Browsing by Author "Toru Takahashi"

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A tribute to nutrio-diabetologist; Shanti S. Rastogi MBBS, MD, FRCP, FICN, FICC
(Bentham Science Publishers, 2014) Ram B. Singh; Amrat K. Singh; Hideki Mori; Daniel Pella; Tapan K. Basu; Lech Ozimek; Shailendra K. Vajpeyee; Douglas W. Wilson; Fabien De Meester; Krasimira Hristova; Lekh Juneja; Sukhinder Kaur; Manohar Garg; Toru Takahashi; Adarsh Kumar; Rajiv Garg; Nirankar S. Neki; R.G. Singh; Sharad Rastogi
[No abstract available]
Development of a Functional Food Security for Parents for Transgenerational Epigenetic Health Promotion and Disease Prevention Among Offspring
(Elsevier, 2018) Ram B. Singh; Anil K. Chauhan; Ravi P. Singh; Meenakshi Singh; Sanjay Mishra; Fabien De Meester; Krasimira Hristova; Toru Takahashi; Jan Fedacko; Anna Gvozdjakova; Arunporn Itharat; Ekasit Onsaard; Douglas W. Wilson
Background: Noncommunicable diseases (NCDs) have become a worldwide problem due food security and lack of physical activity. The rapid increase may be due to interaction of genes/memes and environment, having adverse effects on the epigenome. A new package of nutrient-rich functional foods (FFs) or a package of micronutrients (based on healthy foods) and egg or soy bean milk, may protect against epigenetic inheritance, which is probably a safe strategy for protection from diseases. Methods: Discussion with colleagues in this field and website search. Results: Recent studies indicate that Mediterranean-style foods and multiple micronutrients are inversely associated with risk of NCDs; cardiovascular diseases, type 2 diabetes, and obesity later in adult life. Recommendations by UNICEF/WHO/UNU for pregnant women include 15 micronutrients likely to be administered during the antenatal period. Micronutrients supplementation is required in three different conditions, namely, nonpregnant, pregnant, and lactating women. As Mediterranean-style diets are rich in FFs, administration of these foods during pregnancy provides most of the aforementioned nutrients, which may be beneficial to mothers, as well as the fetus and offspring. A significant increase in body length was observed on administering a high-fat diet to pregnant mice, which remained across two generations of offspring. It could be an epigenetic inheritance of a growth-related factor in the offspring, reflecting reduced insulin sensitivity across two generations, and also providing a proof of epigenetic alterations in gene expression via altered tertiary structure of a DNA strand, without altering the DNA sequence. Conclusions: This approach may cause health promotion and disease prevention in the next generation. The idea of FF security for global health is important and practical. © 2018 Elsevier Inc. All rights reserved.
Dietary Fiber and Risk of Cardiovascular Diseases
(Elsevier Inc., 2017) Divya R. Gunashekar; Ram B. Singh; Mohammad A. Niaz; Anand R. Shewale; Toru Takahashi; Anil K. Chauhan; Ravi P. Singh
Mortality and morbidity due to heart diseases is decreasing in developed countries due to healthy diet and lifestyle, whereas in developing countries, it is rapidly increasing due to unhealthy diets and lifestyle. Healthy diets are rich in plant foods and majority of the plant foods are rich in fiber. Vegetables, whole grains, fruits, and legumes are rich sources of fibers. Soluble fibers have been considered more useful compared to insoluble fibers. Dietary fibers are known to have hypoglycemic, hypocholesterolemic, antioxidant, antiinflammatory, and antihypertensive effects indicating that fiber intake may be protective against cardiovascular diseases (CVDs), coronary artery disease (CAD), stroke, and hypertension, as well as diabetes. In a meta-analysis, 22 cohort study publications met inclusion criteria. Total dietary fiber intake, fiber subtypes, or fiber from food sources and primary events of CVDs or CAD were considered important. Total dietary fiber intake was inversely associated with risk of CVD including CAD. Observed heterogeneity between pooled studies for CVD and CAD were apparent. Insoluble fiber and fiber from cereal and vegetable sources were inversely associated with risk of CAD and CVD. Fruit fiber intake as part of Mediterranean style diet was also inversely associated with risk of CVD. It is possible that increased consumption of dietary fiber may be associated with a lower risk of both CVD and CAD. These results support the general recommendations to increase fiber intake for prevention of CVDs. The mechanism could be that fiber inhibit the absorption of fat from the gut but recently dietary fiber has been demonstrated to be beneficial for gut microbiome. The differing strengths of association by fiber type or source highlight the need for a better understanding of the mode of action of fiber components and the effects of fiber on other targets, which indirectly control CVDs. © 2017 Elsevier Inc. All rights reserved.
