Browsing by Author "Vivek Gupta"

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Delta variant SARS-CoV-2 infections in pediatric cases during the second wave in India
(Elsevier Ltd, 2022) Pragya D. Yadav; Gunjan Kumar; Aparna Mukherjee; Dimpal A. Nyayanit; Anita M. Shete; Rima R. Sahay; Abhinendra Kumar; Triparna Majumdar; Savita Patil; Priyanka Pandit; Yash Joshi; Manisha Dudhmal; Samiran Panda; Lokesh Kumar Sharma; Kala Yadav Ml; Jayanthi Shastri; Mayank Gangwar; Ashok Munivenkattapa; Varsha Potdar; K. Nagamani; Kapil Goyal; Ravisekhar Gadepalli; Maria Thomas; Suruchi Shukla; P. Nagraj; Vivek Gupta; Gaurav Dalela; Nawaz Umar; Sweety M. Patel
Background: During October 2020, Delta variant was detected for the first time in India and rampantly spread across the globe. It also led to second wave of pandemic in India which affected millions of people. However, there is limited information pertaining to the SARS-CoV-2 strain infecting the children in India. Methods: Here, we assessed the SARS-CoV-2 lineages circulating in the pediatric population of India during the second wave of the pandemic. Clinical and demographic details linked with the nasopharyngeal/oropharyngeal swabs (NPS/OPS) collected from SARS-CoV-2 cases (n = 583) aged 0–18 year and tested positive by real-time RT-PCR were retrieved from March to June 2021. Results: Symptoms were reported among 37.2% of patients and 14.8% reported to be hospitalized. The E gene CT value had significant statistical difference at the point of sample collection when compared to that observed in the sequencing laboratory. Out of these 512 sequences 372 were VOCs, 51 were VOIs. Most common lineages observed were Delta, followed by Kappa, Alpha and B.1.36, seen in 65.82%, 9.96%, 6.83% and 4.68%, respectively in the study population. Conclusion: Overall, it was observed that Delta strain was the leading cause of SARS-CoV-2 infection in Indian children during the second wave of the pandemic. We emphasize on the need of continuous genomic surveillance in SARS-CoV-2 infection even amongst children. © 2022
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
(Taylor and Francis Ltd., 2021) Daniel J. Klionsky; Amal Kamal Abdel-Aziz; Sara Abdelfatah; Mahmoud Abdellatif; Asghar Abdoli; Steffen Abel; Hagai Abeliovich; Marie H. Abildgaard; Yakubu Princely Abudu; Abraham Acevedo-Arozena; Iannis E. Adamopoulos; Khosrow Adeli; Timon E. Adolph; Annagrazia Adornetto; Elma Aflaki; Galila Agam; Anupam Agarwal; Bharat B. Aggarwal; Maria Agnello; Patrizia Agostinis; Javed N. Agrewala; Alexander Agrotis; Patricia V. Aguilar; S. Tariq Ahmad; Zubair M. Ahmed; Ulises Ahumada-Castro; Sonja Aits; Shu Aizawa; Yunus Akkoc; Tonia Akoumianaki; Hafize Aysin Akpinar; Ahmed M. Al-Abd; Lina Al-Akra; Abeer Al-Gharaibeh; Moulay A. Alaoui-Jamali; Simon Alberti; Elísabet Alcocer-Gómez; Cristiano