Browsing by Author "T.N. Tiwari"

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Antifungal properties of Ocimum gratissimum essential oil (ethyl cinnamate chemotype)
(Elsevier, 2000) Nawal Kishore Dubey; T.N. Tiwari; Danielle Mandin; Hary Andriamboavonjy; Jean-Pierre Chaumont
Largely widespread in tropical countries, Ocimum gratissimum has been claimed for many uses in folk medicine. Recent research on its essential oils showed five chemotypes. An Indian chemotype, with a high level of ethyl cinnamate, presents, in vitro, an interesting spectrum of antifungal properties. (C) 2000 Elsevier Science B.V.
Antimycotic potency of some essential oils in the treatment of induced dermatomycosis of an experimental animal
(2003) T.N. Tiwari; J.P.N. Chansouria; N.K. Dubey
During screening of 20 essential oils against Epidermophyton floccosum and Microsporum gypseum, the test dermatophytes, the oils of Ocimum gratissimum and Trachyspermum ammi exhibited strong antidermatophytic properties. The ointments of the oils blocked dermatomycosis induced with guinea pigs, thereby indicating their efficacy as herbal treatments for the cure of dermatomycoses.
Cytotoxic activity of the essential oils of Trachyspermum ammi and Eupatorium cannabinum
(Indian Drug Manufacturers' Association, 1997) N.K. Dubey; N. Kishore; T.N. Tiwari; Lee Sook Young
[No abstract available]
Pharmacological evaluation of some bioactive plant products on albino rats.
(1998) T.N. Tiwari; J. Varma; N.K. Dubey; J.P. Chansouria; Z. Ali
The study comprises the pharmacological trials with essential oils of Caesulia axillaris, Ocimum gratissimum and Mentha arvensis which have shown strong antifungal property. The biochemical analysis of blood and serum of albino rats fed with the oil treated diet for sixty days exhibited nonanimal toxic nature of the oils. The study reveals the possibility of further exploitation of the oils as safe antifungal agents of plant origin.
Plumieride from Allamanda cathartica as an antidermatophytic agent
(2002) T.N. Tiwari; V.B. Pandey; N.K. Dubey
Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P388 mouse leukaemia cell line. Copyright © 2002 John Wiley & Sons, Ltd.
Ursolic acid - A cytotoxic constituent isolated from Allamanda cathartica linn
(Indian Drug Manufacturers' Association, 1998) T.N. Tiwari; N.K. Dubey; V.B. Pandey
Ursolic acid isolated from the leaves of Allamanda cathartica has been tested for its cytotoxicity against P388 lymphocytic leukemia cells. Its IC50 value has found to be 2.3 μg/ml. The structure elucidation of ursolic acid has been described.