Browsing by Author "Sakshi Gupta"

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A rare incidence and management of complex odontoma and surgical dehiscence in maxillary anterior region: A case report
(Wolters Kluwer Medknow Publications, 2023) Sakshi Gupta; Neelam Mittal; Thivya Shankari; Supriya Gupta
Odontoma is a benign odontogenic tumour, which is rather considered hamartoma. Hamartoma is not a true neoplasm, rather a growth of abnormal mixture of cells found in the body area they normally grows. Fully developed odontomas generally consist of enamel, dentin and pulpal tissues, in an unorganised manner. Some of them may contain cementum too. These are further grouped into compound and complex, depending on their clinical, radiographic and histologic features. Odontomas are generally asymptomatic and slow growing, but may cause bone expansion and hinderance in tooth eruption. These lesions are generally diagnosed by coincidence in radiograph. We are presenting a case and surgical management of complex odontoma and post‑operative dehiscence in the anterior right maxillary region of a 38‑year‑old male. © 2023 National Journal of Maxillofacial Surgery.
Assessment of pulp sensibility in the mature necrotic teeth using regenerative endodontic therapy with various scaffolds - Randomised clinical trial
(Wolters Kluwer Medknow Publications, 2021) Neelam Mittal; Harakh C. Baranwal; Praveen Kumar; Sakshi Gupta
Aim: This study aimed to evaluate and compare the possibility of regaining pulp sensibility and objectives of regeneration procedure in mature necrotic teeth using regenerative endodontics. Materials and Methods: A total of 36 mature necrotic teeth were selected and a regenerative endodontic procedure was performed. A total of four groups, each involving n = 9 teeth per group were randomly grouped as (1) periapical bleeding, (2) platelet-rich fibrin (PRF), (3) collagen, and (4) hydroxyapatite. Pulp testing and radiographic assessment of periapical healing (PH) were recorded at every 3-month interval for 1 year. Readings were compared as qualitative data using the Kruskal-Wallis test to see the inter-group significant difference. Results: Readings of pulp sensibility revealed non-significant results in all intervals. At 3 and 6 months, 22.3% in the PRF group and 11.15% in collagen group; and at 9 months, 44.4% in PRF group, 33.3% in the collagen group and 22.2% in hydroxyapatite group; and at 12-months, 66.6% in PRF, 44.4% in the collagen group, 33.3% in the hydroxyapatite group and 11.1% in the periapical bleeding group showed a positive response to the cold test. But all groups did not show a positive response to heat and electric pulp testing and showed good PH in all groups at the end of 12 months. Conclusions: The presence of sensibility to cold test is indicative of the formation of vital pulp-like tissues, which was the highest in the PRF group, followed by the collagen, hydroxyapatite and periapical bleeding groups. © 2021 Indian Journal of Dental Research Published by Wolters Kluwer - Medknow.
Comparative analysis of reduction in pain scores after single visit root canal treatment using endodontic irrigation protocols, namely, Conventional needle irrigation, PUI, PIPS and SWEEPS: A randomized control trial
(Wolters Kluwer Medknow Publications, 2023) Neelam Mittal; Harakh Chand Baranwal; Sakshi Gupta; Thivya Shankari; Supriya Gupta; Shubham Kharat
Introduction: To assess the effects of different irrigation activation systems on postoperative pain using a Visual Analog Scale (VAS), using new laser irrigation activation system shock wave-enhanced emission photoacoustic streaming (SWEEPS), photon-induced photoacoustic streaming (PIPS), passive ultrasonic irrigation activation techniques, compared with the conventional irrigation (CI) method. Materials and Methods: Sixty patients suffering from symptomatic irreversible pulpitis in maxillary or mandibular molars were enrolled and randomly assigned to four different irrigation activation groups (n = 15) after chemomechanical root canal preparation. Preoperative and postoperative pain scores were recorded using VAS. The data were collected and subjected to statistical analysis using IBM SPSS 20.0 software at a level of significance being 0.05. Results: We observed that mean pain scores decreased with time in all patients in all groups. The decrease in pain score was found to be statistically significant (P < 0.05) among both the genders in Group 3 (PIPS) and Group 4 (SWEEPS). Postoperatively, pain scores decreased significantly using Group 4 (SWEEPS), followed by Group 3 (PIPS), Group 2 (ultrasonic activation), and Group 1 (conventional needle irrigation). No significant relation was observed statistically between pain scores and age groups among all groups, except for preoperative score in Group 3 and age groups. Conclusion: Postoperative scores were lower in laser-activated irrigation systems as compared to the other activation systems. The highest pain scores were observed in case of CI method, at pre- and post-operative periods. © 2023 Journal of Conservative Dentistry | Published by Wolters Kluwer - Medknow .