Alessandri; Muhammad Ali; M. Abdul Alim Al-Bari; Saeb Aliwaini; Javad Alizadeh; Eugènia Almacellas; Alexandru Almasan; Alicia Alonso; Guillermo D. Alonso; Nihal Altan-Bonnet; Dario C. Altieri; Élida M. C. Álvarez; Sara Alves; Cristine Alves da Costa; Mazen M. Alzaharna; Marialaura Amadio; Consuelo Amantini; Cristina Amaral; Susanna Ambrosio; Amal O. Amer; Veena Ammanathan; Zhenyi An; Stig U. Andersen; Shaida A. Andrabi; Magaiver Andrade-Silva; Allen M. Andres; Sabrina Angelini; David Ann; Uche C. Anozie; Mohammad Y. Ansari; Pedro Antas; Adam Antebi; Zuriñe Antón; Tahira Anwar; Lionel Apetoh; Nadezda Apostolova; Toshiyuki Araki; Yasuhiro Araki; Kohei Arasaki; Wagner L. Araújo; Jun Araya; Catherine Arden; Maria-Angeles Arévalo; Sandro Arguelles; Esperanza Arias; Jyothi Arikkath; Hirokazu Arimoto; Aileen R. Ariosa; Darius Armstrong-James; Laetitia Arnauné-Pelloquin; Angeles Aroca; Daniela S. Arroyo; Ivica Arsov; Rubén Artero; Dalia Maria Lucia Asaro; Michael Aschner; Milad Ashrafizadeh; Osnat Ashur-Fabian; Atanas G. Atanasov; Alicia K. Au; Patrick Auberger; Holger W. Auner; Laure Aurelian; Riccardo Autelli; Laura Avagliano; Yenniffer Ávalos; Sanja Aveic; Célia Alexandra Aveleira; Tamar Avin-Wittenberg; Yucel Aydin; Scott Ayton; Srinivas Ayyadevara; Maria Azzopardi; Misuzu Baba; Jonathan M. Backer; Steven K. Backues; Dong-Hun Bae; Ok-Nam Bae; Soo Han Bae; Eric H. Baehrecke; Ahruem Baek; Seung-Hoon Baek; Sung Hee Baek; Giacinto Bagetta; Agnieszka Bagniewska-Zadworna; Hua Bai; Jie Bai; Xiyuan Bai; Yidong Bai; Nandadulal Bairagi; Shounak Baksi; Teresa Balbi; Cosima T. Baldari; Walter Balduini; Andrea Ballabio; Maria Ballester; Salma Balazadeh; Rena Balzan; Rina Bandopadhyay; Sreeparna Banerjee; Sulagna Banerjee; Ágnes Bánréti; Yan Bao; Mauricio S. Baptista; Alessandra Baracca; Cristiana Barbati; Ariadna Bargiela; Daniela Barilà; Peter G. Barlow; Sami J. Barmada; Esther Barreiro; George E. Barreto; Jiri Bartek; Bonnie Bartel; Alberto Bartolome; Gaurav R. Barve; Suresh H. Basagoudanavar; Diane C. Bassham; Robert C. Bast; Alakananda Basu; Henri Batoko; Isabella Batten; Etienne E. Baulieu; Bradley L. Baumgarner; Jagadeesh Bayry; Rupert Beale; Isabelle Beau; Florian Beaumatin; Luiz R.G. Bechara; George R. Beck; Michael F. Beers; Jakob Begun; Christian Behrends; Georg M.N. Behrens; Roberto Bei; Eloy Bejarano; Shai Bel; Christian Behl; Amine Belaid; Naïma Belgareh-Touzé; Cristina Bellarosa; Francesca Belleudi; Melissa Belló Pérez; Raquel Bello-Morales; Jackeline Soares de Oliveira Beltran; Sebastián Beltran; Doris Mangiaracina Benbrook; Mykolas Bendorius; Bruno A. Benitez; Irene Benito-Cuesta; Julien Bensalem; Martin W. Berchtold; Sabina Berezowska; Daniele Bergamaschi; Matteo Bergami; Andreas Bergmann; Laura Berliocchi; Clarisse Berlioz-Torrent; Amélie Bernard; Lionel Berthoux; Cagri G. Besirli; Sebastien Besteiro; Virginie