Generation and Regeneration of the C(sp3)-F Bond and 1,4-NADH/NADPH via Newly Designed S-gC3N4@Fe2O3/LC Photocatalysts under Solar Light

Abstract

Due to the pharmaceutical, biological, physical, and chemical properties of fluorinated compounds and 1,4-NADH/NADPH, these species have attracted a lot of attention from researchers across the chemical society. Despite their crucial significance, present methods of regenerating cofactors (1,4-NADH/NADPH) as well as inserting fluorine into organic compounds suffer from ruthless drawbacks. Herein, we designed a highly efficient S-gC3N4@Fe2O3/LC photocatalyst, and its in situ generations were accomplished by calcinations of Fe2O3, melamine (M), thiophenol (T), and lignin carbon (LC). The Fe2O3part performs similar to an additional light harvester, gifting utmost photo-generated electrons, whereas the carbon part bridges a "thoroughfare" to make easy electron transfer from Fe2O3to S-gC3N4(Schemes 1 and 2). Therefore, the newly designed S-gC3N4@Fe2O3/LC photocatalyst is more efficient for the generation and regeneration of the C(sp3)-F bond and 1,4-NADH/NADPH due to its surface active sites and defects. © 2022 American Chemical Society. All rights reserved.