Histochemical response of alkaline phosphatase activity during the healing of cutaneous wounds in a cat-fish

Abstract

The activity of alkaline phosphatase in the various tissue components of the regenerating skin of a cat-fish has been studied. A marked increase in alkaline phosphatase activity in the cells of migrating epithelium has been correlated with their highly active state. High alkaline phosphatase in the basal cells after 2 days has been found to have played an important role in cell multiplication and differention. The functional significance of this enzyme is discussed in relation to the granulation tissue formation. © 1983 Birkhäuser Verlag.