Title: Multicomponent Synthesis of S-Benzyl Dithiocarbamates from para-Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer’s Disease
| dc.contributor.author | Rapelly Venkatesh | |
| dc.contributor.author | Gauri Shankar | |
| dc.contributor.author | Aswathi C. Narayanan | |
| dc.contributor.author | Gyan Modi | |
| dc.contributor.author | Shahulhameed Sabiah | |
| dc.contributor.author | Jeyakumar Kandasamy | |
| dc.date.accessioned | 2026-02-07T11:01:38Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Multicomponent synthesis of biologically relevant S-benzyl dithiocarbamates from para-quinone methides, amines, and carbon disulfide are described under catalyst and additive-free conditions. The reactions proceeded at room temperature in a short span of time with excellent yields. One of the synthesized compounds, 3e showed considerable acetylcholinesterase (AChE) inhibitory (51.70 + 5.63% at 20 μm) and antioxidant (63.52 ± 1.15 at 20 μm) activities. © 2022 American Chemical Society. | |
| dc.identifier.doi | 10.1021/acs.joc.2c00423 | |
| dc.identifier.issn | 223263 | |
| dc.identifier.uri | https://doi.org/10.1021/acs.joc.2c00423 | |
| dc.identifier.uri | https://dl.bhu.ac.in/bhuir/handle/123456789/41325 | |
| dc.publisher | American Chemical Society | |
| dc.title | Multicomponent Synthesis of S-Benzyl Dithiocarbamates from para-Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer’s Disease | |
| dc.type | Publication | |
| dspace.entity.type | Article |