Browsing by Author "Bhatnagar, Atul"
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Publication A comparative evaluation of neurophysiological activity, active tactile sensibility and stereognostic ability of complete denture prosthesis, and implant-supported prosthesis wearer�A pilot study(John Wiley and Sons Inc, 2022) Bhattacharjee, Bappaditya; Saneja, Ritu; Bhatnagar, Atul; Verma, Ashish; Soni, Romesh; Singh, Ankita; Dubey, PavanAim: The study aimed to evaluate the effect of implant-supported prosthesis in completely edentulous participants in terms of osseoperception ability, neural activity, and stereognostic ability in comparison to removable prosthetic options. Materials and Methods: A total sample of 18 patients, irrespective of gender and age were allocated into three groups according to the three-treatment protocol (upper and lower complete denture, upper complete denture opposing lower implant-retained overdenture, implant-supported fixed prosthesis in both arches). Four weeks after completion of the treatment procedure active tactile sensibility (ATS) was checked by using varying thicknesses (12, 40, 80, 100, 200 ?) of articulating foils and papers. Functional magnetic resonance imaging (fMRI) was performed to record neurophysiological activity in cerebral cortex in all the participants. Various forms of test pieces (heat cure acrylic resin) were used to evaluate stereognostic ability. Data regarding the neurophysiological activity were analyzed by using Krushkal�Wallis test and p ? 0.05 was considered to be statistically significant. Data from stereognostic ability test procedure and ATS were compared by using chi-squared test and p ? 0.05 was considered to be statistically significant. Results: Statistically significant difference was found in between the articulating foils in terms of true negative responses as the foil thickness increased in participants wearing complete denture in both the arches (p�=�0.004) and implant-supported fixed prosthesis in both the arches (p�=�0.010). Participants in implant-supported fixed prosthesis group showed significantly more activation in primary motor cortex (right side), somatosensory cortex (left side), angular gyrus (both sides), temporal lobe (left) compared to other groups. No significant difference found in thalamus and premotor cortex region in between the participants of different groups. No statistically significant difference found in between the groups in terms of true responses identifying correct shapes. Mean number of correct responses in stereognostic ability test were 4.16 (83.33%), 3.5 (70%), 3.83 (76.66%) for participants of complete denture group, upper complete denture opposing lower implant retained overdenture group, and implant-supported fixed prosthesis group, respectively. Conclusion: Primary motor cortex, somatosensory cortex, and other regions of brain were diffusely activated in participants wearing implant-supported fixed prosthesis in both the arches. Less number of false responses were recorded in participants of implant-supported fixed prosthesis group and upper complete denture opposing lower implant-retained overdenture group in ATS test compared to participants wearing complete denture in both the arches. � 2022 Wiley Periodicals LLC.Publication Effect of complete dentures on oral stereognostic ability in edentulous patients: A systematic review(Wolters Kluwer Medknow Publications, 2021) Bhattacharjee, Bappaditya; Saneja, Ritu; Bhatnagar, AtulAim: Oral stereognosis is an important sensation for a human being to percept any type of materials that are introduced in the oral cavity. It is defined as the ability of an individual to recognize objects using only tactile sensation without using vision, audition, balance, somatic function, taste, or smell. The primary purpose of this review was to evaluate the effect of complete dentures on oral stereognostic ability in edentulous subjects. Settings and Design: Systematic review based on PRISMA guidelines. Materials and Methods: A systematic search of the electronic databases like PubMed and Web of Science was done using keywords-'stereognosis,' 'oral stereognosis,' 'complete denture,' and 'complete edentulism.' In addition to this, a manual search of references mentioned in the articles and gray literature was done. Data extraction and assessment were done by two independent reviewers. Statistical Analysis Used: Qualitative analysis. Results: The literature search yielded a total of 61 articles. Thirteen duplicate articles were removed and 36 articles were rejected after initial screening of titles and abstracts. A total of 12 articles were selected for full text reading and 5 of them were included for qualitative analysis. Conclusion: All the included studies showed complete