β-Oxodithioesters

Abstract

(A) Samuel et al.4 reported the synthesis of thiophenes by alkylation of β-oxodithioester with α-haloketones. Depending on the combination of base and solvent, differently substituted thiophenes are obtained. (Chemical Equation) (B) β-Oxodithioester in the presence of DMAP reacted with dialkyl acetylenedicarboxylate to give 2,3,4-trisubstituted thiophenes in high yield in short reaction times. (Chemical Equation) (C) Samuel et al.6 have reported the synthesis of 2-ylidene-1,3-oxathioles in good yield using β-oxodithioester and α-haloketone in the presence of NaH in toluene. (Chemical Equation) (D) Chromene and benzochromene-2-thiones were efficiently synthesized in high yield by the reaction of β-oxodithioester and 2-hydroxy benzaldehyde/naphthaldehyde under solvent-free conditions using SiO2·H2SO4 as the catalyst. (Chemical Equation) (A) Samuel et al.4 reported the synthesis of thiophenes by alkylation of β-oxodithioester with α-haloketones. Depending on the combination of base and solvent, differently substituted thiophenes are obtained. (Chemical Equation) (B) β-Oxodithioester in the presence of DMAP reacted with dialkyl acetylenedicarboxylate to give 2,3,4-trisubstituted thiophenes in high yield in short reaction times. (Chemical Equation) (C) Samuel et al.6 have reported the synthesis of 2-ylidene-1,3-oxathioles in good yield using β-oxodithioester and α-haloketone in the presence of NaH in toluene. (Chemical Equation) (D) Chromene and benzochromene-2-thiones were efficiently synthesized in high yield by the reaction of β-oxodithioester and 2-hydroxy benzaldehyde/naphthaldehyde under solvent-free conditions using SiO 2·H2SO4 as the catalyst. (Chemical Equation). © Georg Thieme Verlag Stuttgart · New York.