Browsing by Author "K.K. Narang"

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Aluminium(III), chromium(III) and iron(III) complexes with 5-iodouracil and 5-iodouracil-histidine and their antitumour activity
(2009) Vinod P. Singh; Shweta Singh; K.K. Narang; D. Bhattacharya
Complexes of the type [Al(HL)(OH)Cl2], [M(HL)(OH)2 Cl] and [M′(HL)(L′)(OH)Cl], where HL = 5-iodouracil; HL′ = histidine; M = Cr(III), Fe(III) and M′ = Al(III), Cr(III), Fe(III), were synthesized and characterized. The complexes are polymeric showing high decomposition points and are insoluble in water and common organic solvents. The μeff values, electronic spectral bands and ESR spectra suggest a polymeric 6-coordinate spin-free octahedral stereochemistry for the Cr(III) and Fe(III) complexes. 5-Iodouracil acts as a monodentate ligand coordinating to the metal ion through the O atom of C(4) = O while histidine through the O atom of -COO- and the N atom of -NH2 group. In vivo antitumour effect of 5-iodouracil and its complexes was examined on C3H/He mice against P815 murine mastocytoma. As evident from their T/C values, Cr(III) and Fe(III) complexes display significant and higher antitumour activity compared to the 5-iodouracil ligand. The in vitro results of the complexes on the same cells indicate that Cr(III) and Fe(III) complexes show higher inhibition on 3 H-thymidine and 3H-uridine incorporation in DNA and RNA replication, respectively, at a dose of 5 μg/mL.
Complexes Of Zn(II), Cu(II), Ni(II) And Co(II) Tetrathiocyanato Mercurates(II) With Hydrazides And Their Biological Activity
(1985) K.K. Narang; Meena Singh
A new series of bimetallic tetrathiocyanate complexes of the type MM’(SCN)4.L, M = Zn(II), Cu(II), Ni(II), Co(II), M’ = Hg and L = benzoylhydrazide (BH), oxaldihydrazide (ODH) and malondihydrazide (MDH) have been synthesized in dilute ethanolic medium. The 1:1 metal:ligand complexes, which have been characterized by elemental analysis, magnetic moment data, electronic and infrared spectra, are insoluble in water as well as common organic solvents and decompose above 250°C without melting. The ligands act as bidentate coordinating species in the complexes. Some of these bimetallic complexes have been tested against Escherichia coli and Klebsillea pneumoniae bacteria and Aspergillusflavus, Penicillium sp. fungi, and were found to be biologically active. © 1985, Taylor & Francis Group, LLC. All rights reserved.
Effect of carboxymethyl-cellulose on the properties of cement
(Elsevier BV, 2003) P.C. Mishra; V.K. Singh; K.K. Narang; N.K. Singh
Effect of sodium salt of carboxymethyl-cellulose (CMC) on the properties of ordinary Portland cement has been studied. Variations in setting time, heat of hydration, compressive strength, fracture toughness have been determined. FT-IR and XRD techniques have been employed to determine the phase compositions of the material. Interaction between CMC and cement hydrated products takes place and new phases are formed in the presence of water, which lead to the formation of strong bonds and sealing of the pores in the resulting products, causing decreased water absorption and more corrosion resistance as compared with the ordinary Portland cement. © 2002 Published by Elsevier B.V.
Effect of HPMC on the properties of cement
(2002) N.K. Singh; P.C. Mishra; V.K. Singh; K.K. Narang
The HPMC (hydroxypropyl methyl cellulose) has been taken as an additive, which retard the setting of cement. The cement-HPMC mixes were prepared having improved compressive strength, tensile strength and fracture toughness in comparison to ordinary Portland cement at late curing ages. The heat of hydration of different cement-HPMC mixes show that the lower contents of HPMC interact with hydrated cement at early curing while higher content at late. The cement-HPMC mix has been found to have better corrosion resistance than OPC in H2SO4, HCl and sea-water. Spectroscopic studies suggested that HPMC bind with free lime. X-ray diffractrogram of 91days hydrated cement-HPMC mix displays some new peaks as well as few peaks appeared with low intensities showing interaction of HPMC with hydrated cementitious phases.
