Evidence-Based Therapeutic Potential of Natural Seed Oil of Desert Date/Ingudi (Balanites aegyptiaca Linn. Delile) in Chronic Diabetic Wound

Abstract

This study is to clarify the things said in Ayurveda and Sanskrit literature with evidence in today's context that Balanites aegyptiaca oil (BAO) was used on humans and animals to heal wounds without any side effects. BAO was tested for its wound-healing potential on a diabetic patient. The topical application of the BAO caused wound closure that was ascertained by histopathological changes that occurred during the treatment at the site of application. The phytochemical analysis of BAO resulted in the isolation of potential marker compounds such as diosgenin, caffeic acid, stigmasterol, and fatty acids that may be contributing factors to its wound healing potential. However, underlying mechanisms need to be explored to understand the mechanism behind their wound-healing property. © 2023, The Author(s), under exclusive licence to The National Academy of Sciences, India.