Browsing by Author "Satish Chand"

Now showing 1 - 3 of 3
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    Ashy dermatosis-like pigmentation due to ethambutol
    (Medknow Publications and Media Pvt. Ltd, 2008) Neeraj Srivastava; Lakhan Solanki; Satish Chand; Rajendra Garbyal; Sanjay Singh
    [No abstract available]
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    Bizarre, polycyclic, circinate, and floral-patterned reversible depigmentation in a patient with chronic bullous disease of childhood
    (2008) Lakhan Singh Solanki; Neeraj Srivastava; Satish Chand; Sanjay Singh
    [No abstract available]
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    Pseudoxanthomatous mastocytosis
    (2008) Neeraj Srivastava; Satish Chand; Sanjay Singh
    A 50-year-old woman presented with itchy, multiple, flat, yellowish, waxy papules and plaques diffusely involving her face, trunk, and upper extremities for 5 years (Fig. 1). Itching was moderate to severe in intensity and was episodic, without any identifiable aggravating or relieving factors. On rubbing the lesions with a blunt object erythema was elicited. Her ophthalmological examination was normal. Her complete hemogram was normal along with other routine investigations. Patient's slit skin smear for acid-fast bacilli and rk39 dip-stick ELISA for post-kala-azar dermal leishmaniasis were negative. Ultrasound examination of her abdomen was normal and skeletal survey showed no evidence of bony changes. Histological examination showed diffuse dense infiltrate of numerous mast cells filling up the papillary dermis and most of upper- and mid-reticular dermis. Overlying epidermis showed moderate epidermal hyperplasia and hyperpigmentation. There was sparse scattering of neutrophils within the infiltrate. Extracellular mast cells granules were also seen (Fig. 2). Diagnosis of diffuse cutaneous mastocytosis of pseudoxanthomatous variety was made. The patient was prescribed treatment in the form of H1 and H2 blockers (fexofenadine and ranitidine) and trimethylpsoralen and ultraviolet A (PUVA) photochemotherapy. After 2 months of treatment, there has been marked improvement in the appearance and itching. © 2008 The International Society of Dermatology.