Effect of sulphanilic acid on portland cement
(1979) V.K. Singh; K.K. Narang; M.M. Ali
The effect of sulphanilic acid on the setting of Portland cement has been investigated and it has been observed that with the increasing concentration of sulphanilic acid from 0.5 to 3.0%, the setting time of cement increases. The strength of 1:3 cement/sand mortar containing the above additive, decreases slightly on seven days. The workability of the above mix increases with the increasing amount of the additive and thus decreasing the water requirement. © 1979 Taylor & Francis Group, LLC.
Effects of hydroxyethyl cellulose and oxalic acid on the properties of cement
(2003) N.K. Singh; P.C. Mishra; V.K. Singh; K.K. Narang
Effects of hydroxyethyl cellulose (HEC), oxalic acid and their binary mixtures {1:1, 1:2, 1:3 and 1:4 (by mass)} on the properties of ordinary Portland cement have been studied using up to 4% admixtures. Variations in setting time, heat of hydration, strength, hardness and fracture toughness have been determined. FT-IR and XRD have been utilized to determine the phase compositions of the material. Corrosion resistance against H2SO 4, HCl and seawater has been studied by determining the loss in mass of cement mortars. It was found that HEC acts as a retarder and oxalic acid as an accelerator. The binary mixture (1:3) has increased the heat of hydration, strength, hardness, fracture toughness and corrosion resistance. Interaction between HEC, oxalic acid and cement hydration products takes place, and new phases are formed in the presence of water, which lead to the formation of stronger bonds and the sealing of the pores in the resulting product causing decreased water absorption as compared to ordinary Portland cement. © 2003 Published by Elsevier Science Ltd.
Fe(II), Co(II), Ni(II) AND Cu(II) PERCHLORATE COMPLEXES WITH AMINOPYRINE
(Indian Academy of Sciences, 1981) S.V. Tatwawadi; A.P. Sihgh; K.K. Narang
Aminopyrine complexes with metatl (II) perchlorate of the types [M(AMP),2H,O] (CIO4)2. [M(AMP)2](ClO4)2 and [M(AMP)2H,O](CIO4h, where M = Fe(II), Co(II), Ni(II) and Cu(II) AMP = amirtopyrine, were prepared and characterised by analysis, molar conductanc;, mognenc measurements, electronic and infrared spectral studies. © (1981), (Indian Academy of Sciences). All Rights Reserved.
Ir study of monocalcium aluminate-organic acid compounds
(1980) M.M. Ali; K.K. Narang; V.K. Singh
The nature of formation of compounds between monocalcium aluminate and organic acids such as salicylic, anthranilic and sulphanilic acid taken in the ratio of 1: 1, 10: 1 and 100: 1 respectively was studied by infra-red spectroscopy. Sallcvlic and anthranilic acids deprotonate to form resonanc∼ stabilized chelate structures with hydrated alumina while sulphanillc acid deprotonates to form bridged complexes in the cementitious phase. © 1980 Taylor & Francis Group, LLC.
N-acetyl, N′-benzoyl hydrazine complexes of cobalt(II), nickel(II) and copper(II)
(1973) R.C. Aggarwal; K.K. Narang
N-Acetyl, N′-benzoyl hydrazine (ABH) complexes of the type M(ABH-H)2. 2H2O, M = CoII and NiII and Cu(ABH-2H) have been prepared and characterised by analysis, visible and infrared spectral data and magnetic measurements. The complexes are spin free. ABH appears to be tridentate in octahedral CoII and NiII complexes and quadridentate in square planar CuII complex. Chelation occurs through enolization of one or both the carbonyl groups. © 1973.
Salicylaldehyde salicylhydrazone complexes of some transition metal ions
(1974) K.K. Narang; A. Aggarwal
Salicylaldehyde salicylhydrazone (SSH) complexes M(SSHH)2, M = Cu(II), Co(II), Mn(II), VO(IV), TiO(IV); M′(SSH2H), M′ = Cu(II), Ni(II), Co(II), and Cu1(SSHH) have been synthesised and characterised by analysis, infrared and electronic spectra and magnetic measurements, They are insoluble in common solvents and decompose above 250°C without melting. Subnormal magnetic moments have been observed in some of them. Comparison of electronic absorption bands of SSH and metal complexes show the presence of ligand-metal charge transfer bands. Cu(II) complexes are square planar while Ni(II) and Co(II) complexes have octahedral stereochemistry. In M′ (SSH2H) complexes, infrared spectra indicate the involvement of -OH, >CO and >CN groups. In others, only -OH and >CN appear bonded. Metal-metal interactions via oxo-bridge structures have been discussed in the light of magnetic, electronic and infrared data. © 1974.
