Browsing by Author "Hanjabam Barun Sharma"

Now showing 1 - 20 of 20

An Assessment of Smartphone Use on Brainstem Auditory Evoked Potentials in Healthy Young Adults in North India Short Title: Assessing BAEP Changes in Young Smartphone Users
(SAGE Publications Inc., 2025) Ayushi Seth; Samir Kumar Singh; Anita Gupta; Hanjabam Barun Sharma
Background: A smartphone is an essential part of our daily existence. Smartphones are used by about 5.26 billion people. Purpose: The purpose of this study was to determine how the duration of smartphone use influenced brainstem auditory evoked potentials (BAEPs). Methods: BAEPs were measured using BERAGRAPH in 41 young healthy persons in an observational cross-sectional study. Results: When daily smartphone calling time is 60 minutes, there is a statistically insignificant difference in smartphone usage length (5 years and >5 years) between the two groups among BAEPs. Conclusion: Despite the P-value being insignificant, there is a positive relationship between smartphone use in years and absolute wave latencies and interpeak latencies of brainstem evoked potentials. © The Author(s) 2025.
Anthropometric and physiological basis of endurance capacity in young indian field hockey players
(Association of Physiologists and Pharmacologists of India, 2017) Hanjabam Barun Sharma; Jyotsna Kailashiya
High endurance capacity, expressed by VO2max, is essential for optimal performance and is influenced by anthropometric and physiological parameters. 30 Indian young national level field-hockey players were studied to evaluate their endurance capacity and associated parameters. VO2max, relative physical work capacity at 170 bpm (rPWC), heart rate recovery (HRR3/6 at 3rd/6th minute), hemoglobin concentration (Hb), resting heart rate (rHR) and blood pressure (rBP), maximum heart rate (HRmax), basal metabolic rate (BMR), demographic and anthropometric parameters were measured and analyzed. After controlling the effect of gender by partial correlation, VO2max correlated significantly and positively with age, BMR, HRmax, HRRs, rPWC and Hb; and negatively with body weight, body fat%, BMI (body mass index), rHR and rBP. Body fat% had the maximum negative effect on endurance capacity. HRR3, rHR and rPWC together contributed a statistically significant 95.2% of the total variance in VO2max. Various linear regression equations were generated for assessing endurance capacity. © 2017, Association of Physiologists and Pharmacologists of India. All rights reserved.
Assessment of obesity indices for prediction of hyperglycemia in adult population of Varanasi (Uttar Pradesh), India
(Association of Physiologists and Pharmacologists of India, 2020) Neha Rai; Hanjabam Barun Sharma; Renu Kumari; Jyotsna Kailashiya
Objectives: Obesity is a known risk factor for diabetes mellitus. Multiple obesity indices are available to assess and classify obesity status, including Body Mass Index (BMI), Waist Circumference (WC), and Waist-Height Ratio (WHtR). The present research was conducted to assess these obesity indices for their usefulness in predicting hyperglycemia. Materials and Methods: BMI, WC, WHtR, and Random Capillary Blood Glucose (RCBG) levels were measured in total 188 adult volunteers from Varanasi, Uttar Pradesh, India. Pearson correlation, unpaired Student’s t-test, and Chi-square tests were applied to assess associations and difference of measured parameters among different categories. Receiver operating curve analysis was performed to find best obesity indices to predict hyperglycemia (RCBG ≥140 mg/dl) and to find optimal cut off values for prediction. Results: Age of subjects, WC and WHtR (but not BMI) were found significantly correlated with RCBG levels. WHtR classified highest number of subjects as obese, compared to BMI and WC. WHtR was also found to be the best obesity index to predict hyperglycemia in both male and female subjects. Conclusion: WHtR can be used as cost effective, non-invasive, and convenient obesity index for screening and prediction of hyperglycemia in apparently healthy adult subjects. Thus, identified subjects can further be advised to undergo blood glucose testing for the early detection of diabetes and prediabetes. © 2020 Published by Scientific Scholar on behalf of Indian Journal of Physiology and Pharmacology.
