Metastatic testicular cancer in a patient with arsenical keratosis

Abstract

Arsenicosis is a multisystem disorder, with many cutaneous features. The cutaneous manifestations take the form of pigmentary changes, hyperkeratosis, and skin cancers (Bowen's disease, squamous cell carcinoma, and basal cell carcinoma). It is a known carcinogen and there is association between chronic arsenic exposure and malignancy of bladder, lung, liver, kidney and other visceral malignancies. Our patient came from an endemic area where levels of arsenic are high in drinking water and had features of arsenical keratosis for past fifteen years along with metastatic testicular cancer at the time of presentation. Arsenic exposure may increase the risk of testicular cancer.