Browsing by Author "Sangeeta Gehlot"

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A cross sectional study on analysis of human milk as per prakriti psychosomatic constitution
(Enviro Research Publishers, 2020) Deeksha Singh; B.M. Singh; Sangeeta Gehlot; Vandana Verma
Background: Ayurveda scholars have given comprehensive descriptions about characteristics of pure and vitiated human milk, measures of its purification, effect of diet, lifestyle on quality of human milk and its effect on growth and development of infant. Recent researches have also shown that the variation in human milk composition is associated with the maternal diet, environment, and potentially with genetic factors. Studies have reported that individual mothers within species often demonstrate variation in milk composition and/or yield affecting infant growth and development. Prakriti refers to genetic account of an individual, so there may be variation in human milk composition because of metabolic peculiarity and dietary differences. Aim and Objectives: To analyze the composition of pure and vitiated Human milk as per Prakriti. Materials and Method: Total 200 healthy lactating Indian mothers, aged between 20 to 35 years were registered after getting informed written consent from OPD of Department of Kaumar bhritya, I.M.S, BHU, Varanasi, India during year 2015-2017. Analysis of milk for fat, SNF, density, protein, lactose, freezing point, conductivity and pH was done through Eco milk Analyzer. The vitiation of milk was assessed by water test mentioned in Ayurveda text viz. Charak Samhita, Sushruta Samhita, Ashtanghridyam, Kashyap Samhita etc. Assessment of Prakriti (Psychosomatic constitution) of mothers was done by validated Performa. Results: The mean values of different constituents viz. Fat(%), SNF(%),Density(g/cm3), Protein (%) and Freezing Point(°C) were more in vitiated milk as compared to pure human milk. The variation in composition of milk was also found as per Psychosomatic constitution, the mean values in milk varied significantly as per Prakriti (p=0.0287). On applying Post Hoc Test, the significant pairs were for Vata v/s Pitta (<0.05) and Vata v/s Kapha (<0.05) Prakriti. Conclusion: Present study suggests that the composition of human milk varies as per Prakriti and in vitiated state too. Thus by correction of diet and lifestyle as per Prakriti, the quality of breast milk may be improved and better growth of infants may be obtained by using medicines for purification of milk. © 2020 The Author(s). Published by Enviro Research Publishers.
A scientific Exploration on Concept of Chronomedicine and Chronotherapy in Ayurveda
(Informatics Publishing Limited, 2019) Sonam Agrawal; Vandana Verma; Sangeeta Gehlot
Human physiology and pathophysiology of diseases have been proved to show rhythmic variation in response to temporal factors. This behavior is intertwined in field of clinical physiology in form of chronomedicine and chronotherapy for the better outcomes of treatment. Ayurveda scholars have also described rhythmic variation in biological entities like Dosha, Agni, Bala, presentation of diseases in relation to diurnal, meal intake and seasonal factors. They have well documented different domain of drug i.e. collection of drug, preparation of medicine, intervention of therapeutic procedures and administration of medicine in accordance to variation in biological entities and time. This article is aimed to summarize all these documented observations of Ayurveda regarding chronomedicine and chronotherapy and discuss in view of contemporary sciences, so that it can be utilized by the researchers of this field to generate evidence based data and may be applied by the physician for the better prognosis and management of the disease. © 2019, Informatics Publishing Limited. All rights reserved.
Ayurveda insights on physiology of sweating and thermoregulation
(Informatics Publishing Limited, 2019) Vandana Verma; Sangeeta Gehlot; Sonam Agrawal
Physiology of sweating and thermoregulation was well conceived by Ancient Ayurveda scholars. The detailed description of Svedavaha Srotas (channels carrying sweat), Sveda (sweat) as Mala (waste), its mechanism of formation on exposure to heat, therapeutic application of heat for inducing sweating under the concept of Svedan Karma (sudation) for purification and balancing the Dosha for management of disorders reflects the deep understanding of Ayurveda scholars about the physiology of sweating and temperature regulation. Keeping these facts in mind a detailed review has been done as an attempt to understand the physiology of sweating and temperature regulation mechanism described in Ayurveda in view of contemporary sciences and recent researches. © 2019, Informatics Publishing Limited. All rights reserved.
