Browsing by Author "S.P. Dixit"

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Alloxan-induced diabetes in rabbits and effect of a herbal formulation D-400
(1994) G.P. Dubey; S.P. Dixit; A. Singh
Adult male rabbits injected with alloxan (50 mg/kg, i.p.) were divided into two groups of nine each. One group received placebo and the other group an aqueous suspension of D-400, at the dose of 1 gm/kg body weight orally daily for 36 weeks. Blood glucose, blood urea and serum creatinine were estimated initially and at every 6-weekly intervals. At the end of 36 weeks D-400 significantly prevented the rise in blood urea and serum creatinine levels as compared to the control. Although a rise in blood sugar was noticed in both the groups, the level of blood sugar after 36 weeks was significantly lower in the D-400 treated group. This shows the favourable response of D-400 against alloxan-induced renal damage and hyperglycaemia.
Management of attention deficit/hyperactivity disorder - Use of an effective paradigm
(2002) S.P. Dixit; M.N. Pandey; G.P. Dubey
The management of ADHD poses a great problem before the psychologists, psychiatrists and different behavioural scientists. The multi-model approach, combining pharmacologic with different non-pharmacologic interventions, is more effective than any form of therapy. In the present study the theta feedback, a non-pharmacologic technique, has shown beneficial role among the low medicated ADHD cases. The present study also signifies the role of multi-model intervention in the management of ADHD.
Role of Seabuckthorn (Hippophae rhamnoides) in the maintenance of cardiovascular homeostasis following cold stress
(Natural Remedies Private Limited, 2003) G.P. Dubey; A. Agrawal; S.P. Dixit
Objective: To study the beneficial role of Seabuckthorn (Hippophae rhamnoides) in the maintenance of cardiovascular homeostasis following cold stress. Materials and Methods: The effect of the alcoholic extract of Seabuckthorn in the daily oral dose of 500 mg was studied on various electrophysiological and neurochemical parameters following cold stress among the positive cold stress responders (human subjects) continuously for 3 months. Results: The average differences in cardiovascular responses like systolic and diastolic blood pressure, and pulse rate that were found to be raised following cold pressor test, minimized following three months oral administration of Seabuckthorn. Further, the psychophysiological parameters like occipito frontalis EMG and galvanic skin resistance also regulated under drug treatment. The serotonin and plasma cortisol levels were also modified following oral administration of Seabuckthorn. Conclusion: Seabuckthorn exhibited beneficial effects to reduce the cardiovascular reactivity following cold stress and thus it enhances the stress tolerance capacity as well as better adaptation towards stress.