Title: Cumulative influence of immunogenic factors, genetic variations, and protein modulations in subacute sclerosing panencephalitis (SSPE): A narrative review
| dc.contributor.author | Nikhil Pandey | |
| dc.contributor.author | Niraj Kumar Srivastava | |
| dc.contributor.author | Anand Kumar | |
| dc.contributor.author | Ibrahim Hussain | |
| dc.contributor.author | Deepika Joshi | |
| dc.date.accessioned | 2026-02-09T04:39:07Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | Subacute sclerosing panencephalitis (SSPE) is a progressive and catastrophic neurodegenerative disorder due to persistent infection with the aberrant measles virus in the brain. The exact etiology of SSPE is still unknown, and early diagnosis remains a challenge, especially with the atypical presentations. The pathogenesis of SSPE involves a complex interplay between viral factors and immunological response of the host. The presenting review demonstrates an extensive glimpse of the immuno-genetics of SSPE, exploring the single-nucleotide polymorphisms (SNPs), genetic risk factors and immune responses that influence susceptibility and disease progression. © 2024 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd. | |
| dc.identifier.doi | 10.1111/ncn3.12861 | |
| dc.identifier.issn | 20494173 | |
| dc.identifier.uri | https://doi.org/10.1111/ncn3.12861 | |
| dc.identifier.uri | https://dl.bhu.ac.in/bhuir/handle/123456789/49148 | |
| dc.publisher | John Wiley and Sons Inc | |
| dc.subject | chemokines | |
| dc.subject | cytokines | |
| dc.subject | genetic markers | |
| dc.subject | measles virus | |
| dc.subject | microRNAs | |
| dc.subject | subacute sclerosing panencephalitis | |
| dc.title | Cumulative influence of immunogenic factors, genetic variations, and protein modulations in subacute sclerosing panencephalitis (SSPE): A narrative review | |
| dc.type | Publication | |
| dspace.entity.type | Review |