Synthesis of functionalized alkenes via Cu(i)-catalysed allylation of acetanilides using Morita-Baylis-Hillman bromides

Abstract

An easy access to functionalized alkenes has been developed by the C-H functionalization of anilides with Morita-Baylis-Hillman (MBH) bromides in the presence of copper chloride, TBHP and acetic acid. Unsubstituted as well as ortho/meta-substituted anilides exclusively give rise to the para-allylated products, whereas para-substitution brings about the formation of ortho-allylated anilides. © 2023 The Royal Society of Chemistry.