Browsing by Author "Lalit Kumar Lal Das"

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Chemical constituents of Anisodus luridus roots and their antimicrobial screening
(Scientific Publishers, 2015) Mradul Verma; Lalit Kumar Lal Das; Mayank Gangwar; Mahendra Sahai; Gopal Nath; Tryambak Deo Singh
The weak base and strong base fractions were separated from methanolic extract of roots of Anisodus luridus. Chromatographic resolution of both fractions yielded compounds 1-5 which were characterized as β-sitosterol (1), esculetin (2), β-sitosterol-β-D-glucoside (3), apohyoscyamine (4) and hyoscyamine (5) with the help of spectroscopic analysis. Four compounds, 1-4 were isolated from A. luridus for the first time. The weak base, strong base and isolated constituents were screened against six microbes viz. E. coli, S. aureus, E. faecalis, C. albicans, C. tropicalis and C. krusei. Weak base, strong base and isolated pure compounds exhibited their potential against these microbes. © 2015 Scientific Publishers.
Three new acyltyramines from Anisodus luridus Link et Otto (Solanaceae)
(Taylor and Francis Ltd., 2016) Lalit Kumar Lal Das; Mradul Verma; Mahendra Sahai
Three new acyltyramines, N-[2-(4-hydroxyphenyl)ethyl]hentriacontanamide (1), N-[2-(4-hydroxyphenyl)ethyl]nonacosanamide (2) and N-[2-(4-hydroxyphenyl)ethyl]heneicosanamide (3) have been isolated from n-hexane extract of leaves of Anisodus luridus (Solanaceae). Successive extraction of defatted leaves of A. luridus with methanol afforded a residue on removal of solvent under reduced pressure. Residue was partitioned by means of chloroform and n-butanol. Chromatographic resolution of n-BuOH extract afforded six known compounds, apigenin (4), luteolin (5), quercetin (6), quercetin 3-O-α-l-rhamnoside (7), kaempferol 3-O-α-rhamnoside (8) and quercetin 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (9). The structures of the isolated compounds were assigned with the help of spectroscopic techniques. This is the first report of isolation of these compounds from this plant. © 2016 Informa UK Limited, trading as Taylor & Francis Group.