Basis of disease manifestation: A molecular and Ayurvedic approach with an integrated concept of Ayurgenomics
(Informatics Publishing Limited, 2019) Shriti Singh; Sangeeta Gehlot; N.K. Agrawal
Ayurveda and contemporary science comprehends human body as model to understand disease state from very different perspective hence their methodology to describe disease manifestation also seems very different as they observe same problem from different viewpoints. For more precision in healthcare system it is essential that best of both systems need to be integrated, In Ayurvedic texts, the description of concept of basic constitution/Prakriti in health and disease states is well described. The scripts are not clearly understandable and hence its importance has not been properly understood by contemporary biological researchers and thus not utilized. According to Ayurveda individual’s basic constitution (Prakriti) influences and directs one’s disease status, its treatment & lifestyle regimen. In genomics, individual’s basic constitution is decided by its genetic makeup. The current trend in Ayurveda-related biomolecular studies is establishment of high correlation between Prakriti and Genomics. This approach of Ayurgenomics would facilitate the development of alternative methods for cost effective screening of predisposed individuals in the population. This would result in development of an integrated approach to systems biology for disease and health state. For the establishment and success of this concept the prerequisite is integration of Ayurveda into mainstream contemporary biology to achieve global acceptability for the concepts and science of Ayurveda, and for this Ayurvedic concept based phenotypic (Prakriti) assessment needs to be made so that difference among individuals from large population based on their physical, physiological and psychological status can be observed and they can be categorized by their specific predominant Prakriti i.e. Vata, Pitta, Kapha. Information about individual predominant Prakriti can be further analyzed on certain genomic parameters related to gene expression, genetic, epigenetic and biochemical factors, which can be further utilized for Integration of Ayurveda with Genomics for systems biology approach in predictive and personalized medicine. © 2019, Informatics Publishing Limited. All rights reserved.
Clinical Prediction of Type 2 Diabetes Mellitus (T2DM) via Anthropometric and Biochemical Variations in Prakriti
(Multidisciplinary Digital Publishing Institute (MDPI), 2022) Shriti Singh; Neeraj Kumar Agrawal; Girish Singh; Sangeeta Gehlot; Santosh Kumar Singh; Rajesh Singh
Type 2 Diabetes Mellitus (T2DM) is a complicated multifactorial illness involving hereditary and external environmental variables. The symptoms typically appear gradually over a number of years without realizing it. This viewpoint is further supported by the Ayurvedic constitution concept (Prakriti). Prakriti explains the biological variability that is observed in different individuals. This study was conducted a retrospective investigation to examine if there was a link between type 2 diabetes and an individual’s constitution based on anthropometric and biochemical characteristics. Physical and mental characteristics and anthropometric and biochemical markers were used to determine reported cases’ prevailing Dosha Prakriti (constitution). Based on biochemical and anthropometric data, significant differences in Prakriti were found between the case (T2DM patients) and control (person without diabetes) groups. The incidence of numerous secondary problems linked with T2DM patients was also evaluated according to their Prakriti types, which revealed a positive relationship. The three primary contributing parameters, such as waist-hip ratio, postprandial blood sugar, and serum creatinine, were correctly classified all person with or without diabetes subjects to 90.6% of the time, whereas the constitution-wise study classified person with diabetes and without diabetes individuals of Pitta and Kapha Prakriti to 94.3% and 90%, respectively. A discriminant function was created to predict a person with diabetes and without diabetes based on these three contributing factors. The primary contributing biochemical parameters discovered by Prakriti in the current study could be used as a biochemical disease diagnostic for predicting type 2 diabetes susceptibility. © 2022 by the authors.