M. Betin; Rudi Beyaert; Jelena S. Bezbradica; Kiran Bhaskar; Ingrid Bhatia-Kissova; Resham Bhattacharya; Sujoy Bhattacharya; Shalmoli Bhattacharyya; Md. Shenuarin Bhuiyan; Sujit Kumar Bhutia; Lanrong Bi; Xiaolin Bi; Trevor J. Biden; Krikor Bijian; Viktor A. Billes; Nadine Binart; Claudia Bincoletto; Asa B. Birgisdottir; Geir Bjorkoy; Gonzalo Blanco; Ana Blas-Garcia; Janusz Blasiak; Robert Blomgran; Klas Blomgren; Janice S. Blum; Emilio Boada-Romero; Mirta Boban; Kathleen Boesze-Battaglia; Philippe Boeuf; Barry Boland; Pascale Bomont; Paolo Bonaldo; Srinivasa Reddy Bonam; Laura Bonfili; Juan S. Bonifacino; Brian A. Boone; Martin D. Bootman; Matteo Bordi; Christoph Borner; Beat C. Bornhauser; Gautam Borthakur; Jürgen Bosch; Santanu Bose; Luis M. Botana; Juan Botas; Chantal M. Boulanger; Michael E. Boulton; Mathieu Bourdenx; Benjamin Bourgeois; Nollaig M. Bourke; Guilhem Bousquet; Patricia Boya; Peter V. Bozhkov; Luiz H. M. Bozi; Tolga O. Bozkurt; Doug E. Brackney; Christian H. Brandts; Ralf J. Braun; Gerhard H. Braus; Roberto Bravo-Sagua; José M. Bravo-San Pedro; Patrick Brest; Marie-Agnès Bringer; Alfredo Briones-Herrera; V. Courtney Broaddus; Peter Brodersen; Jeffrey L. Brodsky; Steven L. Brody; Paola G. Bronson; Jeff M. Bronstein; Carolyn N. Brown; Rhoderick E. Brown; Patricia C. Brum; John H. Brumell; Nicola Brunetti-Pierri; Daniele Bruno; Robert J. Bryson-Richardson; Cecilia Bucci; Carmen Buchrieser; Marta Bueno; Laura Elisa Buitrago-Molina; Simone Buraschi; Shilpa Buch; J. Ross Buchan; Erin M. Buckingham; Hikmet Budak; Mauricio Budini; Geert Bultynck; Florin Burada; Joseph R. Burgoyne; M. Isabel Burón; Victor Bustos; Sabrina Büttner; Elena Butturini; Aaron Byrd; Isabel Cabas; Sandra Cabrera-Benitez; Ken Cadwell; Jingjing Cai; Lu Cai; Qian Cai; Montserrat Cairó; Jose A. Calbet; Guy A. Caldwell; Kim A. Caldwell; Jarrod A. Call; Riccardo Calvani; Ana C. Calvo; Miguel Calvo-Rubio Barrera; Niels OS Camara; Jacques H. Camonis; Nadine Camougrand; Michelangelo Campanella; Edward M. Campbell; François-Xavier Campbell-Valois; Silvia Campello; Ilaria Campesi; Juliane C. Campos; Olivier Camuzard; Jorge Cancino; Danilo Candido de Almeida; Laura Canesi; Isabella Caniggia; Barbara Canonico; Carles Cantí; Bin Cao; Michele Caraglia; Beatriz Caramés; Evie H. Carchman; Elena Cardenal-Muñoz; Cesar Cardenas; Luis Cardenas; Sandra M. Cardoso; Jennifer S. Carew; Georges F. Carle; Gillian Carleton; Silvia Carloni; Didac Carmona-Gutierrez; Leticia A. Carneiro; Oliana Carnevali; Julian M. Carosi; Serena Carra; Alice Carrier; Lucie Carrier; Bernadette Carroll; A. Brent Carter; Andreia Neves Carvalho; Magali Casanova; Caty Casas; Josefina Casas; Chiara Cassioli; Eliseo F. Castillo; Karen Castillo; Sonia Castillo-Lluva; Francesca Castoldi; Marco Castori; Ariel F. Castro; Margarida Castro-Caldas; Javier Castro-Hernandez; Susana Castro-Obregon; Sergio