Functional food security for prevention of obesity and metabolic syndrome
(Elsevier, 2018) Sergey Chibisov; Mukta Singh; Ram B. Singh; Ghazi Halabi; Rie Horiuchi; Toru Takahashi
The world is still ignorant about the role of functional food security which depends on food diversity as well as on adequacy of nutrients. The nutrient adequacy was possibly abundant in the Paleolithic diet 40,000 years ago because of the diversity in food consumption patterns. Therefore, the increased prevalence of metabolic syndrome and the resultant type 2 diabetes, hypertension, and heart disease globally, may be the result of worldwide food security without much consideration for the adverse effects of Westernized type foods, sedentary behavior, and rapid rise in the epidemic of obesity. Further, evidence from prospective observational studies and clinical trials has converged to support the importance of individual nutrients, foods, and dietary patterns in the prevention and management of obesity and metabolic syndrome. The quality of dietary fats and carbohydrates consumed is more crucial than the quantity of these nutrients. Diets rich in whole grains, fruits, vegetables, legumes, nuts, moderate in alcohol consumption, and lower in refined grains, red/processed meats, and sugar-sweetened beverages have been demonstrated to reduce the risk of obesity and metabolic syndrome. Several healthful dietary patterns emphasizing the overall diet quality can be adapted to appropriate personal and cultural food preferences and calorie needs for weight control and management. Considerable progress has been made in developing and implementing evidence-based nutrition recommendations in developed countries, however, concerted global efforts and policies are warranted to alleviate regional disparities. More recent evidence has emphasized that food diversity and greater consumption of functional foods can cause a significant reduction in the epidemic of obesity and metabolic syndrome, resulting in health promotion. We therefore propose that food diversity by increasing traditional food consumption with a preference for functional foods, in conjunction with moderate physical activity, can protect the physiology and metabolism of the community, resulting in a decrease in the epidemic of obesity and an improvement in world health. © 2019 Elsevier Inc. All rights reserved.
Holistic approaches for health education and health promotion
(Nova Science Publishers, Inc., 2017) Arunporn Itharat; Toru Takahashi; R.G. Singh; R.B. Singh; Krisana Krisentu; Raima Lobenberg; Hiroshi Noguchi; Ibrahim Jantan; Telessy G. Istvan; Douglas W. Wilson; Sergey Shastun; H.S. Buttar; Galal Elkilany; Krasimira Hristova; Germaine Cornélissen; Laila Hussain; Ahmad Sulaeman; Mukta Singh; R.K. Srivastav
Modern approaches: moderate physical activity, a functional food-rich diet, reduction of body weight, control of blood pressure and blood lipids by drug therapy, cessation of tobacco and alcohol use, for health promotion and prevention of non-communicable diseases (NCDs) have only partial benefit on future risk of these diseases, despite the high health budget in high-income countries. Holistic approaches to health education and holistic health may provide better health and may be more successful in the prevention of cardiovascular diseases (CVDs) and other chronic diseases. There is evidence that psychosocial stress, late night sleep and late night eating, as well as sleep deprivation, deficiency of nutrients such as omega-3 fatty acids, vitamins and flavonoids can have adverse effects on brain-body mechanisms, resulting in obesity and insulin resistance, leading to CVDs and other chronic diseases. However, active prayer, kirtan krea, verbalization, yogasan and meditation, along with Mediterranean style-functional food-rich diet as well as nutraceuticals and herbs may be protective against NCDs. © 2017 Nova Science Publishers, Inc.
In memorium, Shanti S. Rastogi, MBBS, MD, FRCP, FICN, FICC
(Nova Science Publishers, Inc., 2016) Ram B. Singh; Amrat K. Singh; Hideki Mori; Daniel Pella; Tapan K. Basu; Lech Ozimek; Shailendra K. Vajpeyee; Douglas W. Wilson; Fabien de Meester; Krasimira Hristova; Lekh Juneja; Sukhinder Kaur; Manohar Garg; Toru Takahashi; Adarsh Kumar; Rajiv Garg; Nirankar S. Neki; R.G. Singh; Pawan K. Singal; Sharad Rastogi
[No abstract available]
Modernization of policy for food manufacturing and farming may be necessary for global health
(Elsevier, 2018) Ram B. Singh; Jagdish P. Sharma; Toru Takahashi; Lekh R. Juneja; Ronald R. Watson; Rukam S. Tomar; Mukta Singh; Poonam Jaglan; Meenakshi Singh; Ester Halmy; Anil K. Chauhan; Ekasit Onsaard
The major noncommunicable diseases (NCDs)-obesity, type 2 diabetes, cardiovascular disease, cancer, and chronic obstructive pulmonary diseases-are rapidly increasing in almost all countries and are now among the world’s biggest killers. NCDs are polygenic and multifactorial and pose a major challenge to economic development and urbanization being due to increased prosperity of populations with food security across the world. The contributing factors are multifaceted and complex, characterized with food production by farming and food manufacturing by the industry as well as by food prices determined by the governments. Other factors may be extensive advertisements by the food industry and inadequate legislation in labeling food contents. Health behavior related to population aging, urbanization, the globalization of trade and marketing, and the resulting progressive increase in unhealthy patterns of diets and eating also appear to be important. A change in policy aimed at manufacturing only slowly absorbed functional foods to be available at affordable price can increase the consumption of these foods. Plant breeding and genetic engineering should be used to develop new foods as a weapon to reduce the cost of expensive healthy foods such as walnuts and almonds as well as vegetables and fruits. © 2019 Elsevier Inc. All rights reserved.
