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Browsing by Author "Sergey Shastun"

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    PublicationReview
    Can functional food security decrease the epidemic of obesity and metabolic syndrome? A viewpoint
    (Nova Science Publishers, Inc., 2016) Sergey Shastun; Anil K. Chauhan; Ram B. Singh; Meenakshi Singh; Ravi P. Singh; Arunporn Itharat; Sergey Chibisov; Fabien De Meester; Douglas W. Wilson; Ghazi Halabi
    The world is still ignorant about the role of functional food security characterized by diversity and adequacy of nutrients that may have been beneficial and abundant in the Paleolithic diet 40,000 years ago because of food diversity. Therefore, the increased prevalence of metabolic syndrome and the resultant type 2 diabetes, hypertension and heart disease throughout the world, are closely linked to food security via westernized dietary patterns, physical inactivity, and rapid increase in the rate of obesity. There is substantial evidence that increased intake of functional foods can bring about a significant decline in the epidemic of obesity and metabolic syndrome, resulting in health promotion. We therefore propose that functional food security can maintain the normal physiology and metabolism of our bodies, resulting in prevention of diseases and improvement of world health. © 2016 Nova Science Publishers, Inc.
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    Fenugreeg seeds decrease blood cholesterol and blood glucose as adjunct to diet therapy in patients with hypercholesterolemia
    (Nova Science Publishers, Inc., 2016) Jan Fedacko; R.B. Singh; M.A. Niaz; Saraswati Ghosh; Petra Fedackova; A.D. Tripathi; Arunporn Etharat; Ekasit Onsaard; V.K. Singh; Sergey Shastun
    Background. Hypercholesterolemia, diabetes and obesity are risk factors of cardiovascular diseases (CVDs), and most agencies advise a prudent low fat diet for treatment. Plant health products are rich sources of fiber and flavonoids which are known to inhibit athero-thrombosis due to hypolipidemic, hypoglycemic and insulin sensitivity activating effects. In the present trial, we examine the effects of fenugreek seeds on risk of CVDs. Design and setting. Randomized, double blind, placebocontrolled trial in a hospital. Subjects and Methods. All subjects (n = 61) with hyperlipidemia (<7.76 nmol/l) were assigned to American Heart Association step 1 diet for a period of 12 weeks and then randomized to two different intervention agents in identical sachets for another 12 weeks. The test agents were fenugreek seed powder (60.0g/day) and cellulose placebo (3.g/day). Results: Of 61 subjects with serum cholesterol between 5.17 and 7.76 nmol/1, 59 successfully completed 12 weeks of AHA step I diet and then augmented the diet with one of the fiber or fenugreek supplement for 12 additional weeks. Incremental differences from placebo for low-density lipoprotein (LDL) cholesterol were: -15.1% (P < 0.001) for fenugreek; for total cholesterol -13.4% (P < 0.001) for fenugreek. The incremental differences in triglycerides (significant) for fenugreek were -9.2% (P < 0.001) with a 4.4% (P < 0.05) increase in HDL cholesterol. LDL/HDL cholesterol ratio showed a statistically significant decline from the reference concentrations in the fenugreek group, but no such changes in the control group; the incremental difference was 11.4% (P < 0.001). The incremental differences in fasting and postprandial blood glucose, which showed statistically significant declines in the fenugreek group compared to the control group, were 9.8% (P < 0.05) and 19.4% (P < 0.001), respectively. Compliances to treatment varied between 92% and 99% and only mild gastrointestinal side effects were observed. Conclusions: Treatment with fenugreek seeds revealed statistically significant hypoglycemic and hypocholesterolemic effects on AHA step 1 diet effects. © 2016 Nova Science Publishers, Inc.
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    Holistic approaches for health education and health promotion
    (Nova Science Publishers, Inc., 2017) Arunporn Itharat; Toru Takahashi; R.G. Singh; R.B. Singh; Krisana Krisentu; Raima Lobenberg; Hiroshi Noguchi; Ibrahim Jantan; Telessy G. Istvan; Douglas W. Wilson; Sergey Shastun; H.S. Buttar; Galal Elkilany; Krasimira Hristova; Germaine Cornélissen; Laila Hussain; Ahmad Sulaeman; Mukta Singh; R.K. Srivastav
    Modern approaches: moderate physical activity, a functional food-rich diet, reduction of body weight, control of blood pressure and blood lipids by drug therapy, cessation of tobacco and alcohol use, for health promotion and prevention of non-communicable diseases (NCDs) have only partial benefit on future risk of these diseases, despite the high health budget in high-income countries. Holistic approaches to health education and holistic health may provide better health and may be more successful in the prevention of cardiovascular diseases (CVDs) and other chronic diseases. There is evidence that psychosocial stress, late night sleep and late night eating, as well as sleep deprivation, deficiency of nutrients such as omega-3 fatty acids, vitamins and flavonoids can have adverse effects on brain-body mechanisms, resulting in obesity and insulin resistance, leading to CVDs and other chronic diseases. However, active prayer, kirtan krea, verbalization, yogasan and meditation, along with Mediterranean style-functional food-rich diet as well as nutraceuticals and herbs may be protective against NCDs. © 2017 Nova Science Publishers, Inc.
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