Title:
Human ENPP1 gene polymorphism in DKD patients: a hospital-based case control study

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dc.contributor.authorS. Chandra
dc.contributor.authorA.K. Singh
dc.contributor.authorM. Singh
dc.contributor.authorP. Pandey
dc.contributor.authorC.S. Azad
dc.contributor.authorS. Singh
dc.contributor.authorP. Das
dc.contributor.authorR.G. Singh
dc.date.accessioned2026-02-07T10:49:19Z
dc.date.issued2021
dc.description.abstractAim: The aim of present study was to investigate the association of the ENPP1 (K121Q) gene polymorphism with DKD in eastern Uttar Pradesh population. Methods: A total of 162 DKD and 155 apparently healthy controls were enrolled and K121Q polymorphism was determined by PCR-RFLP followed by sequencing. Results: It was observed that genotype KQ was more frequent in patients than controls and allelic frequencies of Q allele were higher in DKD (Q 21.3%) than control (Q 15.81%). It depicted that Q allele may be associated with DKD patient and has more risk in eastern UP population. Conclusion: The study indicated a significant association of KQ polymorphism of the ENPP1 gene with DKD in the eastern Uttar Pradesh population. © 2020, Research Society for Study of Diabetes in India.
dc.identifier.doi10.1007/s13410-020-00841-4
dc.identifier.issn9733930
dc.identifier.urihttps://doi.org/10.1007/s13410-020-00841-4
dc.identifier.urihttps://dl.bhu.ac.in/bhuir/handle/123456789/39018
dc.publisherSpringer
dc.subjectChronic kidney disease
dc.subjectDiabetic kidney disease
dc.subjectDKD
dc.subjectENPP1
dc.subjectNephropathy
dc.subjectPolymorphism
dc.titleHuman ENPP1 gene polymorphism in DKD patients: a hospital-based case control study
dc.typePublication
dspace.entity.typeArticle

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