D. Catz; Claudia Cavadas; Federica Cavaliere; Gabriella Cavallini; Maria Cavinato; Maria L. Cayuela; Paula Cebollada Rica; Valentina Cecarini; Francesco Cecconi; Marzanna Cechowska-Pasko; Simone Cenci; Victòria Ceperuelo-Mallafré; João J. Cerqueira; Janete M. Cerutti; Davide Cervia; Vildan Bozok Cetintas; Silvia Cetrullo; Han-Jung Chae; Andrei S. Chagin; Chee-Yin Chai; Gopal Chakrabarti; Oishee Chakrabarti; Tapas Chakraborty; Trinad Chakraborty; Mounia Chami; Georgios Chamilos; David W. Chan; Edmond Y. W. Chan; Edward D. Chan; H.Y. Edwin Chan; Helen H. Chan; Hung Chan; Matthew T.V. Chan; Yau Sang Chan; Partha K. Chandra; Chih-Peng Chang; Chunmei Chang; Hao-Chun Chang; Kai Chang; Jie Chao; Tracey Chapman; Nicolas Charlet-Berguerand; Samrat Chatterjee; Shail K. Chaube; Anu Chaudhary; Santosh Chauhan; Edward Chaum; Frédéric Checler; Michael E. Cheetham; Chang-Shi Chen; Guang-Chao Chen; Jian-Fu Chen; Liam L. Chen; Leilei Chen; Lin Chen; Mingliang Chen; Mu-Kuan Chen; Ning Chen; Quan Chen; Ruey-Hwa Chen; Shi Chen; Wei Chen; Weiqiang Chen; Xin-Ming Chen; Xiong-Wen Chen; Xu Chen; Yan Chen; Ye-Guang Chen; Yingyu Chen; Yongqiang Chen; Yu-Jen Chen; Yue-Qin Chen; Zhefan Stephen Chen; Zhi Chen; Zhi-Hua Chen; Zhijian J. Chen; Zhixiang Chen; Hanhua Cheng; Jun Cheng; Shi-Yuan Cheng; Wei Cheng; Xiaodong Cheng; Xiu-Tang Cheng; Yiyun Cheng; Zhiyong Cheng; Zhong Chen; Heesun Cheong; Jit Kong Cheong; Boris V. Chernyak; Sara Cherry; Chi Fai Randy Cheung; Chun Hei Antonio Cheung; King-Ho Cheung; Eric Chevet; Richard J. Chi; Alan Kwok Shing Chiang; Ferdinando Chiaradonna; Roberto Chiarelli; Mario Chiariello; Nathalia Chica; Susanna Chiocca; Mario Chiong; Shih-Hwa Chiou; Abhilash I. Chiramel; Valerio Chiurchiù; Dong-Hyung Cho; Seong-Kyu Choe; Augustine M.K. Choi; Mary E. Choi; Kamalika Roy Choudhury; Norman S. Chow; Charleen T. Chu; Jason P. Chua; John Jia En Chua; Hyewon Chung; Kin Pan Chung; Seockhoon Chung; So-Hyang Chung; Yuen-Li Chung; Valentina Cianfanelli; Iwona A. Ciechomska; Mariana Cifuentes; Laura Cinque; Sebahattin Cirak; Mara Cirone; Michael J. Clague; Robert Clarke; Emilio Clementi; Eliana M. Coccia; Patrice Codogno; Ehud Cohen; Mickael M. Cohen; Tania Colasanti; Fiorella Colasuonno; Robert A. Colbert; Anna Colell; Miodrag Čolić; Nuria S. Coll; Mark O. Collins; María I. Colombo; Daniel A. Colón-Ramos; Lydie Combaret; Sergio Comincini; Márcia R. Cominetti; Antonella Consiglio; Andrea Conte; Fabrizio Conti; Viorica Raluca Contu; Mark R. Cookson; Kevin M. Coombs; Isabelle Coppens; Maria Tiziana Corasaniti; Dale P. Corkery; Nils Cordes; Katia Cortese; Maria do Carmo Costa; Sarah Costantino; Paola Costelli; Ana Coto-Montes; Peter J. Crack; Jose L. Crespo; Alfredo Criollo; Valeria Crippa; Riccardo Cristofani; Tamas Csizmadia; Antonio Cuadrado; Bing Cui; Jun Cui; Yixian Cui; Yong Cui; Emmanuel Culetto; Andrea C. Cumino; Andrey