Chaubey T.N.Borpatra P.J.Pandey S.K.2025-01-132025-01-13202414770520https://dl.bhu.ac.in/ir/handle/123456789/1182A novel method for synthesizing 2-acyl benzothiazoles and benzoxazole derivatives has been developed via the annulative coupling of sulfoxonium ylides with 2-aminobenzenethiol and 2-aminophenol derivatives, respectively. This metal-free, one-pot protocol employs elemental sulfur as a mediator to efficiently construct C-N, C-S, or C-O bonds and demonstrates a broad range of functional group compatibility. The potential utility of this approach is further demonstrated through large-scale reactions and the synthesis of some bioactive compounds. � 2024 The Royal Society of Chemistry.enArticle10.1039/d4ob01256a