Characteristics of Auditory Brainstem Response in Night-shift Health Workers
(SAGE Publications Inc., 2025) Samir Kumar Singh; Poonam Jyoti Rana; Anita Gupta; Dibyodyuti Samaddar; Hanjabam Barun Sharma
BackgroundWith technological advancement and economic competitiveness there is an exponential rise in the number of shift workers. Worldwide, healthcare workers constitute the single largest proportion of workers who work on shift duty in order to provide round-the-clock healthcare services to patients. Various studies have demonstrated an association between circadian cycle disturbance due to shift work and adverse health impacts.PurposeThe purpose of the study was to investigate the impact of night shift work on the brainstem-evoked auditory potentials in nursing interns who had been assigned to their first night shift after working day shifts.MethodsA longitudinal, self-case-control study was designed with a sample of 67 nursing interns. Brainstem evoked response audiometry (BERA) had been done after completion of their first posting in Day-shift and then after completion of Night-shift. The paired t-test was used for data analysis.ResultsThe findings of the study showed significant changes in latencies of wave II (p < .0001), wave IV (p < .0001), wave V (p = .012 & .30), interpeak latency III-V (p = .009 & .003) and V/I ratio (p < .0001) for both ears.ConclusionsBERA is an objective non-invasive test to evaluate hearing ability by measuring increased latency and interaural latency difference. After night shift, there were significant changes in auditory acuity which was highly suggestive of delayed transmission in auditory pathway. Hearing impairment has a cascading effect on cognition which may affect night-shift workers’ daily activities and may lead to medical error and risk to patient safety. © The Author(s) 2024. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Characteristics of Auditory Brainstem Response in Night-shift Health Workers
(SAGE Publications Inc., 2024) Samir Kumar Singh; Poonam Jyoti Rana; Anita Gupta; Dibyodyuti Samaddar; Hanjabam Barun Sharma
Background: With technological advancement and economic competitiveness there is an exponential rise in the number of shift workers. Worldwide, healthcare workers constitute the single largest proportion of workers who work on shift duty in order to provide round-the-clock healthcare services to patients. Various studies have demonstrated an association between circadian cycle disturbance due to shift work and adverse health impacts. Purpose: The purpose of the study was to investigate the impact of night shift work on the brainstem-evoked auditory potentials in nursing interns who had been assigned to their first night shift after working day shifts. Methods: A longitudinal, self-case-control study was designed with a sample of 67 nursing interns. Brainstem evoked response audiometry (BERA) had been done after completion of their first posting in Day-shift and then after completion of Night-shift. The paired t-test was used for data analysis. Results: The findings of the study showed significant changes in latencies of wave II (p <.0001), wave IV (p <.0001), wave V (p =.012 &.30), interpeak latency III-V (p =.009 &.003) and V/I ratio (p <.0001) for both ears. Conclusions: BERA is an objective non-invasive test to evaluate hearing ability by measuring increased latency and interaural latency difference. After night shift, there were significant changes in auditory acuity which was highly suggestive of delayed transmission in auditory pathway. Hearing impairment has a cascading effect on cognition which may affect night-shift workers’ daily activities and may lead to medical error and risk to patient safety. © The Author(s) 2024.
Comparison of Propofol and Ketofol on Transcranial Motor Evoked Potentials in Patients Undergoing Thoracolumbar Spine Surgery
(Korean Society of Spine Surgery, 2022) Ankur Khandelwal; Arvind Chaturvedi; Navdeep Sokhal; Akanksha Singh; Hanjabam Barun Sharma
Study Design: This was a double-blind randomized study. Purpose: The primary purpose was to compare the effects of propofol and ketofol on amplitudes and latencies of transcranial motor evoked potentials (TcMEPs) during thoracolumbar spine surgery. In addition, intraoperative hemodynamics and muscle power were compared. Overview of Literature: Propofol is commonly used during intraoperative TcMEP monitoring. However, propofol inhibits TcMEP amplitudes and causes hypotension in a dose-dependent fashion. Methods: Amplitude and latency of TcMEPs were recorded bilaterally from the abductor pollicis brevis (APB) and abductor hallucis (AH) muscles in 38 adult American Society of Anesthesiologists I and II patients undergoing thoracolumbar spine surgery. Baseline recordings of TcMEPs in both groups were recorded under propofol infusion. Group X patients then received propofol and fentanyl (1 mcg/ kg/hr), and group Y patients received ketofol and fentanyl (1 mcg/kg/hr). Bispectral index was