Studies on complexes of Co(II), Ni(II), Cu(II), and Cd(II) with acetophenone and 4-hydroxyacetophenone 4-aminobenzoylhydrazones
(2003) B. Singh; K.K. Narang; Rachana Srivastava
Metal(II) complexes of the types [M(L)Cl2(H2O)] and [M(L′)2Cl2] [M = Co(II), Ni(II), Cu(II) and Cd(II), L = acetophenone- 4-aminobenzoylhydrazone (APABH), NH2C6H4CONHN=C(CH3)C 6H5 and L′ = 4-hydroxyacetophenone 4-aminobenzoylhydrazone (HAPABH), NH2C6H4CONHN=C(CH3)C 6H4OH were prepared and characterized by elemental and thermal analyses, molar conductance, magnetic susceptibility, infrared, NMR and electronic spectral studies. Some of the complexes were screened against E. coli, and Aspergillus niger for biological activity. The antibacterial activity of hydrazones and their complexes increases with increase of the concentration of solutions. At each concentration copper(II) complexes are more active than the Zinc(II) complexes with both hydrazones. The antifungal activity of the complexes is less than their parent ligands.
Studies on complexes of Co(II), Ni(II), Cu(II), and Cd(II) with acetophenone and 4-hydroxyacetophenone benzoylhydrazones
(2001) B. Singh; K.K. Narang; Rachana Srivastava
Metal(II) complexes of the types [M(L)2Cl2] · H2O and [Cu(4-HOABH)SO4(H2O)2] [M = Co(II), Ni(II), Cu(II) and Cd(II), L = acetophenone benzoylhydrazone (ABH), C6H5CONH-N=C(CH3)C6H5 and 4-hydroxyacetophenone benzoylhydrazone (4-HOABH), C6H5CONHN=C(CH3)C6H4OH], were prepared and characterized by elemental and thermal analyses, molar conductance, infrared, ESR and electronic spectral studies. Some of the complexes were screened against E. coli and Aspergillus niger for biological activity.
Studies on complexes of cobalt(II), nickel(II), copper(II), and cadmium(II) with acetophenone and 4-hydroxyacetophenone oxaloyldihydrazones
(2001) B. Singh; K.K. Narang; Rachana Srivastava
[No abstract available]
Studies on complexes of cobalt(II), nickel(II), copper(II), and cadmium(II) with acetophenone and 4-hydroxyacetophenone salicyloyl and isonicotinoylhydrazones
(2002) B. Singh; K.K. Narang; Rachana Srivastava
Metal(II) complexes of the types [M(L)mCl2(H2O)n] and [Cu(L′)SO4(H2O)2] [M=Co(II), Ni(II), Cu(II) and Cd(II), L=acetophenone salicyloylhydrazone (ASH) OHC6H4CONHN=C(CH3)C6H 5, m=2, n=2; 4-hydroxyacetophenone salicyloylhydrazone (4-HOASH), m=2, n=0; acetophenone isonicotinoylhydrazone (AINH), NC5H4CONHN=C(CH3)-C6H 5, m=1, n=2; 4-hydroxyacetophenone isonicotinoylhydrazone(4-HOAINH), NC5H4CONHN=C(CH3)-C6H 4OH, m=1, n=2, and L′= 4-HOAINH and 4-HOASH] were prepared and characterized by elemental and thermal analyses, molar conductance, magnetic susceptibility, infrared, electronic, NMR, ESR and X-ray powder diffraction studies. Some of the complexes were screened against E. coli and Aspergillus niger to explore their biological activity.
Synthesis and characterization of some bivalent transition metal complexes with acetyl acetone mono-benzoylhydrazone and acetylacetone mono - isonicotinc ylhydrazone
(1994) K.K. Narang; V.P. Singh
Acetyl acetone mono-benzoyl hydrazone, PhCONHN= C (Me) CH2C(Me)G (LH), and acetyl acetone mono-isonicotinoylhydrazone, NC5H4CGNHN =C(Me)CH2C(Mie)0 (L'H), complexes of the type LML2J and LML2'] (M = Co(II), Ni(ll), Cu(ll) or Zn(ll)) have been prepared and characterized. The ligands form monobasic, four-coordinate complexes and chelate via enolate and imine. The E.S.P. spectra of the Cu(II) complexes suggest a square co-planar stereochemistry. © 1994, Taylor & Francis Group, LLC. All rights reserved.