V. Cybulsky; Mark J. Czaja; Stanislaw J. Czuczwar; Stefania D’Adamo; Marcello D’Amelio; Daniela D’Arcangelo; Andrew C. D’Lugos; Gabriella D’Orazi; James A. da Silva; Hormos Salimi Dafsari; Ruben K. Dagda; Yasin Dagdas; Maria Daglia; Xiaoxia Dai; Yun Dai; Yuyuan Dai; Jessica Dal Col; Paul Dalhaimer; Luisa Dalla Valle; Tobias Dallenga; Guillaume Dalmasso; Markus Damme; Ilaria Dando; Nico P. Dantuma; April L. Darling; Hiranmoy Das; Srinivasan Dasarathy; Santosh K. Dasari; Srikanta Dash; Oliver Daumke; Adrian N. Dauphinee; Jeffrey S. Davies; Valeria A. Dávila; Roger J. Davis; Tanja Davis; Sharadha Dayalan Naidu; Francesca De Amicis; Karolien De Bosscher; Francesca De Felice; Lucia De Franceschi; Chiara De Leonibus; Mayara G. de Mattos Barbosa; Guido R.Y. De Meyer; Angelo De Milito; Cosimo De Nunzio; Clara De Palma; Mauro De Santi; Claudio De Virgilio; Daniela De Zio; Jayanta Debnath; Brian J. DeBosch; Jean-Paul Decuypere; Mark A. Deehan; Gianluca Deflorian; James DeGregori; Benjamin Dehay; Gabriel Del Rio; Joe R. Delaney; Lea M. D. Delbridge; Elizabeth Delorme-Axford; M. Victoria Delpino; Francesca Demarchi; Vilma Dembitz; Nicholas D. Demers; Hongbin Deng; Zhiqiang Deng; Joern Dengjel; Paul Dent; Donna Denton; Melvin L. DePamphilis; Channing J. Der; Vojo Deretic; Albert Descoteaux; Laura Devis; Sushil Devkota; Olivier Devuyst; Grant Dewson; Mahendiran Dharmasivam; Rohan Dhiman; Diego di Bernardo; Manlio Di Cristina; Fabio Di Domenico; Pietro Di Fazio; Alessio Di Fonzo; Giovanni Di Guardo; Gianni M. Di Guglielmo; Luca Di Leo; Chiara Di Malta; Alessia Di Nardo; Martina Di Rienzo; Federica Di Sano; George Diallinas; Jiajie Diao; Guillermo Diaz-Araya; Inés Díaz-Laviada; Jared M. Dickinson; Marc Diederich; Mélanie Dieudé; Ivan Dikic; Shiping Ding; Wen-Xing Ding; Luciana Dini; Jelena Dinić; Miroslav Dinic; Albena T. Dinkova-Kostova; Marc S. Dionne; Jörg H.W. Distler; Abhinav Diwan; Ian M.C. Dixon; Mojgan Djavaheri-Mergny; Ina Dobrinski; Oxana Dobrovinskaya; Radek Dobrowolski; Renwick C.J. Dobson; Jelena Đokić; Serap Dokmeci Emre; Massimo Donadelli; Bo Dong; Xiaonan Dong; Zhiwu Dong; Gerald W. Dorn II; Volker Dotsch; Huan Dou; Juan Dou; Moataz Dowaidar; Sami Dridi; Liat Drucker; Ailian Du; Caigan Du; Guangwei Du; Hai-Ning Du; Li-Lin Du; André du Toit; Shao-Bin Duan; Xiaoqiong Duan; Sónia P. Duarte; Anna Dubrovska; Elaine A. Dunlop; Nicolas Dupont; Raúl V. Durán; Bilikere S. Dwarakanath; Sergey A. Dyshlovoy; Darius Ebrahimi-Fakhari; Leopold Eckhart; Charles L. Edelstein; Thomas Efferth; Eftekhar Eftekharpour; Ludwig Eichinger; Nabil Eid; Tobias Eisenberg; N. Tony Eissa; Sanaa Eissa; Miriam Ejarque; Abdeljabar El Andaloussi; Nazira El-Hage; Shahenda El-Naggar; Anna Maria Eleuteri; Eman S. El-Shafey; Mohamed Elgendy; Aristides G. Eliopoulos; María M. Elizalde; Philip M. Elks; Hans-Peter Elsasser; Eslam S. Elsherbiny; Brooke