Browsing by Author "L. Usha"

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Humoral immunity in pediatric Kalaazar patients in India
(1997) L. Usha; A. Dikshit; D.S. Singh; S. Sunder; Z. Ali; R.M. Gupta
The study included 20 patients of Kalaazar in children and 20 healthy children of same age group. Mostly patients were males (75%) and in age group of 3 to 10 years. Humoral immunity was assessed by total serum protein, immunoglobulin estimation and circulating immune complexes. Significant hyperproteinemia was found in patient group as compared to control (p<.001). Ninety percent children had increased IgG above 1600 mg/dl (Mean 2392 ± 715.11 mg/dl). Similarly serum IgM and IgA were also significantly raised in comparison to controls (IgA 178 ± 74 59 mg/dl IgM 194.5 ± 89.8 mg/dl). Except one patient almost all had significant increase in circulating immune complexes (79 78 ± 22.55%). None of the patients had glomerulonephritis, vasculitis or arthritis.
Synthesis and antimicrobial activities of N-mannich bases of 3-[4-sulphadiazinyl]-isatin and derivatives
(1997) Surendra N. Pandeya; L. Usha; Alka Pandey; S.K. Bajpai
Isatins (1) have been condensed with sulfadiazine (2) to yield 3-sulfadiazinyisatins (3). Mannich condensation on 3 in presence of CH2O and secondary amines furnished 3-aminomethyl analogs (4) which were evaluated as antimicrobical agents.