Commentary: A treatise on neurodegenerative disorders and protection by structurally diverse antioxidants and functional foods

Abstract

The etiology of neurodegenerative disorders and its consequences has been demonstrated due to continuous and progressive loss of brain cells, preceding to the dysfunctions and degeneration of the neuronal functions and nervous system. In global scenario, World Health Organization reports that diverse neurological disorders and brain injuries, including Parkinson's disease, Alzheimer's disease, epilepsy, neuronal infections, multiple sclerosis, and stroke, affect about one billion people worldwide. The proceeding of advancing age-induced neurodegeneration is a progressive deterioration of neuronal cells, its structural integrity, and functions, which eventually steer to cognitive disability and dysfunctions, and dementia. Generally, neurodegenerative disorders and dysfunctions strike primarily in the middle and advancing age populations, and this prevalence is growing up remarkably in aged population. Selected structurally diverse antioxidants, standardized botanical extracts, and nutraceuticals enriched in phytonutrients and antioxidants have been extensively demonstrated to inhibit these critical inflammatory elements and rectify the vital oxidant/antioxidant imbalance in humans suffering from diverse neurodegenerative disorders. © 2021 Taylor & Francis Group, LLC. All rights reserved.