Experimental study of disciplined regular diet on diseases of Purishvaha srotas in mice

Abstract

By considering the beneficial references concerning with disciplined diet which are mentioned in Ayurveda viz, in Charak Samhita, Sushruta Samhita, Yogaratnakara and Sharandhara Samhita and also about the laboratory approved diet for animals, three diets were formulated which are convenient for animals, which are as follows, Diet-1: Lab approved diet, content of 10 kg mixture which includes, Wheat flour: 6 kg, Maize flour: 3 kg, Fibre husk: 500 g, Sugar: 500 g, Salt: 100 g, Mineral powder (Agrimin forte, Galaxo, India.): 1000 g. Diet-2: Sarvarasahara (Disciplined regular diet mentioned in Ayurveda), which contains, Vilepi: It is a form of paste or homogeneous mixture of nutrient flours of Yava (malt), Shalishashtika (old rice), Tuvar dal (pigeon pea), Msoora (Lentil) spiced or zest with Ghrita, Saindhava (Rock salt), Jira (Cuminum cyminum), Ardraka (ginger) and garnished with fresh leaves of Dhanyaka (coriander), Rasayana: It is a sort of best tonic mentioned in Ayurveda i.e. the mixture of Ghrita and Godugdha (cow's milk) and Diet-3: Ekarasahara (continuous use of same diet). Histological changes were observed after 15 days of stoppage of medicine which are taken as causative factors for inducing the symptoms coated into Pureeshvaha Srotodushti lakshana, mainly constipation and diarrhoea. It was observed that Group- II and Group- III showed large ulcers some superficial as well deep reaching the muscular layer, infiltration of neutrophil was more in comparison to Group- IV and V, blunting of the villi as well as loss of villi compared than Group- IV and Group- V respectively. Thus, it can be suggested that maintenance of the disciplined diet as mentioned in "Charak Samhita" facilitates better healing to the intestinal mucosa injury induced both in constipation as well as in diarrhoea.