Congruence with health by divergence in uses of water: An ayurvedic notion
(Enviro Research Publishers, 2019) Anam Aftab; Vandana Verma; Sangeeta Gehlot
In the vocation of nutrition science, tremendous research has been executed over the analysis of food, its chemistry, conservation, preparation, consumption, production, deficiencies and so on. Even in present time professionals have pinned their eye over the manner of intake of food too, but the water being very essential element for survival has not been yet attracted the attention of the heavenly body. Ayurveda, one of the most ancient traditional systems of medicine contemplated water as an endorser of life which plays a pivot role in attaining vigor or occurrence of maladies. The scriptures divulged the facts that proper nourishment and metabolism of body also rely on the quality, quantity and even on the right manner of intake of water along with other major nutrients, and regarding this, a very comprehensive narrative is found in all the obtainable treatises of ancient medical science. This inspires the researcher to highlight such codes which can be directed as an additive protocol for the human being having pursuance of health. Moreover, an extensive search has also been performed to find out the parallel scientific evidences regarding the dogmas which can be established over the scientific background, so to make it more acceptable and admissible in the community and to also provide a pointer on which further research could be carried out. © 2019 The Author(s). Published by Enviro Research Publishers.
Development, validation and verification of a self-assessment tool to estimate Sadhaka Pitta (Mental strength)
(J. K. Welfare and Pharmascope Foundation, 2020) Vijay Laxmi Gautam; T.B. Singh; Sangeeta Gehlot; Hari Hridaya Awasthi
The holistic approach of Ayurveda, treating the patient as a whole, meaning intervention targeted toward complete physical, psychological, and spiritual well-being. Sadhaka Pitta is the factor responsible for mental health and mental strength (weak and strong Sadhaka Pitta functions) assattva. It is the sub-dosha of pitta among the five types. The primary objective of the study was to develop and validate a self-assessment tool to estimate Sadhaka Pitta. The developed tool was evaluated for its reliability and validity by administering to 50 healthy volunteers of either gender belonging to 21 to 50 year age groups. Besides confirming the statistical validity and reliability, the applied utility of the newly developed tool was evaluated by mental health based on Sadhaka Pitta functions parameters of all the volunteers. The results show that the mental functions controlled by brain, vary significantly according to functions of Sadhaka Pitta. The tool therefore can be used to screen normal population to look for possible susceptibility to certain behaviours. © 2020 International Journal of Research in Pharmaceutical Sciences. All rights reserved.
Development, Validation, and Verification of a Self-Assessment Tool to Estimate Agnibala (Digestive Strength)
(SAGE Publications Ltd, 2017) Aparna Singh; Girish Singh; Kishor Patwardhan; Sangeeta Gehlot
According to Ayurveda, the traditional system of healthcare of Indian origin, Agni is the factor responsible for digestion and metabolism. Four functional states (Agnibala) of Agni have been recognized: regular, irregular, intense, and weak. The objective of the present study was to develop and validate a self-assessment tool to estimate Agnibala. The developed tool was evaluated for its reliability and validity by administering it to 300 healthy volunteers of either gender belonging to 18 to 40-year age group. Besides confirming the statistical validity and reliability, the practical utility of the newly developed tool was also evaluated by recording serum lipid parameters of all the volunteers. The results show that the lipid parameters vary significantly according to the status of Agni. The tool, therefore, may be used to screen normal population to look for possible susceptibility to certain health conditions. © 2016, © The Author(s) 2016.
Effect of circuit training and yogasanas on cardiovascular endurance, inspiratory capacity and forced vital capacity among sports person with special reference to prakriti
(Informatics Publishing Limited, 2019) Sandeep Singh; Sangeeta Gehlot
Background: Circuit training and Yogasana are good for the development of physical and physiological fitness of an individual. These training methods are useful to develop the individual’s fitness component like strength, speed, cardiovascular endurance, flexibility and agility as well as physiological components like Forced Vital Capacity (FVC), Inspiratory Capacity (IC) and Expiratory Capacity (EC). Thus, this study was planned to find out the variation of cardiovascular endurance, inspiratory capacity and forced vital capacity among sport persons through circuit training and Yogasana practice in different Prakriti individuals. Materials and Methods: 60 young and healthy male of age group 18-28 years, inter university level sport players were selected and divided into three groups, two experimental group (Yogasana and circuit training group) and one control group. Prakriti of each player was determined by the standard proforma. Harvard step test and PFT was done before and after completion of intervention. Result: After intervention significant changes were found in cardiovascular endurance, forced vital capacity and inspiratory capacity. Pair wise comparison of groups resulted in significant difference between circuit training group v/s control group and Yogasana group v/s control group in FVC and IC, circuit training group v/s Yogasana groups in IC. On Prakriti wise analysis significant changes were observed in all the three parameters of all Prakriti players of circuit training group while, Yogasana group showed significant difference in different parameters. No change was found in control group. Conclusion: Circuit training and Yogasana practices produced almost similar response on all studied parameters. © 2019, Informatics Publishing Limited, All rights reserved.