Comparative evaluation of bioglass nanofiber, dexamethasone-coated bioglass nanofiber, and platelet-rich fibrin, as scaffolds in regenerative endodontic treatment of immature necrotic teeth: A randomized controlled trial
(Wolters Kluwer Medknow Publications, 2022) Sakshi Gupta; Neelam Mittal; Harakh Chand Baranwal; Chandana Rath; Thivya Shankari; Supriya Gupta
Aim: The aim of this study was to evaluate and compare the regenerative endodontic potential of dexamethasone-coated bioglass nanofiber (Dex-BGnf), bioglass nanofiber (BGnf), and platelet-rich fibrin (PRF) for inducing regeneration in necrotic immature permanent teeth. Materials and Methods: A total of 36 (n = 12) immature necrotic teeth with or without evidence of periapical lesion were included in the study. Patients were randomly allocated into three groups, based on the scaffolds used: Group I (PRF), II (BGnf), and III (Dex-BGnf). The clinical (electric pulp test) and radiographic evaluations (percentage increase in apical diameter, root length, root dentin thickness, and periapical healing) were compared at 6 and 12 months after the procedure with baseline records. Statistical Analysis: One-way ANOVA, post hoc Tukey analysis, and Kruskal-Wallis test were used for evaluating the data. A 6- and 12-month improvement analysis was done using paired t-test and Friedman test. Results: Clinically, all the 36 teeth were asymptomatic, but none gave a positive response to Electric Pulp Test (EPT) in time interval of 12 months. Dex-BGnf showed a statistically significant improvement in terms of increase in root length (P = 0.020) and root dentinal thickness (P = 0.001) when compared to PRF after 12 months. Conclusion: The study has shown that Dex-BGnf yielded significantly better results than PRF for inducing apexogenesis in necrotic immature teeth. © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
Comparative evaluation of resin-based sealers and bioceramic sealers for postoperative pain after endodontic treatment: A systematic review
(Wroclaw University of Medicine, 2024) Neelam Mittal; Thivyashankari Thangamuthu; Supriya Gupta; Sakshi Gupta; Harshitaa Aggarwal; Shubham Kharat
The systematic review aimed to compare and evaluate the effect of resin-based sealers and bioceramic sealers on postoperative pain after endodontic treatment. Two reviewers independently conducted electronic search in PubMed, the Web of Science, ScienceDirect, the Wiley Online Library, SpringerLink, Google Scholar, and the Cochrane Library, employing a complete dual-review process to ensure the inclusion of all relevant studies in the review. The search was carried out until November 2021. After selecting eligible studies, the risk of bias assessment was carried out using the revised Cochrane risk-of-bias tool for randomized trials (RoB 2). A total of 1,931 studies were identified from the electronic search, and finally 10 studies were included after full-text assessment. In all our included studies, the visual analog scale (VAS) was used for recording pain scores. Most of the studies recorded pain intensity starting from 6 h to 7 days. The results showed that there was no significant difference between resin-based sealers and bioceramic sealers in terms of incidence or intensity of postoperative pain at any point in time. © 2024, Wroclaw University of Medicine. All rights reserved.