M. Emerling; N. C. Tolga Emre; Christina H. Eng; Nikolai Engedal; Anna-Mart Engelbrecht; Agnete S.T. Engelsen; Jorrit M. Enserink; Ricardo Escalante; Audrey Esclatine; Mafalda Escobar-Henriques; Eeva-Liisa Eskelinen; Lucile Espert; Makandjou-Ola Eusebio; Gemma Fabrias; Cinzia Fabrizi; Antonio Facchiano; Francesco Facchiano; Bengt Fadeel; Claudio Fader; Alex C. Faesen; W. Douglas Fairlie; Alberto Falcó; Bjorn H. Falkenburger; Daping Fan; Jie Fan; Yanbo Fan; Evandro F. Fang; Yanshan Fang; Yognqi Fang; Manolis Fanto; Tamar Farfel-Becker; Mathias Faure; Gholamreza Fazeli; Anthony O. Fedele; Arthur M. Feldman; Du Feng; Jiachun Feng; Lifeng Feng; Yibin Feng; Yuchen Feng; Wei Feng; Thais Fenz Araujo; Thomas A. Ferguson; Álvaro F. Fernández; Jose C. Fernandez-Checa; Sonia Fernández-Veledo; Alisdair R. Fernie; Anthony W. Ferrante; Alessandra Ferraresi; Merari F. Ferrari; Julio C.B. Ferreira; Susan Ferro-Novick; Antonio Figueras; Riccardo Filadi; Nicoletta Filigheddu; Eduardo Filippi-Chiela; Giuseppe Filomeni; Gian Maria Fimia; Vittorio Fineschi; Francesca Finetti; Steven Finkbeiner; Edward A. Fisher; Paul B. Fisher; Flavio Flamigni; Steven J. Fliesler; Trude H. Flo; Ida Florance; Oliver Florey; Tullio Florio; Erika Fodor; Carlo Follo; Edward A. Fon; Antonella Forlino; Francesco Fornai; Paola Fortini; Anna Fracassi; Alessandro Fraldi; Brunella Franco; Rodrigo Franco; Flavia Franconi; Lisa B. Frankel; Scott L. Friedman; Leopold F. Fröhlich; Gema Frühbeck; Jose M. Fuentes; Yukio Fujiki; Naonobu Fujita; Yuuki Fujiwara; Mitsunori Fukuda; Simone Fulda; Luc Furic; Norihiko Furuya; Carmela Fusco; Michaela U. Gack; Lidia Gaffke; Sehamuddin Galadari; Alessia Galasso; Maria F. Galindo; Sachith Gallolu Kankanamalage; Lorenzo Galluzzi; Vincent Galy; Noor Gammoh; Boyi Gan; Ian G. Ganley; Feng Gao; Hui Gao; Minghui Gao; Ping Gao; Shou-Jiang Gao; Wentao Gao; Xiaobo Gao; Ana Garcera; Maria Noé Garcia; Verónica E. Garcia; Francisco García-Del Portillo; Vega Garcia-Escudero; Aracely Garcia-Garcia; Marina Garcia-Macia; Diana García-Moreno; Carmen Garcia-Ruiz; Patricia García-Sanz; Abhishek D. Garg; Ricardo Gargini; Tina Garofalo; Robert F. Garry; Nils C. Gassen; Damian Gatica; Liang Ge; Wanzhong Ge; Ruth Geiss-Friedlander; Cecilia Gelfi; Pascal Genschik; Ian E. Gentle; Valeria Gerbino; Christoph Gerhardt; Kyla Germain; Marc Germain; David A. Gewirtz; Elham Ghasemipour Afshar; Saeid Ghavami; Alessandra Ghigo; Manosij Ghosh; Georgios Giamas; Claudia Giampietri; Alexandra Giatromanolaki; Gary E. Gibson; Spencer B. Gibson; Vanessa Ginet; Edward Giniger; Carlotta Giorgi; Henrique Girao; Stephen E. Girardin; Mridhula Giridharan; Sandy Giuliano; Cecilia Giulivi; Sylvie Giuriato; Julien Giustiniani; Alexander Gluschko; Veit Goder; Alexander Goginashvili; Jakub Golab; David C. Goldstone; Anna Golebiewska; Luciana R. Gomes; Rodrigo Gomez; Rubén