maintained at 40–60 in both groups. Amplitude and latency were recorded at 30 minutes intervals for 2 hours. Results: Propofol caused no significant changes in amplitude and latency in any muscle. In contrast, amplitude increased significantly at all time points in the bilateral APB muscles and 60, 90, and 120 minutes in the left AH muscle without changes in latency in response to ketofol. When the two groups were compared, ketofol induced significantly higher amplitudes at 60, 90, and 120 minutes in the (left) APB, at all time points in the (right) APB, and at 120 minutes in both AH muscles, compared with propofol. Blood pressures were lower and fluid and vasopressor requirements were higher in group X. Muscle power was similar between the two groups. Conclusions: Ketofol facilitates TcMEP amplitudes without affecting latency. Use of ketofol resulted in a better and more stable hemodynamic profile than did use of propofol © 2022 by Korean Society of Spine Surgery This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
COVID-19 and CoVesity: Facing the challenge with lifestyle, exercise, and sports
(Taylor and Francis Ltd, 2024) Hanjabam Barun Sharma
[No abstract available]
Effect of oscillatory lower body negative pressure and isometric handgrip exercise on cardioautonomic tone of healthy individuals
(Scientific Scholar, 2024) Gagan Kumar Banodhe; Hanjabam Barun Sharma; Kishore K. Deepak
Objectives: The influence of the autonomic nervous system on the heart can be quantified by assessing changes in the heart rate variability (HRV) during orthostatic challenge and exercise. However, the combination of oscillatory lower body negative pressure (oLBNP) and isometric handgrip exercise (IHE) on HRV has not been previously investigated. Therefore, the present study aimed to assess the effects of (oLBNP) at sympathetic (0.1 Hz) and parasympathetic (0.25 Hz) frequencies and IHE at 30% of maximum voluntary contraction (MVC) on HRV in normal healthy individuals. Materials and Methods: We conducted a cross-sectional study on 18 healthy male subjects. Beat-to-beat blood pressure, lead-II electrocardiogram, and oLBNP chamber pressure were recorded continuously during oLBNP at 0.1 and 0.25 Hz for 3 min each and IHE at 30% of MVC (for 4 min) along with oLBNP at 0.1 or 0.25 Hz (oLBNP was added in last 3 min) each followed by HRV analysis. Results: The oLBNP at 0.25 Hz reduced the root mean square of successive inter-beat (RR) interval differences significantly as compared to baseline values and came to normal during the recovery phase (P = 0.008). The absolute power of the high-frequency band (HF power), Poincaré plot standard deviation perpendicular to the line of identity (SD1), and percentage of successive RR intervals that differ by more than 50 ms (pNN50) were also reduced significantly during oLBNP at 0.25 Hz and when IHE at 30% of MVC (IHE) was added to oLBNP at 0.25 Hz as compared to baseline (P < 0.05). Conclusion: oLBNP and IHE could be used as a non-invasive haemodynamic stressor to assess the neurocardiac axis and its mechanism of action during orthostatic stresses. © 2024 Published by Scientific Scholar on behalf of Indian Journal of Physiology and Pharmacology.
Expert Opinion on Management Advancements in Sarcopenia: From Muscle Wasting to Recovery
(Journal of Association of Physicians of India, 2025) Sanjay Kalra; Ashok Kumar Das; Narendra K. Kotwal; Lakshmi Nagendra; Rashi Agrawal; H. K. Ganesh; Sambit Das; Arun Kumar Chandresh Singh; Nitin K. Kapoor; Atul Dhingra; Abhilasha Jain; Sourabh C. Sharma; Vinod Gupta; Suneet Kumar Verma; Hanjabam Barun Sharma; Ram Prabhoo; Naresh Shetty; Sameer Muchhala; Nimitha Pinto
Sarcopenia, an age-related condition marked by the decline of skeletal muscle mass, strength, and function, often leads to loss of function, disability, and diminished quality of life (QoL) in the elderly population. Despite its growing prevalence, sarcopenia is frequently underdiagnosed and inadequately managed. Timely detection and appropriate interventions are crucial to slowing disease progression and minimizing associated risks. As standardized guidelines and individualized management plans are necessary to improve clinical outcomes, this consensus paper presents expert insights into advancements in sarcopenia management, including diagnostic criteria and therapeutic interventions, and the need for personalized screening tools for Indian demographics. Furthermore, experts emphasized the importance of a multimodal approach, integrating resistance exercise, nutritional optimization, and emerging pharmacological therapies for effective sarcopenia treatment. The role of anabolic agents such as nandrolone decanoate in muscle preservation is explored, alongside considerations for patient selection and safety. This paper underscores the importance of a patient-centered approach, which addresses both functional recovery and overall well-being of individuals at risk or diagnosed with sarcopenia. © The Author(s). 2025.