Explication on tissue nutrition in prenatal and postnatal life: An Ayurveda perspective
(Elsevier B.V., 2021) Sonam Agrawal; Vandana Verma; Sangeeta Gehlot
Tissue nutrition is the continuous process which is established just after the conception and persists throughout the life. Ayurveda scholars have mentioned that the manner of tissue nutrition is not same in all phases of life. In prenatal life embryo gets nutrition by Upasneha (filtration) and Upasweda (percolation/secretion) and fetus by Garbhanabhinadi (umbilical cord) which is attached with the heart of mother via Rasavahanadi (blood vessels). Thus in intrauterine life the nutrition of embryo is histotrophic, whereas just after the formation of placenta nutrition becomes haemotrophic. In post-natal life nutrition is enteral means nutrients are taken in the form of food via mouth called Aahar. Ayurveda scholars have postulated theories to understand the mechanism of tissue nutrition are Ksheera Dadhi Nyaya (transformation of nutrients), Khale Kapota Nyaya (selective uptake of nutrients), KedariKulya Nyaya (transportation of nutrients via channels), Ek Kala Dhatu Poshan Nyaya (simultaneous supply of nutrients to whole body). The theories of tissue nutrition discussed in Ayurveda suggest that although tissues are nourished and replenished continuously at different rate as per the functional state of Agni by circulating nutrients obtained from Ahara, but tissues are also dependent on each other for their proper nourishment and metabolism. This concept has great implication in management of malnourishment and various other disorders. This manuscript is an attempt to explore the Ayurveda's view on tissue nutrition along with physiological and clinical significance of theories of tissue nutrition in a scientific manner. © 2020 The Authors
Exploration of Ayurveda blueprint on clinical physiology of Meda (adipose tissue) and Majja dhatu (bone marrow) in context to obesity
(J. K. Welfare and Pharmascope Foundation, 2020) Vandana Verma; Sonam Agrawal; Sangeeta Gehlot
The state of health depends on the functional state of Dosha, Dhatu, Mala, Srotas, and Agni. The concept of functional and nutritional interdependence of Dhatu as well as a physiological and pathological aspect of all the seven Dhatu has been described by Ayurveda scholars. The metabolic effect of Meda and Majja Dhatu on other tissues like a muscle (Mamsa Dhatu), bone (Asthi Dhatu), and reproductive tissue (Shukra Dhatu) show their functional interdependence. The Ayurveda compendia, as well as recent research data, shows that obesity is the disorder of nutrition, which depends on lifestyle and diet. The obesity has been discussed in relation to Medovaha Srotodushti and Meda Dhatu Vriddhi. Although the physiology of Vasa, Meda, and Majja tissue has not been elaborated much, their clinical physiology has been described. This article aims to comprehend the pathophysiology of obesity as well as manifestations on the disturbed functional state of Meda and Majja Dhatu, as depicted by Ayurveda scholars in light of contemporary science. This article will be helpful in developing a vision regarding the clinical physiology of Meda and Majja, which will be further helpful in the exploration of pathophysiology and the management of obesity and associated disorders manifested by them. On exhaustive study, it was observed that the clinical physiology of Meda and Majja Dhatu shares quite a resemblance with the outcomes of contemporary researches on adipocytes, but still, some of these are still under the research. © 2020 International Journal of Research in Pharmaceutical Sciences. All rights reserved.
