Browsing by Author "Shiv Prakash"

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Effect of motivational enhancement therapy and behavioral couple therapy in subjects of alcohol dependence syndrome: A comparative study
(Wolters Kluwer Medknow Publications, 2022) Saurav Kumar; Mona Srivastava; Manushi Srivastava; Jai Singh Yadav; Shiv Prakash
Background: Alcohol dependence is a wide and extending social and physical problem in the world. It affects a person at the individual, family, and society levels. The aim is to study and compare the influence of motivational enhancement therapy (MET) and behavioral couple therapy on the level of motivation in a person with alcohol dependence. Methodology: Pre- and post-test with control group design was used. A total number of 60 subjects were selected using a purposive sampling method. The sample comprised twenty subjects in the behavioral couple therapy treatment as usual (Behavioral couple therapy BCT + TAU) group, twenty subjects in the control (TAU) group, and twenty subjects in the (MET + TAU) group, respectively. The subjects recruited were in the age range of 21-60 years, educated up to primary level and above, with no comorbid psychiatric, neurological disorder, physical problem, multiple substance use coming to outpatient department and inpatient department Department of Psychiatry IMS, BHU, Varanasi, and wife having age above 18 years, married for at least 1 year, educated up to primary level and above. Tools: sociodemographic datasheets, alcohol use disorder identification test, general health questionnaire-12, and stages of change readiness and treatment eagerness scale were utilized. Results: Psychotherapeutic intervention such as MET and behavioral couple therapy plays an effective role in raising motivation to change in alcohol-dependent person to quit alcohol, which is indicated by the significant rise in motivation for the change of alcohol-dependent person's recognition (F = 4.42, P < 0.05) and taking steps (F==3.78, P < 0.05). Conclusion: The present study suggests that combining pharmacological treatment with appropriate psychosocial therapies give fruitful result in the form of a desire to quit alcohol dependence. © 2022 The authors.
Non-enzymatic Determination of Uric Acid by Ion Exchange Voltammetry at a Permselective Electrochemical Sensing Platform
(Taylor and Francis Ltd., 2015) Pankaj Kumar Rastogi; Rupali Gupta; Shiv Prakash; Vellaichamy Ganesan
Here we demonstrate a new strategy for electrochemical determination of uric acid (UA) using a cationic polymer as an electrochemical sensing platform (ESP). The cationic polymer is based on branched polyethylenimine (BPEI) cross-linked with ethylene glycol diglycidyl ether (EGDE). Ion exchange property of this cross linked cationic polymer (BPEI-EGDE) with negatively charged electroactive species is studied by cyclic voltammetry. Furthermore, this cationic cross-linked BPEI-EGDE polymer is coated on a glassy carbon electrode (GC) to construct the ESP for the quantitative analysis of biologically important molecule, UA at pH 7.0. It shows efficient oxidation of UA with respect to bare GC due to favorable electrostatic interaction of anionic UA with the positively charged BPEI-EGDE film. Finally it is demonstrated that the BPEI- EGDE films can be used as efficient ESP for non-enzymatic UA determination in the concentration range of 5 to 1500 µM with a sensitivity of 153 µA μM-1cm-2. © 2015, Har Krishan Bhalla & Sons.