Title:
Detection of Leptomonas sp. parasites in clinical isolates of Kala-azar patients from India

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dc.contributor.authorPankaj Srivastava
dc.contributor.authorVijay Kumar Prajapati
dc.contributor.authorManu Vanaerschot
dc.contributor.authorGert Van der Auwera
dc.contributor.authorJean Claude Dujardin
dc.contributor.authorShyam Sundar
dc.date.accessioned2026-02-07T04:58:29Z
dc.date.issued2010
dc.description.abstractWe report here nine unusual cases of Kala-azar, of which parasites were isolated and found by 18S rRNA gene sequencing to be most similar to Leptomonas species. One of these isolates was used to inoculate Balb/c mice; organs were collected and directly submitted to a genus-specific rDNA-ITS1 PCR analysis: this revealed the presence of both Leptomonas sp. and Leishmania donovani. Therefore, we conclude that there was a mixed infection of Leptomonas sp. and L. donovani in this isolate. We consider that mixed infection may be present in the patients themselves, Leptomonas persisting in them because of the immuno-suppression associated with Kala-azar. © 2010 Elsevier B.V.
dc.identifier.doi10.1016/j.meegid.2010.07.009
dc.identifier.issn15671348
dc.identifier.urihttps://doi.org/10.1016/j.meegid.2010.07.009
dc.identifier.urihttps://dl.bhu.ac.in/bhuir/handle/123456789/21488
dc.subjectHsp70 PCR-RFLP
dc.subjectKala-azar
dc.subjectLeishmania donovani
dc.subjectLeptomonas
dc.subjectRDNA-ITS1 PCR
dc.subjectVisceral leishmaniasis
dc.titleDetection of Leptomonas sp. parasites in clinical isolates of Kala-azar patients from India
dc.typePublication
dspace.entity.typeArticle

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