Copper catalysed C-N bond formation via a sequential acylation and deacylation process: A novel strategy for the synthesis of benzanilides

Abstract

An efficient and mild oxidative amidation of aldehydes by means of acetanilides as amine components has been developed for the first time using copper catalysis. The approach is versatile and proceeds through sequential acylation and deacylation steps to afford benzanilides. © The Royal Society of Chemistry 2015.