Fungal Rhinosinusitis Caused by Uncommon Scedosporium Apiospermum Fungus species: A Case Report and Review of Literature

Abstract

We report a case of rhinosinusitis caused by Scedosporium apiospermum in a 35-year-old male who presented with nasal discharge. Diagnosis was made by demonstration of hyaline hyphae in the tissue biopsy and culture characteristics. The patient was managed by surgical debridement and oral voriconazole. The patient responded well to the treatment. This case signifies the importance of culture isolation and antifungal minimal inhibitory concentration (MIC) in each case of fungal rhinosinusitis. © Association of Otolaryngologists of India 2025.