Gender difference in aerobic capacity and the contribution by body composition and haemoglobin concentration: A study in young Indian National hockey players
(Journal of Clinical and Diagnostic Research, 2016) Hanjabam Barun Sharma; Jyotsna Kailashiya
Introduction: Although gender difference in aerobic capacity is known, the contributing factors have been researched seldom. Aim: To investigate this gender gap and the contribution by percentage Body Fat (BF), Body Mass Index (BMI) and haemoglobin concentration (Hb). Materials and Methods: The study was conducted on 30 (17 males, 13 females) training status matched young hockey players. Healthy players who were playing upto national level competition were the inclusion criteria. BW (Body Weight), BF, BMI, LBM (Lean Body Mass), rHR (restring Heart Rate), HRR (Heart Rate Recovery), (Hb), a/rVO2max (absolute/relative), a/rPWC (Physical Work Capacity) and RMR (Resting Metabolic Rate) were measured and analysed. Results: There was significant gender difference in the measured parameters. Difference in a/rVO2max remained significant even after controlling for BF, BMI and Hb. Multiple regression and correlation analysis revealed gender difference in VO2max/LBM was due to: BMI(31.91%)>BF(27.60%)>(Hb)(9.91%). BMI also significantly contributed 3.66% of VO2max/LBM variance, independent of that by gender. Difference in RMR was mainly related to LBM, BF and BMI. Conclusion: The study provided an understanding for gender gap in aerobic capacity. Differences in BMI & BF were one of the main reasons. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.
Gender Variations in Brainstem Auditory Evoked Potentials in Emerging Adults of Northern India
(SAGE Publications Inc., 2025) Anita Gupta; Samir Kumar Singh; Jai Singh Yadav; Anandita Chakravartty; Hanjabam Barun Sharma
Background: Brainstem auditory evoked potentials (BAEPs) aid in the diagnosis of probable neurologic disorders of the VIIIth cranial nerve, the associated auditory pathways, and an estimation of hearing sensitivity, for those who are unable to reliably provide information through behavioural hearing evaluations. BAEPs exhibit variabilities due to numerous pathologic and non-pathologic factors. One of the factors that may have a significant impact on typical BAEPs is gender. Although there are numerous studies documenting gender as an influencing factor on auditory evoked potentials in older subjects, there are few comparable studies among subjects who are just entering adulthood. Objective: The current study aimed to understand the pattern of gender-based differences in BAEPs among emerging adults of Northern India. Methods: The present study was conducted on 120 normal subjects (70 females, 50 males) who were relatives (second degree) of the patients belonging to Northern India aged between 19 and 25 years old, at the Institute of Medical Sciences. Absolute latencies I, III, V and Inter-peak latencies I–III, I–V, III–V were measured separately for both ears. Statistical analysis was done by using the independent t-test and Mann-Whitney U test based on normality through SPSS version 20.0. Results: Results revealed a statistically significant difference in absolute latency of Wave I and inter-peak latency (IPL) of I–III, I–V in the right ear and in the left ear. Wave III and IPL III–V were found to be significant. Females showed shorter absolute latencies and IPLs as compared to males. Conclusion: Significant alterations in BAEPs provide evidence for the potential contribution of gender as an influencing factor in emerging adulthood. © The Author(s) 2025. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
How Much Time to Spend in Physical Activity, Sleep and be Sedentary in 24 h to Achieve Good Health?
(Springer, 2022) Tripat Deep Singh; Hanjabam Barun Sharma
One should have adequate amount of good quality sleep on a regular and consistent basis on weekdays and weekends along with adequate amount of physical activity and good nutrition for good health. We discuss current evidence in relation to sleep and physical activity and share how the general public can plan their 24 h incorporating adequate amount of good quality sleep and physical activity to achieve good health. We recommend 150 min of moderate to vigorous physical activity, 7–9 h of sleep and less than 8 h of sedentary time for adults. © 2022, The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd.