Synthesis and characterization of some lanthanoid complexes of salicylaldehyde salicyloyl hydrazone
(2002) T.R. Rao; Sabita Shrestha; K.K. Narang
Some lanthanoid complexes of the types, [Ln(ssh)(H2O)n].H2O and [Ln′(Hssh)(X)(H2O)3].H2O, where Ln = Y, La, Nd, Gd, Tb and Dy; Ln′= Pr/Sm for X = NO3/Cl and H3ssh = salicylaldehyde salicyloyl hydrazone, have been synthesized and characterized by elemental analyses, molar conductance, magnetic susceptibility, infrared, electronic and 1H NMR spectral data. Selected complexes have also been studied on the basis of their solid state electrical conductivity, band gap, and powder X-ray diffraction data. The complexes, except those of the Pr and Sm, are polymeric in nature showing high decomposition points. Dehydration study indicates the presence of water molecules both in the lattice and coordination sphere of the complex metal ions. IR and 1H NMR spectral data suggest trinegative tetradentate and dinegative tridentate coordination of H3ssh in the complexes. The chloro and nitrato groups are found to coordinate to the metal ion as monodentate and bidentate-chelating species respectively. Solid state electrical conductivity data at various frequencies show semi-conducting nature of the complexes. Optical band gap studies show the complex [Gd(ssh)(H2O)3].H2O to be a direct band gap semi-conducting material with a band gap of 2.64 eV. Powder X-ray diffraction patterns show orthorhombic structure for most of the complexes. Various polyhedral geometries such as distorted octahedron, pentagonal bipyramid and distorted square antiprism are tentatively proposed for the complexes.
Synthesis and characterization of Zn(II), Cu(II), Ni(II) and Co(II) complexes with N,N-diacetyloxaldihydrazide and N,N-diacetylmalon-dihydrazide
(1987) K.K. Narang; M.K. Singh
The ligands N,N-diacetyloxaldihyclrazide (DAODH), (CCNHNHCOCH3)2 and N,N-diacetylmaiondinyorazide (DAMDH), CH2CONHNHCOCH3)2, form 1:1 metal:ligand complexes of the types M(DODH-2H).nH20 and M(HNMDH-2H).nH20 where M =Zn(II), Cu(II), Ni(II), Co(II) and n - 0, 1, 2. The complexes have been cnaracterized by elemental analysis, electronic, IR and magnetic moment data. The complexes are insoluble in common organic solvents except Cu(DAODH-2H).2H20 and Ni(DAODH-2H).2H20 which are partially soluble in DMF and DMSO. Cu(II) complexes are square planar while Co(II) and Ni(Il) complexes are octahedral, IR data show that both DAODH and DAMDH behave as tetradenrate ligands bonding through C-O and N-H groups. © 1987 by Marcel Dekker, Inc.
Synthesis and spectral studies of copper(II) sulfate complexes with some acetophenone acylhydrazones
(Marcel Dekker Inc., 1999) B. Singh; Rachana Srivastava; K.K. Narang; V.P. Singh
[No abstract available]
Synthesis and spectral studies of zinc chloride complexes with some acetophenone and 4-hydroxy-acetophenone acylhydrazones
(Marcel Dekker Inc., 2000) B. Singh; Rachana Srivastava; K.K. Narang
[No abstract available]
Synthesis and structural studies of some lanthanide complexes of salicylaldehyde anthranoyl hydrazone
(2002) T.R. Rao; Sabita Shrestha; Archana Prasad; K.K. Narang
Lanthanide complexes of the types Ln(sah)(OAc)·xH2O and Ln′(Hsah)2(X)·xH2O [Ln=Y, La, Nd, Gd, Tb and Dy; Ln′=Pr and Sm, X=NO3 and Cl; H2sah=salicylaldehyde anthranoyl hydrazone were synthesized and characterized by various physico-chemical techniques. The complexes are coloured and highly soluble in methanol, DMSO and DMF. Dehydration studies indicate the presence of both lattice-held and coordinated water molecules. IR, electronic and 1H NMR spectra have been recorded to establish the bonding sites of the ligand. Solution-state conductance measurements indicate the non-electrolytic nature of all of the complexes while solid-state electrical conductivity studies show Nd(sah)(OAc)·4H2O to be a semiconductor. Optical band gap measurements show the Pr, Sm and Dy complexes are direct band gap materials. X-ray diffraction patterns of selected complexes indicate orthorhombic structures.