Diagnostic Approaches for Covid-19: Present Status and Future Prospects

Abstract

During this COVID-19 outbreak, diagnostic tests were crucial in controlling its spread. This pandemic, which was caused by the SARS-CoV-2 virus, has created an urgent need for rapid diagnostic testing to enable efficient treatment and control of COVID-19. Many institutes and companies are trying to develop effective methods for detecting COVID-19. The essential indicative instrument presently utilized is reverse transcription-polymerase chain response (RT-PCR), which can have great affectability. Tragically, execution costs, time is taken, and false-negative results have limited the use of RT-PCR. Lateral flow assays (LFAs) are a type of diagnostic test that is clinically sensitive enough, might bridge various inadequacies in the present RT-PCR system, especially in low-and middle-income countries. In basic hospitals and laboratories, AuNP-LFA is a viable technique for diagnosing COVID-19, especially in emergency settings where a large number of samples must be examined quickly. This review summarizes the different diagnostic approaches for detecting the SARS-COV-2. This review thus provides guidelines for the scientists and technicians engaged in detecting SARS-COV-2. An accurate and sensitive detection system would enormously benefit in controlling this pandemic. © 2022 by the authors.