Complexes Of Zn(II), Cu(II), Ni(II) And Co(II) Tetrathiocyanato Mercurates(II) With Hydrazides And Their Biological Activity

Abstract

A new series of bimetallic tetrathiocyanate complexes of the type MM’(SCN)4.L, M = Zn(II), Cu(II), Ni(II), Co(II), M’ = Hg and L = benzoylhydrazide (BH), oxaldihydrazide (ODH) and malondihydrazide (MDH) have been synthesized in dilute ethanolic medium. The 1:1 metal:ligand complexes, which have been characterized by elemental analysis, magnetic moment data, electronic and infrared spectra, are insoluble in water as well as common organic solvents and decompose above 250°C without melting. The ligands act as bidentate coordinating species in the complexes. Some of these bimetallic complexes have been tested against Escherichia coli and Klebsillea pneumoniae bacteria and Aspergillusflavus, Penicillium sp. fungi, and were found to be biologically active. © 1985, Taylor & Francis Group, LLC. All rights reserved.