Effect of Asparagus recemosus on the mammary gland and genital organs in virgin rat

Abstract

Asparagus racemosus (A.R.) root extract administered orally with the dose of 30 mg/100 gm body weight daily for 20 days, to the virgin adult female albino rats. On gross examination the effect of the drug showed mammary gland getting prominent, vaginal opening dilated and more numerous blood vessels around the genital organs. The whole uterii of the treated group were found significantly heavier (p<0.001). Microscopic examination of the treated group revealed the hyperplasia of glandular tissue of the mammary gland. The various layers of the wall of vagina and uterus revealed thickening and dilated blood vessels. Compact cornification of the vaginal epithelium and other findings, in treated group of animal, indicating the estrogenic effect of the drug. The findings suggest dose related phytoesterogenic action of A.R. root extract. Therapeutic use of A.R., in human as feminine tonic to promote the development of secondary sex characters in young female.