Existing pharmacological challenges and the need for improved therapies

Abstract

Effective diabetes management is crucial for preventing both acute and long-term complications, improving quality of life, and reducing the economic burden associated with the disease. For this purpose, targeting specific enzymes involved in glucose metabolism could be a useful therapeutic technique. Enzyme inhibitors, enzyme replacement treatment, and gene therapy are among the topics being researched. Regular monitoring, medication adherence, a healthy lifestyle, and ongoing medical care are critical components of effective diabetes management. It is important for individuals with diabetes to work closely with their healthcare team to develop and implement a personalized management plan. © 2025 Elsevier Inc. All rights reserved.