Title:
Dendritic cell therapy in advanced gastric cancer: A promising new hope?

dc.contributor.authorMallika Tewari
dc.contributor.authorShipra Sahai
dc.contributor.authorRaghvendra R. Mishra
dc.contributor.authorSunit K. Shukla
dc.contributor.authorHari S. Shukla
dc.date.accessioned2026-02-07T05:33:12Z
dc.date.issued2012
dc.description.abstractAdvanced gastric cancer carries a very poor prognosis when the tumor becomes unresectable. Even with the best currently available chemotherapy regimens the survival rate remains dismal. A recent breakthrough in the treatment paradigm has been the approval of trastuzumab, a monoclonal antibody, in HER2-positive metastatic gastric cancer. A large number of trials are underway using dendritic cells (DCs) in a number of human malignancies and do show a ray of hope in management of these patients. This review attempts to summarize tumor immunology and the current data regarding use of DCs in gastric cancer therapy. © 2012 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.suronc.2012.03.003
dc.identifier.issn18793320
dc.identifier.urihttps://doi.org/10.1016/j.suronc.2012.03.003
dc.identifier.urihttps://dl.bhu.ac.in/bhuir/handle/123456789/23675
dc.subjectCancer vaccine
dc.subjectDendritic cell
dc.subjectGastric cancer
dc.subjectImmune escape
dc.titleDendritic cell therapy in advanced gastric cancer: A promising new hope?
dc.typePublication
dspace.entity.typeReview

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