Gómez-Sánchez; Maria Catalina Gomez-Puerto; Raquel Gomez-Sintes; Qingqiu Gong; Felix M. Goni; Javier González-Gallego; Tomas Gonzalez-Hernandez; Rosa A. Gonzalez-Polo; Jose A. Gonzalez-Reyes; Patricia González-Rodríguez; Ing Swie Goping; Marina S. Gorbatyuk; Nikolai V. Gorbunov; Kıvanç Görgülü; Roxana M. Gorojod; Sharon M. Gorski; Sandro Goruppi; Cecilia Gotor; Roberta A. Gottlieb; Illana Gozes; Devrim Gozuacik; Martin Graef; Markus H. Gräler; Veronica Granatiero; Daniel Grasso; Joshua P. Gray; Douglas R. Green; Alexander Greenhough; Stephen L. Gregory; Edward F. Griffin; Mark W. Grinstaff; Frederic Gros; Charles Grose; Angelina S. Gross; Florian Gruber; Paolo Grumati; Tilman Grune; Xueyan Gu; Jun-Lin Guan; Carlos M. Guardia; Kishore Guda; Flora Guerra; Consuelo Guerri; Prasun Guha; Carlos Guillén; Shashi Gujar; Anna Gukovskaya; Ilya Gukovsky; Jan Gunst; Andreas Günther; Anyonya R. Guntur; Chuanyong Guo; Chun Guo; Hongqing Guo; Lian-Wang Guo; Ming Guo; Pawan Gupta; Shashi Kumar Gupta; Swapnil Gupta; Veer Bala Gupta; Vivek Gupta; Asa B. Gustafsson; David D. Gutterman; Ranjitha H.B; Annakaisa Haapasalo; James E. Haber; Aleksandra Hać; Shinji Hadano; Anders J. Hafrén; Mansour Haidar; Belinda S. Hall; Gunnel Halldén; Anne Hamacher-Brady; Andrea Hamann; Maho Hamasaki; Weidong Han; Malene Hansen; Phyllis I. Hanson; Zijian Hao; Masaru Harada; Ljubica Harhaji-Trajkovic; Nirmala Hariharan; Nigil Haroon; James Harris; Takafumi Hasegawa; Noor Hasima Nagoor; Jeffrey A. Haspel; Volker Haucke; Wayne D. Hawkins; Bruce A. Hay; Cole M. Haynes; Soren B. Hayrabedyan; Thomas S. Hays; Congcong He; Qin He; Rong-Rong He; You-Wen He; Yu-Ying He; Yasser Heakal; Alexander M. Heberle; J. Fielding Hejtmancik; Gudmundur Vignir Helgason; Vanessa Henkel; Marc Herb; Alexander Hergovich; Anna Herman-Antosiewicz; Agustín Hernández; Carlos Hernandez; Sergio Hernandez-Diaz; Virginia Hernandez-Gea; Amaury Herpin; Judit Herreros; Javier H. Hervás; Daniel Hesselson; Claudio Hetz; Volker T. Heussler; Yujiro Higuchi; Sabine Hilfiker; Joseph A. Hill; William S. Hlavacek; Emmanuel A. Ho; Idy H.T. Ho; Philip Wing-Lok Ho; Shu-Leong Ho; Wan Yun Ho; G. Aaron Hobbs; Mark Hochstrasser; Peter H.M. Hoet; Daniel Hofius; Paul Hofman; Annika Höhn; Carina I. Holmberg; Jose R. Hombrebueno; Chang-Won Hong Yi-Ren Hong; Lora V. Hooper; Thorsten Hoppe; Rastislav Horos; Yujin Hoshida; I-Lun Hsin; Hsin-Yun Hsu; Bing Hu; Dong Hu; Li-Fang Hu; Ming Chang Hu; Ronggui Hu; Wei Hu; Yu-Chen Hu; Zhuo-Wei Hu; Fang Hua; Jinlian Hua; Yingqi Hua; Chongmin Huan; Canhua Huang; Chuanshu Huang; Chuanxin Huang; Chunling Huang; Haishan Huang; Kun Huang; Michael L.H. Huang; Rui Huang; Shan Huang; Tianzhi Huang; Xing Huang; Yuxiang Jack Huang; Tobias B. Huber; Virginie Hubert
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field. © 2020 Informa UK Limited, trading as Taylor & Francis Group.
