Browsing by Author "Sushmita Banerjee"

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Steroid Sensitive Nephrotic Syndrome: Revised Guidelines
(Springer, 2021) Aditi Sinha; Arvind Bagga; Sushmita Banerjee; Kirtisudha Mishra; Amarjeet Mehta; Indira Agarwal; Susan Uthup; Abhijeet Saha; Om Prakash Mishra
Justification: Steroid sensitive nephrotic syndrome (SSNS) is one of the most common chronic kidney diseases in children. These guidelines update the existing Indian Society of Pediatric Nephrology recommendations on its management. Objective: To frame revised guidelines on diagnosis, evaluation, management and supportive care of patients with the illness. Process: The guidelines combine evidence-based recommendations and expert opinion. Formulation of key questions was followed by review of literature and evaluation of evidence by experts in two face-to-face meetings. Recommendations: The initial statements provide advice for evaluation at onset and follow up and indications for kidney biopsy. Subsequent statements provide recommendations for management of the first episode of illness and of disease relapses. Recommendations on the use of immunosuppressive strategies in patients with frequent relapses and steroid dependence are accompanied by suggestions for step-wise approach and plan of monitoring. Guidance is also provided regarding the management of common complications including edema, hypovolemia and serious infections. Advice on immunization and transition of care is given. The revised guideline is intended to improve the management and outcomes of patients with SSNS, and provide directions for future research. © 2021, Indian Academy of Pediatrics.