Gola, Ajay KantSharma, AjayPandey, Satyendra Kumar2025-01-282025-01-28202315237060https://dl.bhu.ac.in/ir/handle/123456789/22763An efficient catalyst- and additive-free facile synthesis of ?-carbonyl-??-amide sulfoxonium ylides from isocyanates and ?-ketosulfoxonium ylides with complete atom economy has been described. The ?-ketosulfoxonium ylides and isocyanates adorned with various functional groups were well-tolerated and afforded moderate to high yields of the ?-carbonyl-??-amide sulfoxonium ylide derivatives. Finally, using large-scale reactions and converting the synthesized ylides into other valuable compounds, we demonstrated the practicality of this synthetic method. � 2023 American Chemical Society.enArticlehttps://doi.org/10.1021/acs.orglett.3c00239