OR:2.00; p = 0.03) while non-significant difference observed (OR:1.74; p = 0.10) at 12 months. Conclusion: The sealant placed using a rubber dam as an isolation technique showed higher retention than the cotton roll after 12 months. In terms of marginal integrity, the performance of the rubber dam and cotton roll was equivalent at the end of 12 months. © The Author(s), under exclusive licence to British Dental Association 2024.
Comparison of platelet rich plasma and injectable steroids in the treatment of oral lichen planus: A systematic review and meta-analysis
(Wolters Kluwer Medknow Publications, 2025) Ajay Kumar; Adit Srivastava; Neha Sah; Amlendu Shekhar; Sivani Darjee; Saumya Shukla; Akhilesh Kumar Singh; Sachin Kumar Jadhav; Sonam Sah
Oral lichen planus (OLP) is the common acute or chronic, potentially malignant disorder of the oral mucosa. Steroids the primary treatment for OLP; however, their chemical composition often leads to significant side effects. Platelet-rich plasma (PRP), an autologous biologically active material has been explored as an alternative treatment option. This systematic review evaluates the effects of autologous platelet-rich plasma compared to injectable steroids for treatment of OLP. A comprehensive search for randomized controlled trials were conducted in PubMed, Web of Science, Google Scholar, and Scopus using search terms such as “oral lichen planus and corticosteroids and platelet rich plasma injection,” “oral lichen planus and corticosteroids,” “oral lichen planus and corticosteroids and PRP,” “oral lichen planus and PRP,” “OLP and PRP and steroid.” Articles selection followed the Preferred Reporting Items for Systematic Reviews and meta-analysis guidelines. A meta-analysis was performed to group studies and determine summary effect estimates. A total of nine Randomized Controlled Trials (RCT) involving 266OLP patients were included in the analysis. Both treatment methods demonstrated a statistically significant improvements in outcome parameters including lesion size, pain scores, and burning sensations from baseline to the end of treatment and during follow-up visits. Patients treated with autologous PRP reported lower levels of pain and burning sensations compared to those treated with corticosteroids. A significant difference was observed between the two treatments with PRP showing greater effectiveness in alleviating pain and burning sensation than injectable steroids. Both platelet-rich plasma and injectable steroids effectively reduce lesion size and pain in OLP patients as measured by the Visual Analog Scale (VAS). However, the difference in efficacy between the two treatments was not statistically significant. Nonetheless, platelet-rich plasma can be considered promising alternative treatment to injectable steroids. © 2025 National Journal of Maxillofacial Surgery.
Effect of Kangen and reverse osmosis water on dental plaque, salivary pH and salivary Streptococcus mutans counts: a randomized-controlled trial (A preliminary study)
(IWA Publishing, 2023) Ananta Kusumakar; Zainab Akram; Mahesh Ravindra Khairnar; Sachin Kumar Jadhav; Harloveen Sabharwal; Savitha S. Priyadarsini; Naveen P.G. Kumar
Purpose: The present randomized-controlled trial was conducted to assess the effect of Kangen water and reverse osmosis (RO) water on dental plaque, salivary pH and salivary Streptococcus mutans count. Materials and methods: This randomized control trial was conducted for 14 days on 24 randomly selected participants from the pool of undergraduate dental students. Participants were randomly divided into two groups of 12 each: the Kangen water (pH 9) group and the RO water group. Participants in each group were asked to drink allocated water for 7 days. Dental plaque, salivary pH and microbial colony-forming units (CFUs) were assessed after 7 and 14 days. Results: Intragroup comparison showed that all three outcomes showed a significant improvement in the Kangen water group after 14 days, whereas no difference was seen in the RO water group. Intergroup comparison showed a significant difference in plaque score and CFU among the two groups after 7 and 14 days, whereas pH between the two groups did not show a significant difference. Conclusions: Regular drinking of alkaline Kangen water with pH 9 was found to be effective in reducing plaque and salivary Streptococcus mutans count when compared to RO water. © 2023 The Authors
Effect of Laser Auricular Acupuncture in Tobacco Smoking Cessation: A Systematic Review and Meta-Analysis
(Mary Ann Liebert Inc., 2024) Zainab Akram; Mahesh R. Khairnar; P.G. Naveen Kumar; Sachin Kumar Jadhav; Ananta Kusumakar; S. Savitha Priyadarsini
Introduction: This study explores laser auricular acupuncture as a potential solution for nicotine dependence, comparing it to conventional counseling. With a death every 6.5 s due to tobacco, the systematic review aims to assess the efficacy of laser acupuncture versus counseling or placebo, offering insights into innovative strategies for combating tobacco addiction. Methods: A systematic search across scientific databases yielded 2537 articles (2000–2021), reduced to 1294 after deduplication. Abstract screening narrowed it down to eight articles; after a full-text assessment based on inclusion/exclusion criteria, four were selected. Inter-rater reliability between coders (Z.A., M.R.K.) was strong at each screening stage, with perfect agreement at the full text (j = 1.0), abstract (j = 0.99), and title (j = 0.89) stages, all with a 95% confidence interval. Results: In the meta-analysis of two studies on post-intervention nicotine dependence using the Fagerstrom scale, the laser group showed significantly lower scores (p = 0.002, mean difference = -0.60). Examining subjects who failed to quit smoking immediately after therapy, the laser group had 53.8% continuation compared to 83.0% in the comparison group (non-significant difference). At the 3-month mark, the continuation rates were 60.8% for the laser group and 86.6% for the comparison group (non-significant difference). Conclusion: Potential superiority of laser auricular acupuncture over behavioral counseling in tobacco cessation, with reported safety. However, the limited trials and sample size warrant cautious interpretation. Laser therapy emerges as a promising modality, but further extensive trials, especially in combination with other interventions, are crucial to solidify its efficacy in facilitating successful tobacco cessation. © Mary Ann Liebert, Inc.