Impact of american heart association’s new hypertension guidelines (2017) on disease burden and association with obesity indices
(Association of Physiologists and Pharmacologists of India, 2020) Renu Kumari; Neha Rai; Hanjabam Barun Sharma; Jyotsna Kailashiya
Background: Hypertension (HTN) and obesity both are on rise in India as well as other countries. With introduction of new guidelines for HTN by American Heart Association (AHA) in 2017, the burden of disease is expected to be much higher than before. Aim of this study was to assess the impact of new AHA (2017) guidelines of hypertension classification on disease burden and its association with obesity. Materials and Methods: This cross sectional analytical study was conducted in total 210 subjects from Varanasi, India. Blood pressure and obesity indices (waist circumference, body mass index and waist-height ratio) were measured and analysed. Number of subjects having HTN according to American Heart Association’s (AHA) new (2017) and old [Seventh Report of the Joint National Committee (JNC) on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, 2003] guidelines were compared and association with obesity was estimated. Results: Total 149 (70.9%) subjects showed HTN according to new (AHA 2017) guidelines, compared to 81 (38.5%) hypertensive subjects according to old (JNC 7, 2003) guidelines. Only 27 subjects (12.8%) were diagnosed hypertension cases, while 122 (58%) subjects were having undiagnosed HTN. HTN was more common in males, compared to females, but obesity was more common in females compared to males. Obesity indices, age, height and body weight were significantly correlated with blood pressure. Increasing age, central obesity (high waist circumference and high waist-height ratio) and male gender was found to be significant risk factor for HTN. Conclusions: Burden of HTN is found to be much higher than before when new AHA (2017) HTN guidelines are applied for classification in Indian subjects. There is urgent and increased need to manage measures like lifestyle modifications, diet management and regular exercise to prevent obesity and HTN. © 2020, Association of Physiologists and Pharmacologists of India. All rights reserved.
Physical fitness and diabetes
(NLM (Medline), 2023) Hanjabam Barun Sharma; Sahil Madan; Sanjay Kalra
Physical fitness is an essential part of, and an important means of, ensuring and maintaining good health. Exercise is a physical activity which is designed for improvement or maintenance of physical fitness. Pursuit for fitness should be an integral aspect of one's lifestyle, and hence one should engage in regular physical activity, exercises, games, sports and martial arts. Persons living with diabetes often find it challenging to pursue a proper exercise regimen in an effective, yet safe, manner. In this communication, we suggest a strategy to kick start a physical fitness regimen that one can adhere to. This simple suggestion will be helpful not only for persons living with diabetes and other chronic diseases, but for their health care providers as well.
Recording of length-tension relationship of elbow flexors and extensors by varying elbow angle in human
(Association of Physiologists and Pharmacologists of India, 2020) Hanjabam Barun Sharma; Arani Das; Prashant Tayade; Kishore K. Deepak
Objectives: The concept of length-tension relationship in skeletal muscle can be studied in a living person by demonstrating the relationship between isometric strength and joint angles. There is lack of an effective practical module to demonstrate this concept in living person, hence the study was planned. Materials and Methods: A simple, feasible and novel practical is designed using a custom-made isometric elbow flexion-extension exercising instrument, in which isometric elbow strength is measured using a dynamometer against various elbow joint angles measured using a goniometer. Result: Elbow isometric strength varied across its joint angles and was maximum at the optimum angle, which was 90°. Conclusion: We propose a simple and novel practical to understand the skeletal muscle length-tension relationship in a living person partly, by using the angle-strength relationship for undergraduate teaching in physiology. © 2020 Published by Scientific Scholar on behalf of Indian Journal of Physiology and Pharmacology.
