Browsing by Author "Suman Sarkar"

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Artificial blood
(Medknow Publications and Media Pvt. Ltd, 2008) Suman Sarkar
Artificial blood is a product made to act as a substitute for red blood cells. While true blood serves many different functions, artificial blood is designed for the sole purpose of transporting oxygen and carbon dioxide throughout the body. Depending on the type of artificial blood, it can be produced in different ways using synthetic production, chemical isolation, or recombinant biochemical technology. Development of the first blood substitutes dates back to the early 1600s, and the search for the ideal blood substitute continues. Various manufacturers have products in clinical trials; however, no truly safe and effective artificial blood product is currently marketed. It is anticipated that when an artificial blood product is available, it will have annual sales of over $7.6 billion in the United States alone.
Cerebral malaria caused by Plasmodium vivax in adult subjects
(Medknow Publications and Media Pvt. Ltd, 2008) Suman Sarkar; Prithwis Bhattacharya
Cerebral malaria is a diffuse encephalopathy associated with seizures and status epilepticus which can occur in up to one-third of patients with severe malaria, particularly that caused by Plasmodium falciparum. In this article, we report three cases of Plasmodium vivax malaria (all adult male patients) complicated by seizures and symptoms of diffuse meningoencephalitis. Two patients had predominantly meningeal signs, while in the third patient the features were purely of encephalitis All cases were treated with artesunate. Usually, cerebral malaria is caused by P. falciparum, and rarely, cerebral malaria is a presenting complication or occurs during the course of P. vivax infection.
Cerebrovascular manifestations and alteration of coagulation profile in scorpion sting: A case series
(Medknow Publications and Media Pvt. Ltd, 2008) Suman Sarkar; Prithwis Bhattacharya; Anil Paswan
Cerebrovascular manifestations are uncommon presentations of scorpion sting in the Indian subcontinent. A prospective study was carried out on 42 patients with scorpion sting in the intensive care unit (ICU) of the Institute of Medical Sciences, Banaras Hindu University, Varanasi-05, INDIA, during the period of May 2005 to October 2007. In all the patients detailed history, physical examination with a specific neurological examination and routine biochemical testing and fundus examination were done. Computerized tomography and magnetic resonance imaging were done in cases with neurological deficit. All these patients also underwent a complete hematological, rheumatologic and cardiovascular work-up for stroke. Cerebrovascular involvement was noted in three patients (7.15%). Hemorrhagic stroke was noted in two patients (4.77%) and thrombotic stroke was noted in one patient (2.39%). The mean time of presentation of neurological symptoms was 3 days. Contrary to world literature, there have been no reports of cranial nerve palsies or neuromuscular involvement in our series.
Changes of splanchnic perfusion after applying positive end expiratory pressure in patients with acute respiratory distress syndrome
(Medknow Publications and Media Pvt. Ltd, 2009) Suman Sarkar; Prithwis Bhattacharya; Indrajit Kumar; Kruti Mandal
Background: Positive end-expiratory pressure (PEEP) improves oxygenation and can prevent ventilator- induced lung injury in patients with acute respiratory distress syndrome (ARDS). Nevertheless, PEEP can also induce detrimental effects by its influence on the cardiovascular system. The purpose of this study was to assess the effects of PEEP on gastric mucosal perfusion while applying a protective ventilatory strategy in patients with ARDS. Materials and Methods: Thirty-two patients were included in the study. A pressure-volume curve was traced and ideal PEEP, defined as lower inflection point + 2cmH2 O, was determined. Gastric tonometry was measured continuously (Tonocap). After baseline measurements, 10, 15 and 20cmH 2 O PEEP and ideal PEEP were applied for 30 min each. By the end of each period, hemodynamics, CO2 gap (gastric minus arterial partial pressures), and ventilatory measurements were taken. Results: PEEP had no effect on CO2 gap (median [range], baseline: 18 [2-30] mmHg; PEEP 10: 18 [0-40] mmHg; PEEP 15: 17 [0-39] mmHg; PEEP 20: 16 [4-39] mmHg; ideal PEEP: 19 [9-39] mmHg; P = 0.19). Cardiac index also remained unchanged (baseline: 4.7 [2.6-6.2] l min1 m2 ; PEEP 10: 4.4 [2.5-7] l min 1 m2 ; PEEP 15: 4.4 [2.2-6.8] l min1 m 2 ; PEEP 20: 4.8 [2.4-6.3] l min1 m2 ; ideal PEEP: 4.9 [2.4-6.3] l min1 m2 ; P = 0.09). Conclusion: PEEP of 10-20 cmH2 O does not affect splanchnic perfusion and is hemodynamically well tolerated in most patients with ARDS, including those receiving inotropic supports.
Metabolic alkalosis: A less appreciated side effect of Imipenem-cilastatin use
(Wolters Kluwer Medknow Publications, 2013) Pragyan Swagatika Panda; Surya Kumar Dube; Suman Sarkar; Dinesh Kumar Singh
[No abstract available]
Metabolic alkalosis: A less appreciated side-effect of imipenem cilastatin use-author's reply
(Wolters Kluwer Medknow Publications, 2014) P.S. Panda; Surya Kumar Dube; Suman Sarkar; D.K. Singh
[No abstract available]
Successful management of massive intraoperative pulmonary fat embolism with percutaneous cardiopulmonary support
(Medknow Publications and Media Pvt. Ltd, 2008) Suman Sarkar; Krutisundar Mandal; Prithwis Bhattacharya
We report a patient who sustained catastrophic pulmonary fat embolism, during open reduction, internal fixation (ORIF) of fracture femur' In our opinion, the use of percutaneous cardiopulmonary support with (PCPS), saved the patient from certain death.
Use of the pro-seal laryngeal mask airway facilitates percutaneous dilatational tracheostomy in an intensive care unit
(Wolters Kluwer Medknow Publications, 2010) Suman Sarkar; P. Shashi; Anil Kumar Paswan; R.P. Anupam; S. Suman; Surya Kumar Dube
Purpose: To study the feasibility of using the pro-seal laryngeal mask airway (LMA) for airway maintenance during bronchoscopic-guided percutaneous tracheostomy. Materials and Methods: Observational study of 60 patients in a 16-bed intensive care unit. The patient's tracheal tube was exchanged for a pro-seal LMA before undertaking percutaneous tracheostomy. Results: Inspiratory pressure and tidal volumes achieved during the procedure were recorded. The median peak inspiratory pressure was 25 (standard deviation 4.4) cm H2O. There was no loss of tidal volume in 30 patients, a loss of less than 100 mL/breath in 27, and loss of more than 100 mL in 3 patients. A pro-seal LMA successfully maintained the airway and allowed adequate ventilation during per-cutaneous tracheostomy in all 60 patients. In all patients, fiber optic bronchoscopy through the pro-seal LMA provided a clear view of the cords and trachea and there was no laryngeal or tracheal soiling at any stage of the procedure. Conclusion: The pro-seal LMA provides a reliable airway and allows effective ventilation during percutaneous tracheostomy. The passage of a fiberscope through the pro-seal LMA and glottis is easy and provides a clear view of the upper trachea.