Yadav M.S.Jaiswal M.K.Kumar S.Singh S.K.Garai S.Tiwari V.K.2025-01-132025-01-13202418614728https://dl.bhu.ac.in/ir/handle/123456789/2695The documented work highlighted the synthesis of bis(benzotriazol-1-yl) methane derivatives using silicomolybdic acid (SMA) and successfully implemented in the stereoselective synthesis of diverse pyrrolo[3,4-b]pyridin-5-one and pyridyl isoindolinones derivatives in one-pot. The pyridinamide precursor with diverse alkynes furnished Z-selectivity of pyrrolo[3,4-b]pyridin-5-one across exocyclic C=C bond while the various benzamides on treating with 2-ethynyl pyridine afforded (E)-pyridylisoindoline-1-ones as a major isomer. The single-crystal X-ray diffraction provides strong evidence in favor of the existence and orientation of developed compounds. The broad substrate scope, easy accessibility of substrates, high stereoselectivity, scale-up synthesis, and crystal evidence demonstrate the merits of the current decorum. � 2024 Wiley-VCH GmbH.enBenzotriazoleBis(benzotriazol-1-yl) ligandCyclizationDomino synthesisFused heterocycleSilicomolybdic acidStereoselectivityArticle10.1002/asia.202401301