Browsing by Author "Victor Chaplygin"

Now showing 1 - 3 of 3

Phenolic Compounds of the Medicinal Plants in an Anthropogenically Transformed Environment
(Multidisciplinary Digital Publishing Institute (MDPI), 2023) Natalya Vinogradova; Elena Vinogradova; Victor Chaplygin; Saglara Mandzhieva; Pradeep Kumar; Vishnu D. Rajput; Tatiana Minkina; Chandra Shekhar Seth; Marina Burachevskaya; Dionise Lysenko; Rupesh Kumar Singh
In this article, the impact of an anthropogenically transformed environment on the content of pharmaceutically valuable biologically active compounds in medicinal plants is analyzed. The studied biologically active substances included phenolic compounds (flavonoids, anthocyanins, tannins, and phenolic acids). The number of transmissible forms of heavy metals (HMs), including cadmium, lead, and mercury, were discharged from factories that are present in the soil. Plants uptake these toxic metals from the soil. HM causes changes in the activity of the several enzymes such as phenylalanine ammonia lyase (PAL), chalcone synthase (CHS), chalcone isomerase (CHI) and other enzymes. These enzymes play an important role in biosynthesis of phenolic compounds in medicinal plants. It has been demonstrated that plant materials possess high antioxidant potential due to their high phenolic content. As a result, the present review discusses a thorough investigation of anthropogenically transformed environment effects on the quantity of pharmaceutically valuable phenolic compounds in medicinal plants. © 2023 by the authors.
Role of plant secondary metabolites in defence and transcriptional regulation in response to biotic stress
(Elsevier B.V., 2023) Anjali; Sumit Kumar; Tulasi Korra; Rajneesh Thakur; R. Arutselvan; Abhijeet Shankar Kashyap; Yasser Nehela; Victor Chaplygin; Tatiana Minkina; Chetan Keswani
Secondary metabolites in plants have been recognized as a novel basis of potential bio-pesticides, paving the way for their use in sustainable agriculture. Plant secondary metabolites have pivotal roles in plant-pathogen interactions. Some important secondary metabolites of plants are terpenoids, flavanols, flavones, etc., are stress-inducible phytochemicals playing an important role in plant immune response development. Pathogen enters into host cell, multiply and utilise the biological mechanism of plants, causing a hazard to world food assembly. Under stressed circumstances, plants evolve a powerful and intricate system of growth and defensive action. On the other hand, transcription factors (TFs) assist host plants to counter adverse environments by acting as mediators of stress signal and regulating the stress-responsive gene expression. The transcriptional and post-transcriptional manipulation of transcriptional factors is capable of aid in molecular breeding and genetic modification meant for improved secondary metabolite synthesis. Although the presence of numerous secondary metabolites has been established in plant life, very slight is known about their interaction with pathogens and the specific mechanisms involved in leading to plant immunity. Chemical pesticides are wreaking havoc on our environment. As a consequence, environmental-friendly alternatives to disease management, like plant-based metabolites, should be explored. In this appraisal, we have reviewed plant secondary metabolites in relation to pathogens, their contribution to innate immunity, mechanism of action, and regulation of TFs in response to combating plant infections in an eco-friendly approach. © 2023 The Authors
The Content of Heavy Metals in Medicinal Plants in Various Environmental Conditions: A Review
(MDPI, 2023) Natalya Vinogradova; Alexander Glukhov; Victor Chaplygin; Pradeep Kumar; Saglara Mandzhieva; Tatiana Minkina; Vishnu D. Rajput
Nowadays people are becoming poisoned through the consumption of herbal remedies that comprise heavy metals (HMs) worldwide. It is possible for HMs to be present in pharmaceutical herb materials coming from anthropogenic activities like agriculture, industrial waste, and natural sources. In various ethnic groups, there is evidence that contaminants were purposefully added in the belief that they had some sort of therapeutic benefit. HM toxicity of medicinal plant products has been linked to a wide range of adverse health effects, causing dysfunction of the liver, kidney, and heart, and even death. Natural plant-based products established around the world have progressed to the point that they now combine a variety of synthetic products for their purported medical benefits. This assessment focuses on the impacts of HMs on plants, sources of HMs, herbal sample collection, and identification techniques, especially in medicinal plant samples. At the same time, it focuses on the sociocultural applications of HMs as well as the dangers associated with their usage in conventional therapies. It is necessary to implement appropriate regulation and monitoring systems for natural supplements due to the prevalence of hazardous HMs. © 2023 by the authors.