The Singh’s Concept of Functional Foods and Functional Farming (4 F) for World Health
(Elsevier, 2018) Toru Takahashi; Ram B. Singh; Sergey Chibisov; Rukam S. Tomar; Tanya Charkrabarti; Anil K. Chauhan; Ekasit Onsaard; Wiriya Phomkong; Hilton Chaves; Mukta Singh; Ratan Srivastav; Manushi Srivastav; Rana G. Singh; Poonam Jaglan
Economic development is associated with increased consumption of saturated fat, refined starchy foods with excess of salt and sugar, manufactured by the food industry, in conjunction with physical inactivity that are responsible for obesity and related noncommunicable (NCDs). However, functional foods characterized with traditional whole grains; wheat, grams, beans with fruits, vegetables, legumes, nuts, olive oil, mustard oil/canola oil have been found to be protective against NCDs. Obesity is one of the biggest risk factors of NCDs; cardiovascular diseases; hypertension, coronary artery disease, strokes, heart failure, and other types of chronic diseases, such as type 2 diabetes mellitus, cancer, chronic respiratory diseases, bone and joint diseases, and neurodegenerative diseases. There is a prospect to develop an international unanimity on how to forestall undernutrition, via increased food availability, through Functional Foods and Functional Farming (4 F), so that there is no rise in human vulnerability to obesity and NCDs. Previous attempts with food security via energy-rich products such as manufactured foods as well as food produced via farming (more energy, less nutrients) have resulted into increased burden of obesity. It has been demonstrated that an Indo-Mediterranean dietary pattern characterized with functional foods; whole grains, vegetables, fruits, nuts, and fish in conjunction with olive oil plus mustard or canola oil can help the prevention of various diseases. Further attempts must be made to provide nutrient rich feedstock to animals and birds and soil for growth of foods to develop new functional foods, such as Sim’s egg, to increase food availability. © 2019 Elsevier Inc. All rights reserved.
The thailand declaration of the international college of nutrition: Can functional foods and functional crops decrease the risk of chronic diseases and provide wellness?
(Nova Science Publishers, Inc., 2017) Wiriya Phomkong; Ekasit Onsaard; Dherapol Bansiddhi; R.B. Singh; Buncha Ooraikul; Arunporn Itharat; Fabien De Meester; Jagdish P. Sharma; Rana G. Singh; Usha Singh; Harpal S. Buttar; Istvan G. Telessy; Toru Takahashi; Lech Ozimek; Jae-Kwan Hwang; Kohei Oda; Douglas W. Wilson
There is evidence that optimal nutrition is fundamental to human health and in the prevention of non-communicable diseases (NCDs) later in adult life. The identification, production and consumption of functional foods worldwide can increase health benefits for all who can access and afford such foods subject to advice from nutritionists. Recent meetings organized by the health agencies, give a crucial opportunity to make nutrition a central part of the post-2015 sustainable human and agricultural development agenda. The aim of discussions in these meetings was to provide functional crops and foods to achieve optimal health by prevention of NCDs. It is possible that these efforts might ensure that the goals and targets set in the agenda are adequate to address the many challenges of global undernutrition as well as obesity which are major risk factors of NCDs. In many developing and middle income countries, food security provided by the governments, in one sense understandably, gave least consideration to functional foods supply and the prevention of obesity and metabolic syndrome, resulting in to emergence of NCDs. The Thailand Declaration reiterates commitments to eradicate hunger and undernutrition as well as over-nutrition, and to increase investments in effective interventions such as designer foods and designer crops. However, in planning coherent policies, our past experience on rapidly absorbed, energy-rich processed foods should be taken into account while developing sustainable food systems. The food industry should be educated to exploit the expertise of food scientists and health professionals in designing functional foods taking cognizance of manufacturing and processing. Similarly, agriculture scientists may be actively involved in educating farmers so as to grow cash crops providing functional foods. The aim should be to achieve an increase in the availability of functional foods to an extent, or by a policy, by which such foods are available to poor people at affordable cost to prevent hunger and undernutrition and related diseases as well as NCDs. In addition our efforts might help in developing an international consensus on how to approach the development of new designer foods by farmers and the food industry to produce low-glycemic-index foods. Such efforts may establish an international framework for the prevention of NCDs, so that human susceptibility to these diseases is substantially diminished. © 2018, Nova Science Publishers, Inc.. All rights reserved.