Transition metal complexes of 5-chlorouracil

Abstract

Complexes of 5-chlorouracil (5-ClU) (1) with 3d metal ions were characterized by elemental analysis, various spectroscopic methods (i.r., u.v. spectroscopy) and magnetic susceptibility measurements. The spectral evidence suggest that 5-ClU behaves as bidentate ligand in NiII, CuII, ZnII, and CdII compounds, coordinating through its one carbonyl oxygen and one nitrogen whereas with MnII and CoII it coordinates through the carbonyl oxygen only. The insolubility of the new complexes in organic solvents suggests that these are polymeric except for the CoII complex which is soluble in pyridine. There is probable OH bridging in the MnII and CuII complexes and the 5-ClU may bridge in the rest. © 1988 Chapman and Hall Ltd.