Cadmium-induced inhibition of brain monoamine oxidase in the freshwater catfish

Abstract

The freshwater catfish Clarias batrachus (L.), exposed to 50 ppm of cadmium (Cd) chloride for a period of 135 days exhibited marked inhibition of brain monoamine oxidase (MAO) (p<0.001). The retarded gonadal growth observed in the present study suggests that Cd may be capable of creating imbalance in the aminergic activity of the hypothalamus, which modulates the secretion and release of gonadotropins. © 1984 Birkhäuser Verlag.