denture treatment therapy improved stereognostic ability in terms of correct identification of test pieces and time taken to identify the objects. There is also a direct relationship between the adaptability of dentures and stereognostic ability. � 2021 EDP Sciences. All rights reserved.Publication Effect of dopaminergic agonist group of drugs in treatment of sleep bruxism: A systematic review(Elsevier Inc., 2022) Bhattacharjee, Bappaditya; Saneja, Ritu; Bhatnagar, Atul; Gupta, PinkiStatement of problem: Various factors are responsible for sleep bruxism; however, whether the dopaminergic agonist group of drugs is effective in the treatment of sleep bruxism is unclear. Purpose: The purpose of this systematic review was to evaluate the effect of the dopaminergic agonist group of drugs in controlling sleep bruxism in comparison with no treatment or placebo-controlled treatment. Material and methods: Two electronic databases, PubMed and Cochrane Central, were searched by using the keywords bruxism, sleep bruxism, dopamine, and dopamine agonist. After screening titles and abstracts, only those articles which met predefined inclusion criteria were selected for full-text assessment. Clinical trials using the dopaminergic agonist group of drugs as a treatment approach to sleep bruxism were included. Results: The literature search yielded a total of 64 articles from the 2 electronic databases (PubMed, 53; Cochrane Central, 11). After removal of the duplicates (n=8), the initial screening of titles and abstracts was performed by 2 independent reviewers, removing 46 articles. A total of 10 articles were selected for full-text reading, and 4 studies were included for qualitative analysis. Conclusions: Levodopa (L-DOPA) and Bromocriptine showed decrease in root mean square value in electromyography per bruxism burst (P<.001) and 20% to 30% reduction of bruxism episodes during sleep in 2 different studies. However, treatment with bromocriptine led to conflicting result in another study in terms of frequency of bruxism episodes and amplitude of muscle contractions in electromyography (EMG). Bruxism bursts and episodes were also not significantly improved with another dopaminergic agonist group of drugs, Pramipexole (P>.001). Based on the limited evidence and conflicting results, significant conclusions cannot be generated, and further studies are required. � 2020 Editorial Council for the Journal of Prosthetic DentistryPublication Effect of Two Different Impression Techniques on Masticatory Performance of Complete Denture Wearers: A Systematic Review(Jaypee Brothers Medical Publishers (P) Ltd, 2021) Nagarajan, Nachammai; Bhattacharjee, Bappaditya; Singh, Ankita; Bhatnagar, AtulAim and objective: The aim of this review was to evaluate the efficacy of the masticatory performance of the complete dentures. The objective of this review was to evaluate scientific evidence of the impact of simplified impression technique versus conventional impression technique on masticatory performance of complete denture wearers. Materials and methods: Three electronic databases (PubMed, Web of Science, and Cochrane library) were searched until 30th October 2020, without any publication year limit. Manual search of the references cited in the included studies and gray literature were also included. Randomized clinical trials that assessed objectively the masticatory performance between complete dentures fabricated from two different impression techniques were included. Results: A total of 398 studies were obtained through search in 3 electronic databases (PubMed- 229, Web of Science- 155, and Cochrane library- 14). Qualities of randomized controlled clinical trials were assessed by Cochrane's tool for Systematic Reviews of Interventions. Heterogeneity of data and measurement methods between the studies limited the scope of their meta-analysis. Nine studies remained after the removal of duplicates and screening of titles and abstracts. Applying eligibility criteria remainder three randomized controlled clinical trials were included after removing six studies. Conclusion: No significant difference was found objectively in masticatory performance of individuals wearing complete dentures fabricated either by simplified impression technique or conventional impression technique. � 2021 International Journal of Prosthodontics and Restorative Dentistry. All rights reserved.Publication Efficacy of Arthrocentesis and Stabilization Splints in Treatment of Temporomandibular Joint Disc Displacement Disorder Without Reduction: A Systematic Review and Meta-analysis(Springer, 2023) Bhattacharjee, Bappaditya; Bera, Rathindra Nath; Verma, Arju; Soni, Romesh; Bhatnagar, AtulBackground: Temporomandibular joint disc displacement disorders are a group of temporomandibular