Historical perspectives of nutrition science: Insights from Ayurveda
(Informatics Publishing Limited, 2019) Veena; Vandana Verma; Sangeeta Gehlot
Nutrition is the science that interprets the interaction of food in relation to maintenance, growth, health and disease of an organism. The history of nutrition science and dietetics can be traced back as far as history of civilization across the world. The food habits, cooking and food processing have been evolved with cultural development of human beings. The ancient physicians from Greek, Hippocrates, Galen, Plato, Chinese civilization and Indian physician of Ayurveda like Charak and Sushruta have duly recognized the importance of diet and dietetics along with physical activity in health and management of various disorders. Although the advancement in nutrition science has added the discovery of various micronutrients and fortified food substances, still a large number of populations worldwide is suffering from disorders of malnutrition, food-borne diseases, neurotoxins and other non-communicable diseases due to wrong cooking, storage, packaging practices and intake of food in wrong combination. Ayurveda has advocated that to get the optimum benefits from the consumed food (Aahara), people should give due consideration to their psychosomatic constitution (Prakriti), state of digestive power (Agni), age, dietary rules, nature and combination of food etc. It is very surprising fact that scientific development of nutrition science was started in between 18th and 19th century, but the researchers and academicians working in the field of nutrition and medicinal health science have not incorporated the valuable, time tested knowledge of Ayurveda, which could be applied for development of nutrition science, and will be helpful in treatment of diseases and maintenance of health too. © 2019, Informatics Publishing Limited. All rights reserved.
Molecular study of the KCNJ11 gene and its correlation with Prakriti to preventing and managing type 2 diabetes
(National Taiwan University, 2024) Shriti Singh; Sangeeta Gehlot; Neeraj Kumar Agrawal; Girish Singh; Devshree Singh; Prabhjot Kaur; Santosh Kumar Singh; Rajesh Singh
In Ayurveda, every individual is believed to possess a unique entity known as Prakriti, which distinguishes them from others physically, physiologically, and psychologically. This entity also determines an individual's response to a particular stimulus, and it is believed that such responses are not solely determined by genetics. The present research aims to validate the Ayurvedic concept of Prakriti from a modern molecular perspective to strengthen the personalized and precise treatment approach. A study was conducted to investigate the role of the KCNJ11gene in the susceptibility of individuals to type 2 diabetes mellitus (T2DM) with their metabolic status. The research involved allele mining on three major Prakriti groups - Vata, Pitta, and Kapha - in 112 patients with T2DM and 112 healthy individuals. The KCNJ11 gene, responsible for insulin secretion membrane pore formation, was analyzed to determine the susceptibility of different Prakriti types to T2DM. The MutPred tool predicted the molecular cause of disease-related amino acid substitution. According to the study, only Pitta and Kapha Prakriti were diagnosed with diabetes, while all three Prakriti types were present in the control group of healthy individuals. A protein model was prepared, and the changes resulting from mutations were observed for each group in their protein sequence, both as synonymous and non-synonymous mutations. Ultimately, these changes contributed to the manifestation of T2DM. Based on the findings, it appears that Prakriti groups may experience changes in protein function due to nonsynonymous mutations and differences in amino acids at the protein level. © 2024 Center for Food and Biomolecules, National Taiwan University
Overlooked contributions of Ayurveda literature to the history of physiology of digestion and metabolism
(Springer Science and Business Media Deutschland GmbH, 2023) Aparna Singh; Sonam Agrawal; Kishor Patwardhan; Sangeeta Gehlot
Ayurveda is a traditional system of healthcare that is native to India and has a rich documented literature of its own. Most of the historians agree that the documentation of core Ayurveda literature took place approximately in between 400 BCE and 200 CE, while acknowledging that the roots of its theoretical framework can be traced back to a much earlier period. For multiple reasons many significant contributions of Ayurveda literature to various streams of biological and medical sciences have remained under-recognized while recounting the historical milestones of development. This is true in the context of the physiology of digestion and metabolism too. In this communication we try to reconstruct a picture of the processes of digestion and metabolism as had been understood by ancient Ayurveda scholars. Though this understanding was primitive and insufficient in many ways, we argue that this deserves to be documented and acknowledged. To help with grasping the importance of these contributions, we juxtapose them with the corresponding insights pertaining to this subject reported by prominent western scientists. The major contributions of Ayurveda that have been recounted in this paper are those related to the description of three distinct phases of digestion (Avasthapaka), multiple sets of transformative entities acting at different levels of metabolism (Agni), and the roles ascribed to various internal and external factors in executing these physiological functions. © 2023, Springer Nature Switzerland AG.