PolSAR calibration and reconstruction of hybrid polarimetric RISAT-1 data for pseudo quad-pol decomposition: A comparison with quad-pol
(SPIE, 2016) Shashi Kumar; Vivek Gupta; Pratyusha Gonnuru; Sushil Kumar Joshi
A new approach to reconstruction of pseudo quad-polarized data from hybrid polarimetric data has been presented in this research. The algorithm is based on certain assumptions which were validated upon testing the aptness of the results and their comparison with true optical images of the region under study. This involved direct construction of the 3X3 coherency matrix from the 2X1 scattering matrices obtained from the hybrid polarimetric data. The reasonableness of the assumptions were tested by decomposing the reconstructed pseudo quad-pol data using a coherent decomposition mechanism. The data set used in this project was Level-1 FRS-1 Hybrid Polarimetric data and FRS-2 Quad-pol data of RISAT-1. Reliable scattering retrieval from SAR data involves the calibration of the data. Polarimetric calibration was performed on real and imaginary channels of the single look complex SAR data. The newly developed algorithm was implemented on calibrated data. To extract complete information of different scattering elements of any location, second order derivative of scattering matrix is the most suitable and widely used matrix. Coherency matrix of pseudo quad-pol obtained from hybrid polarimetric data using reconstruction algorithm was decomposed using Yamaguchi four component decomposition for scattering information extraction. The obtained surface, double-bounce and volume scattering were compared with the scattering elements of hybrid-polarimetric decomposition, m-alpha and decomposition of quad-pol data of RISAT-1. The comparison revealed that the results obtained were satisfactory and thus the assumptions made during the reconstruction of pseudo quad-pol data were reasonable for specific purposes. Further comparisons of results using different decompositions technique at pixel level comparison can help better understand the aptness of the algorithm. COPYRIGHT © SPIE. Downloading of the abstract is permitted for personal use only.
Superior biomaterials using diamine modified graphene grafted polyurethane
(Elsevier Ltd, 2016) Dinesh K. Patel; Vivek Gupta; Ashish Dwivedi; Sanjeev K. Pandey; Vinod K. Aswal; Dipak Rana; Pralay Maiti
Surface modification of graphene oxide has been performed using diamine moieties with varying chain length and subsequently chemically grafted with long chain polyurethane for wrapping up of graphene sheet with large polymer chains. Functionalization of graphene and its subsequent grafting have been verified through spectroscopic measurements like NMR, FTIR and UV–visible spectroscopy and the uniform dispersion of graphene sheet in polyurethane matrix is achieved. Nanohybrids exhibit better thermal and mechanical responses along with greater self-assembly as compared to pure polymer. Nanometer dimension molecular sheet to gradual increased size of the order of tens of nanometer, hundreds of nanometer to micron scale assembly has been captured through XRD, small angle neutron scattering, AFM and optical microscopy, respectively. Nature of self-assembly associated with stronger interactions sustain the release of embedded drug (anticancerous dexamethasone) from nanohybrid and larger size of inhomogeinities for longer spacer length further sustain the drug release and thereby able to control the release rate of drug by articulating the chemistry of graphene modifications with suitable spacer length of diamine. Biocompatibility of the nanohybrids is verified with cell line studies using human breast cancer cells MDA-MB-231in terms of cell viability, cell adhesion, fluorescence image, reactive oxygen species and mitochondrial tracker measurements indicating better responses of nanohybrid vis-à-vis pure polyurethane. Thus, the control release of the dexamethasone drug from the nanohybrids along with better biological responses clearly suggests a novel biomaterial for the drug carrier. © 2016 Elsevier Ltd