Role of CTLA4 A49G polymorphism in systemic lupus erythematosus and its geographical distribution
(BMJ Publishing Group, 2019) Vikas Kailashiya; Hanjabam Barun Sharma; Jyotsna Kailashiya
CTLA-4 (cytotoxic T-lymphocyte-associated protein-4) or CD152 is an inhibitory receptor expressed constitutively on CD4+ CD25+ T regulatory lymphocytes and transiently on activated CD4+ and CD8+ T lymphocytes. Its inhibitory function promotes long-lived anergy in immune cells and prevents autoimmunity. Therefore, it plays a crucial role in T cell-mediated autoimmunity, and thus in susceptibility to autoimmune diseases, including systemic lupus erythematosus (SLE). It is encoded by CTLA4 gene in humans. AtoG polymorphism at position +49 of CTLA4 gene is the only polymorphism which changes amino acid sequence from alanine to threonine in the leader sequence, which may affect the function of CTLA-4. Association of CTLA4 polymorphisms with SLE has been investigated in several reports in different ethnic populations from different countries, which have shown highly inconsistent findings. In this review, we have compiled previous studies which have reported the association of CTLA4 A49G polymorphism in SLE and its geographical distribution. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
SPORTS AND EXERCISE MEDICINE IN INDIA: LOOKING BEYOND INJURY
(Wydawnictwo Naukowe Uniwersytetu Szczecinskiego, 2022) Hanjabam Barun Sharma
Sports Medicine (SM) is a new specialty in India which has been often projected as dealing only with treating musculoskeletal (MSK) sports injuries. With adequate training in medical-clinical and interventional physiological sciences, SM physicians have an important role to play as an essential part of the multidisciplinary and multispecialty team in the fight against the rise of physical inactivity, sedentary lifestyle and non-communicable diseases. Dope-free sports performance enhancement is another important aspect, which needs beyond the MSK centric approach of sports medicine. There is need for awareness and overall development of this unique specialty, with contribution from government side and non-government organizations. © The Author(s) 2022.
Sports and exercise medicine: An emerging medical speciality
(Scientific Scholar, 2022) Hanjabam Barun Sharma; Jyotsna Kailashiya
Sports and exercise medicine (SEM) is a relatively new medical speciality that comprises sports medicine (overall medical care of active and exercising individuals for performance optimisation and improvement) and exercise medicine (use of physical activity and exercise for health and fitness promotion and illness and injury management). Physicians with specialisation in SEM and clinical and interventional physiology (CIP) have key roles to play in combating physical inactivity and non-communicable diseases which are threatening to become epidemic proportions on the one hand, and dismal sports performance and rising doping menace on the other hand. This review provides information regarding SEM as an emerging medical speciality, its domains, key roles of the SEM and CIP physicians and future prospects of this field. CIP along with exercise physiology, as the foundation of SEM, is discussed in this review. © 2022 Published by Scientific Scholar on behalf of Indian Journal of Physiology and Pharmacology.
Telomerase based anticancer immunotherapy and vaccines approaches
(Elsevier Ltd, 2017) Chahal Kailashiya; Hanjabam Barun Sharma; Jyotsna Kailashiya
Telomerase is a Reverse Transcriptase that maintains the telomere length. It is absent in most somatic cells but is found in stem cells, germ cells and around 90% of cancers. It plays a crucial role in developing and maintaining cancer cells. Telomerase, a HLA class-I antigen, is able to stimulate cell mediated immune response by inducing cytotoxic T-cells. This property of telomerase is being exploited in targeting cancers by host's own immune responses; stimulated by various Human Telomerase Reverse Transcriptase (hTERT) derived vaccines. Many approaches and studies including clinical trials have shown effective anticancer responses of these vaccines, without toxicity to non cancer cells. In this article we have compiled different hTERT based anticancer immunotherapy approaches, vaccines and their performances. © 2017 Elsevier Ltd
The anthropometric correlates for the physiological demand of strength and flexibility: A study in young Indian field hockey players
(Journal of Clinical and Diagnostic Research, 2017) Hanjabam Barun Sharma; Jyotsna Kailashiya
Introduction: Optimal strength and flexibility are essential for performance enhancement and injury prevention in hockey, and anthropometry is known to influence these parameters. Aim: To find anthropometric correlates for strength and flexibility score in young Indian field hockey players. Materials and Methods: Thirteen female and 19 male subjects volunteered for the study. Selected anthropometric variables: lengths, breadths, girths and body composition; strength and sit and reach score were measured for each subject. Results: Males were taller, leaner and stronger with longer upper limbs and broader chests. With few exceptions, taller, heavier and leaner players with longer trunks and limbs, broader chest and hip, and bulkier arms and lower limbs had stronger grip, back, upper and lower limbs. Heavier and taller players with longer trunk and more percentage of body fat were more flexible. Also, the stronger players had more percentage body fat and body mass index, which might be due to the strong positive correlation of percentage body fat and body mass index with fat free mass. Conclusion: Anthropometric variables, especially heights, breadths and body composition, show significant correlation with strength and flexibility, and hence may serve as monitoring tool and for talent identification. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.