Response of Centella asiatica in the management of age related problems among elderly with special reference to cognitive problems as per Prakriti
(International Journal of Research in Ayurveda and Pharmacy, 2013) Rakesh Roushan; Sushma Tiwari; Sangeeta Gehlot; I.S. Gambhir
Centella asiatica causes an overall decrease in the yield of central monoamines, implicating the participation of nor epinephrine, dopamine and 5-HT in learning and memory process towards long term retention of information. More recently, a new study showed that components in Centella asiatica have potential for treating Alzheimer's disease and cognitive impairment. The study was designed to assess the effect of Centella asiatica on age related common health problems as per constitution of individuals. Patients aged 60 years and above were enrolled from geriatric O.P.D. Mini Mental State Examination (MMSE) is the most important diagnostic tool for our study along with the history of patients. Present study has showed that significant decrease in MMSE, blood pressure and sleeping disorders was observed in Vata and Pitta Prakriti individuals. In this study drug Centella asiatica was found to be highly effective in Mild cognitive impairment by improving the MMSE, Hypertension and sleeping pattern in elderly population.
Response of Paschimottanasana and Kapalabhati on anthropometric parameters in obese individuals as per Prakriti
(International Journal of Research in Ayurveda and Pharmacy, 2014) Ravi Shukla; Sangeeta Gehlot
Modernization, affluence, science and technological development have lead to still more sedentary life styles. By exposing oneself to all these factors human beings have unknowingly invited a number of diseases. Among which obesity is one of the most hazardous factor. Some Yoga postures like Paschimottanasana and Kapalabhati help to reduce weight with significant health benefits. But their response in obese individuals as per Prakriti was different; it may be due to change of Doshic composition in different individuals, i.e. main dominating factor in formation of Prakriti. Total 60 grade-1 obese subjects diagnosed as per WHO criteria were registered in Department of Kriya Sharir BHU Varanasi, India. These subjects were divided into two groups by random sampling method in group I and II. Group-I individuals were advised diet restriction plan whereas subjects of group II were suggested with Paschimottanasana and Kapalabhati as well as diet restriction plan. All the individuals were evaluated for anthropometric parameters like weight, BMI, WC, HC, WHR, BF % and VF %. For intra group comparison and inter group comparison paired sample t-test and independent sample t-test was applied. Statistical analysis showed highly significant response in terms of reduction in values for all the anthropometric parameters as per Prakriti after performing Paschimottanasana and Kapalabhati along with diet restriction in group II. Our study concludes that regular practice of Paschimottanasana and Kapalabhati along with diet restriction is more helpful in reducing obesity and this reduction was more in Kapha Vata Prakriti individuals.
The Ayurveda education in India: How well are the graduates exposed to basic clinical skills?
(2011) Kishor Patwardhan; Sangeeta Gehlot; Girish Singh; H.C.S. Rathore
"Ayurveda" is an ancient system of healthcare that is native to India. At present, in India, there are more than 240 colleges that offer a graduate-level degree (Bachelor of Ayurvedic Medicine and Surgery-BAMS) in Ayurveda. Even though the Central Council of Indian Medicine, the governing body that monitors the matters related to Ayurveda education, has imposed various educational norms and regulations, the standard of education has been a cause of concern in recent years. The mushrooming of substandard Ayurvedic colleges is the most important factor that is being held responsible for this kind of erosion in the standards. The present study is a mailed survey, which was carried out to evaluate the 33312Extent of exposure to basic clinical skills during BAMS course33313 as perceived by the sample groups of students and teachers drawn from 32 Ayurvedic educational institutions spread all over India. A methodically validated questionnaire was used as the tool in the study, to which 1022 participants responded. The study indicates that there are some serious flaws in the existing system of the graduate-level Ayurveda education. Since the Ayurvedic graduates play an important role in the primary healthcare delivery system of the country, governing bodies are required to take necessary steps to ensure the adequate exposure of the students to basic clinical skills. Along with the strict implementation of all the regulatory norms during the process of recognition of the colleges, introducing some changes in the policy model may also be required to tackle the situation. Copyright © 2011 Kishor Patwardhan et al.
