An efficient multichannel probe to detect anions in different media and its real application in human blood plasma

Abstract

A simple coumarin derived chromo and fluorogenic chemosensor has been synthesized and tested to detect anions in different medium. The designed chemosensor has shown a high colorimetric response for F- and AcO- ions in acetonitrile in which the color of solution changed from a yellow-green to red and orange respectively whereas, in aqueous medium the probe showed high fluorogenic response and selectively reacted with cyanide through a Michael type nucleophilic addition reaction in which a nonfluorescent (switched-off) color of the solution, "turn-on" to became fluorescent blue (switched-on). The multichannel mode of interaction between the probe and anions has been confirmed by absorption, emission, FT-IR, NMR, ESI-MS spectral data analysis. Moreover, the probe has shown high sensitivity to detect cyanide in a real sample, human blood plasma as well as on paper strips. This journal is © the Partner Organisations 2014.