Integrated mineral identification of PM10 using XRD, ATR-FTIR and SEM–EDX techniques in Indo-Gangetic Plain (IGP) and Indo-Himalayan Region (IHR)
(Springer Science and Business Media Deutschland GmbH, 2025) Preeti Tiwari; Sakshi Gupta; Shobhna Shankar; Priyanka Srivastava; Bharat Ji Mehrotra; Manoj Kumar Srivastava; Manish Naja; Ranu Gadi; Manoj C.Anil Kumar; Anit Dawar; Sudhir Kumar Sharma
The study examines the mineralogical, morphological and elemental characteristics of particulate matter (PM10) across the Indo-Gangetic Plain (Delhi and Varanasi) and the Indo-Himalayan region (Nainital) from January to December 2022. PM10 concentrations showed significant spatial variability, with average loading of 204 ± 86 μg m−3 in Delhi, 197 ± 87 μg m−3 in Varanasi and 68 ± 54 μg m−3 in Nainital. Advanced analytical techniques, including XRD, ATR-FTIR and SEM–EDX, were used for comprehensive characterization of PM10. The dominant minerals were identified in PM10 samples including quartz, dolomite, calcite, albite, illite, montmorillonite and hematite. Geogenic minerals (e.g. quartz, dolomite, and albite) were attributed to natural sources such as rock weathering and dust storms, while anthropogenic contributions (e.g. construction and industrial emissions) were associated with minerals like illite, montmorillonite and hematite. Elemental analysis of PM10 revealed Si and Al as the most abundant elements, along with Ca, Fe, K, Mg and others at the study sites. ATR-FTIR confirmed the evidence of both inorganic ions (e.g. SO42−, NO3− and NH4+) and organic functional groups, indicating mixed pollution sources. Morphological analysis further distinguished between irregular, geogenic particles, and spherical anthropogenic ones. This study also reveals that Delhi and Varanasi experience high anthropogenic pollution from industrial, vehicular and combustion sources, posing significant health risks from toxic elements like Cr, As and Pb. In contrast, Nainital is primarily influenced by natural sources, but episodic long-range pollutant transport also contributes to health risks, particularly from Mn. Air-mass backward trajectory analysis confirms cross-regional pollution transport, especially from the IGP and surrounding areas. These findings offer key understanding of the composition and origin of PM10, providing a scientific basis for improved air quality management in the region. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2025.
Management of Cracked Maxillary First Molar with Erbium‑Doped Yttrium Aluminum Garnet Laser
(Wolters Kluwer Medknow Publications, 2022) Neelam Mittal; Supriya Gupta; Sakshi Gupta; Thivya Shankari
Treatment and diagnosis of fractured teeth present a big challenge to dentists. Treatment of traumatized teeth can be done with reattachment of a dental fragment both in simple and complicated coronal fractures. A 28-year-old male patient came to our department with a traumatic crown fracture of the permanent, left maxillary molar. The patient complained of pain upon mastication, and on examination left maxillary second molar has a fracture line extending in a mesiodistal direction. Partial pulpotomy with the help of erbium-doped yttrium aluminum garnet (Er: YAG) laser was done to relieve symptoms and to reduce microleakage and increase strength, the fracture line was sealed with the help of Er: YAG laser. The cavity was then sealed with biodentin and composite. For these types of cases, Er: YAG laser is used for biostimulation of exposed pulp, and also to improve strength and reduce microleakage through sealing of fracture line. © 2022 Journal of Interdisciplinary Dentistry.
Unveiling the elemental composition, sources and health impacts of PM10 over the central Indo-Gangetic plain (IGP) of India
(Elsevier Ltd, 2024) Preeti Tiwari; Bharat Ji Mehrotra; Sakshi Gupta; Manoj K. Srivastava; Manoj Kumar; Narayanasamy Vijayan; Arti Choudhary; Sudhir Kumar Sharma
This study investigates the PM10 pollution in the central Indo−Gangetic plain (IGP) of India from February 2018 to December 2019, revealing an annual average PM10 concentration of 193±65 μg m−³. Seasonal concentrations peaked in winter season followed by summer, post-monsoon and monsoon seasons. WD−XRF identifying 35 elements, including major elements like Si, Al, Ca, and Fe, which contributed 18% to PM10 concentrations. The enrichment factor analysis indicates that the Rb, Sr, and Na originate from natural sources, while Fe, Al, Mn, K, Ca, Mg, and Zr have both natural and anthropogenic sources. The remaining elements are primarily of anthropogenic origin. Source apportionment through Principal Component Analysis (PCA) revealed the six key PM10 sources: mixed type (dust+biomass burning, 42%), vehicular (24%), industrial (15%), combustion (7%), agricultural activities (6%), and fossil fuel combustion (6%). Local sources from the northwest (NW) and west (W) directions were dominant, with smaller contributions from trans-boundary regions like Afghanistan and Pakistan. Health risk assessments highlighted non-carcinogenic risks from Mn for adults and children, with additional risks from Al and Cr for children, and carcinogenic risks from Cr for adults. The risk of Al, Cr and Mn in Varanasi are likely driven by combustion related activities, as Cr and Mn in PM10 are commonly associated with industrial and vehicular emission sources. © 2024 Elsevier Ltd