Validating the properties of ranunculus sceleratus linn. By performing spectroscopic techniques and modern chromatography
(J. K. Welfare and Pharmascope Foundation, 2020) Madhulika; K.N. Dwivedi; Sangeeta Gehlot
Ranunculus sceleratus Linn. is one of the well-known medicinal plants, being used from the ancient time in India and commonly called as “Jal dhaniya”. It belongs to Ranunculaceae family derived from two Latin Words “Rana” means frog and “unculus” means little and referred together as “little frog” and also species sceleratus for cursed. It is an aquatic perennial herb. It consists of a herbaceous hollow stem, firm tap root, branched rhizome and leaves having a smooth upper side. The green plant is toxic for livestock and uncomfortable to human skin. This plant can grow up to 0.60 m tall, and also used as a food, medicine and possess other uses. Ranunculus sceleratus Linn. is commonly spread in the temperate and cold region in Global distribution (Indonesia, Malaysia, Nepal, Sri Lanka and India). According to Bentham and Hooker classification “Genera Plantarum”, this plant belongs to the division Polypetale of Dicotyledones which processes more than 600 species. The Phytochemical screening was performed according to API norms, in addition to this UV VIS, FTIR, TLC and HPLC test were also carried out for further validation. The spectroscopy and chromatography examination revealed the presence of flavonoids, phenols and various other Phytoconstituents in Ranunculus sceleratus Linn. The spectroscopy and chromatography validation can help us it for medicinal and commercial purposes. © 2020 Global Research Online. All rights reserved.
Variations of human milk compositions as per prakriti (Psychosomatic constitution): A pilot study
(Informatics Publishing Limited, 2019) Deeksha Singh; Sangeeta Gehlot; B.M. Singh; D.C. Rai
Introduction: Mother’s milk is considered to be the supreme food for neonates, infants and toddler. It is also regarded as the finest gift form a mother to her baby. The individual characteristic of a person enumerating external and internal body features is known as Prakriti. It is the sense of personality or constitution or temperament of an individual. The aim of the present study was to assess “variations of human milk composition as per Prakriti”. Materials and Methods: Total 64 lactating mothers of 20-35 years age group, not suffering from any acute or chronic illness and who were on similar diet regardless of their mode of delivery were registered and included in the study while lactating mothers not falling in this age group or who were taking any specific drug for the illness or suffering from any disease including- moderate (9.97-7 g/dl) to severe (6.94-4 g/dl) anemia were excluded from the study. Result: On applying One Way ANOVA, the mean values of fat percentage in milk varied significantly as per Prakriti (p = 0.0287). On applying Post Hoc Test the significant pairs were for Vata vs. Pitta (<0.05) and Vata vs Kapha (<0.05) Prakriti. In all other parameters of milk, no significant variation was found. Conclusion: We can conclude that the composition of mother’s milk varies as per Prakriti. © 2019, Informatics Publishing Limited, All rights reserved.
Weighted mean: A possible method to express overall Dhatu Sarata
(Medknow Publications, 2015) Chandar Prakash Gunawat; Girish Singh; Kishor Patwardhan; Sangeeta Gehlot
Several questions are being raised regarding the accuracy of the methods of diagnosis and reporting of various clinical parameters according to Ayurveda in recent times. Uniformity in reporting, issues related to inter-rater variability, uniformity in applying statistical tests, reliability, consistency, and validation of various tools, - are some of the major concerns that are being voiced. Dhatu Sarata is one such domain where no substantial work has been carried out to address these issues. The Sanskrit term Dhatu roughly translates as a tissue.. Sarata stands for the status of Dhatu in a given individual, i.e., it describes whether the status is excellent, moderate, or poor. In the available research literature, there are several gaps while dealing with and reporting the clinical assessment of Dhatu. Most of the workers group an individual into any one of the categories of Dhatu Sarata, and this approach neglects the contribution of other Dhatus to the overall Sarata in that individual. In this communication, we propose the usefulness of weighted mean in expressing the overall Sarata in an individual. This gives the researcher a freedom of not classifying an individual into any one group of Sarata, while also simultaneously allowing him/her to retain the focus on the status of an individual Dhatu. © 2015 Journal of Ayurveda & Integrative Medicine.