disorders beside from other inflammatory disorders and growth related disorders of joint. The purpose of this analysis was to evaluate the efficacy of arthrocentesis procedure in comparison with stabilization splints used for disc displacement disorders without reduction. Materials and Methods: A systematic search was done in electronic databases (PubMed, Cochrane Central, Web of Science). In addition to this hand search of references and grey literatures was done. Qualities of randomized controlled clinical trials were assessed by Cochrane�s tool for Systematic Reviews of Interventions and the Newcastle�Ottawa Scale was followed to assess the prospective and retrospective studies. Outcome variables pain (VAS) and maximum mouth opening were assessed by the software review manager 5.03. Results: A total of five studies were included in the review. Three studies showed greater improvement of symptoms in patients of arthrocentesis group in terms of maximum mouth opening, pain (VAS) value. Two other studies found no significant advantage of arthrocentesis over the other treatment protocol. The meta-analysis resulted in statistically significant difference between outcome variables favouring arthrocentesis group (VAS 1�10) (Mean Difference: 3.10; 95% CI 1.74, 4.45; P�?�.00001, Mean difference: 2.00; 95% CI 0.29, 3.71; P = 0.02). Conclusion: Arthrocentesis showed effective result in terms of increase in mouth opening and reduction of pain level compared to stabilization splint and other non-invasive approaches in patients with disc displacement disorders without reduction. Overall, results supported the rationale of using arthrocentesis in patients with disc displacement disorders without reduction. � 2021, The Association of Oral and Maxillofacial Surgeons of India.Publication Enhancement of Sensorimotor Cortical Adaptation after Dental Implantation in Comparison to the Conventional Denture-Demonstration by Functional MRI at 1-5T(Wolters Kluwer Medknow Publications, 2021) Verma, Aprajita; Bhatnagar, Atul; Kumar, Ishan; Verma, AshishBackground and Purpose: Dental implantation is thought to be associated with enhancement of neuro-cortical sensorimotor activity which has been lost due to an edentulous state. Such changes are either feeble or absent after the placement of a conventional denture. In the present study, we test this hypothesis using blood oxygen level-dependent (BOLD) activity on functional MRI (fMRI) as a bio-surrogate. Materials and Methods: fMRI was performed in 12 consecutive edentulous subjects (mean age = 59.2 years) after the placement of a conventional complete denture (CD) and subsequently after intraoral dental implantation (IOD). The semi-quantitative data of the BOLD activity was compiled to depict the activation seen in both scenarios in six anatomical regions. Statistical analysis was done to evaluate the significance of enhancement in BOLD activity in these regions in patients having an IOD as compared to those having a CD. Results: The enhancement of BOLD activity on fMRI after placement of an IOD was much more significant as compared to that noted with CD. Using Wilcoxon's signed-rank test the nonparametric data showed a significant positive elevation in global and regional assigned mean ranks of BOLD activity. Conclusion: Intraoral implantation leads to a significant elevation in the BOLD activity of the sensorimotor cortex as compared to the placement of a conventional CD. � 2021 Wolters Kluwer Medknow Publications. All rights reserved.Publication Influence of Surface Nano-Structuring on Microstructure, Corrosion Behavior and Osteoblast Response of Commercially Pure Titanium Treated Through Ultrasonic Shot Peening(Springer, 2022) Chauhan, Pankaj; Shadangi, Yagnesh; Bhatnagar, Atul; Singh, Vakil; Chattopadhyay, KausikCommercially pure titanium (Cp-Ti) is a widely accepted material for dental implants. Increases in surface roughness of these implants enhance osseointegration and result in better fixation with bone. Ultrasonic shot peening (USSP) is known to be an effective process of surface modification. This work is concerned with effect of USSP on modifications of the microstructure, surface topography, and corrosion behavior of Cp-Ti. The samples were USSPed for prolonged duration (30�min and 60�min) with both 1-mm and 3-mm diameter 100C6 steel balls. The thermal stability of the USSPed Cp-Ti was studied by stress relieving (SR) treatment at 500�C for 1 h. The surface roughness of the USSPed samples was increased and grains in the surface region were refined to nanoscale. The potentiodynamic polarization study showed significant increases in corrosion resistance of the USSPed samples. Further, enhanced osteoblast response was also observed for USSPed samples with and without SR. � 2022, The