Title:
Arbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties

dc.contributor.authorVaibhav Mishra
dc.contributor.authorAstha Shukla
dc.contributor.authorSukanya Pandeti
dc.contributor.authorManoj Kumar Barthwal
dc.contributor.authorHaushila Prasad Pandey
dc.contributor.authorGautam Palit
dc.contributor.authorTadigoppula Narender
dc.date.accessioned2026-02-07T05:40:29Z
dc.date.issued2013
dc.description.abstractNyctanthes arbortristis Linn (Oleaceae) is widely distributed in sub-Himalayan regions and southwards to Godavari, India commonly known as Harsingar and Night Jasmine. In continuation of our drug discovery program on Indian medicinal plants, we isolated arbortristoside-A (AT) and 7-O-trans-cinnamoyl-6β-hydroxyloganin (6-HL) from the seeds of N. arbortristis. AT and 6-HL exhibited anti ulcer activity in experimentally induced ulcer models including cold restraint stress (CRU), alcohol (AL), pylorus ligation-induced gastric ulcer (PL) models and they also showed ulcer healing effect in chronic acetic acid-induced ulcer model (AC). © 2013 Elsevier GmbH. All rights reserved.
dc.identifier.doi10.1016/j.phymed.2013.04.010
dc.identifier.issn1618095X
dc.identifier.urihttps://doi.org/10.1016/j.phymed.2013.04.010
dc.identifier.urihttps://dl.bhu.ac.in/bhuir/handle/123456789/24900
dc.subjectArbortristoside-A 7-O-Trans-cinnamoyl6β- hydroxyloganin
dc.subjectGastric ulcer
dc.subjectNyctanthes arbortristis
dc.subjectPGE2
dc.subjectProton pump
dc.titleArbortristoside-A and 7-O-trans-cinnamoyl-6β-hydroxyloganin isolated from Nyctanthes arbortristis possess anti-ulcerogenic and ulcer-healing properties
dc.typePublication
dspace.entity.typeArticle

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