Minerals, Metals & Materials Society.Publication Lateral augmentation of the posterior edentulous mandible: A retrospective single arm comparison of ridge split, block bone grafts and guided bone regeneration(John Wiley and Sons Inc, 2022) Nath Bera, Rathindra; Kumar Sharma, Naresh; Bhattacharjee, Bappaditya; Bhatnagar, Atul; Gopalakrishna Naveen Kumar, Puvvadi; Kusumakar, AnantaBackground: A deficient hard and soft tissue at the surgical site is a definitive challenge for dental implant placement. Commonly used procedures for augmentation include block bone grafts, guided bone regeneration, distraction, ridge expansion, ridge split, sandwich osteotomy, etc. The current study evaluates three techniques employed for horizontal augmentation of the mandible. Methods: A retrospective chart review was conducted for patients reconstructed with either block bone (A), guided bone regeneration (B), or ridge split (C) for lateral augmentation of posterior mandible. The primary outcome variables assessed were immediate postoperative bone width and bone width after 4�months, bone gain and resorption. Complications were evaluated as secondary outcomes. ANOVA and post hoc turkey tests were used for statistical analysis. A p-value of <0.05 was considered as statistically significant. Results: A total of 250 patient records were included in the study. Group C had a mean bone gain of 5.8649���0.6520�mm statistically significant from others. Resorption was maximum in Group B 1.1612���0.2821�mm. Iliac crest graft gave a mean 5.7285���0.1823�mm bone gain. Overall no difference in bone gain between particulate or block interposition. Discussion: Grafts from intraoral sites are comparable in terms of resorption. ARS considerably provides better augmentation compared to GBR and onlays. Conclusion: Ridge split followed by onlay block bone grafting provides the best outcomes. Ramus and symphysis grafts are comparable. Iliac grafts are still the best for significant augmentations. Guided bone regeneration suffers maximum resorption. � 2021 The British Association of Oral Surgeons and John Wiley & Sons LtdPublication Long COVID-19: Rehabilitative and Restorative Challenges(Jaypee Brothers Medical Publishers (P) Ltd, 2021) Bhatnagar, Atul[No abstract available]Publication Peri-implant stress distribution assessment of various attachment systems for implant supported overdenture prosthesis by finite element analysis � A systematic review(Elsevier B.V., 2022) Bhattacharjee, Bappaditya; Saneja, Ritu; Singh, Ankita; Dubey, Pavan Kumar; Bhatnagar, AtulBackground: Various attachments like ball, bar-clip, magnetic attachments are used in implant supported overdentures. Finite Element Analysis (FEA) a newly innovated technology has been used in dental implantology to evaluate stress distribution patterns. There is little evidence available regarding the stress distribution in peri-implant region for implant supported overdentures. The purpose of the review was to generate scientific evidence on peri-implant stress distribution in FEA model with different types of attachments employed in implant supported overdentures. Materials and methods: Systematic review was conducted as per the Preferred Reporting Items for Systematic Reviews Guidelines and Meta-Analyses statement (PRISMA). A comprehensive search was undertaken by two reviewers from January 2020 to June 2020 with no year limits to published articles. Only in-vitro FEA studies were included. Following electronic databases were searched for published studies- PubMed, Web of Science. Characteristics of the studies tabulated and analysis of articles was done to compare different attachment systems. Results: Locator attachments showed better stress distribution than ball attachment system in all the studies but one. Two studies showed results in favour of ball attachment compared to bar-clip attachment system when stress was evaluated distal to the implants. No significant difference in terms of stress concentration could be generated between ball versus magnetic/equator versus locator attachment system due to less number of studies and conflicting results. Conclusion: Various studies showed different results due to heterogenicity in selected attachment systems and study designs. Locator attachments showed favourable stress distribution around peri-implant bone than other attachments. � 2022 Craniofacial Research FoundationPublication Response to the letter to the editor regarding �Concerns regarding the published article �Effect of dopaminergic agonist group of drugs in treatment of sleep bruxism: A systematic review� by Bhattacharjee et al. J Prosthet Dent. 2021 Jan 14:S0022-3913(20)30752-6�(Mosby Inc., 2021) Bhattacharjee, Bappaditya; Saneja, Ritu; Bhatnagar, Atul; Gupta, Pinki[No abstract available]
