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- This community brings together the scholarly publications of various departments at Banaras Hindu University (BHU), offering a platform to explore and access the academic and research contributions from each department.
- This community showcases the Project reports submitted by researchers at Banaras Hindu University (BHU), offering a subject-wise compilation of research projects and their outcomes across various disciplines.
- This community showcases the academic contributions of faculty and researchers at Banaras Hindu University (BHU) and provides a year-wise compilation of publications across disciplines.
Recent Submissions
Results of urethral reconstruction in neglected urethral foreign bodies with associated urethral strictures
(SAGE Publications Ltd, 2025) Trivedi, Sameer; Goel, Nitin; Pal, Harish; Reddy, Koti Sridhar; M, Rinaldo; Nayak, Pradeep; Singh, Yashasvi; Kumar, Ujwal
Objective: Urethral foreign bodies with associated urethral strictures are unusual entities. Although few case studies have reported the management of urethral foreign bodies, the management of neglected foreign bodies with resultant urethral strictures has not been addressed in the literature. Materials and Methods: A retrospective review of 15 patients diagnosed with strictures and associated urethral foreign bodies was performed for collection of data, viz., demographic and clinicopathological factors; details of urethral reconstruction procedures; perioperative and postoperative events; and follow-up data. Results: Underlying aetiology was self-insertion for sexual gratification in nine patients (metallic safety pins – 3, wooden splinters – 2, electric cables – 2, and plastic rods in two patients), gunshot injuries with embedded pellets in 4, and iatrogenic foreign bodies in two patients. Three patients had complete urethral obstruction, six had bulbar strictures, four had penile urethral strictures, and two had pan urethral strictures. Seven strictures were managed by primary end-to-end anastomosis, three by augmented roof-strip anastomosis using oral mucosal grafts, while the remaining five patients required augmentation urethroplasty using oral mucosal grafts. The overall success rate of urethral reconstruction was 93.3%. Conclusion: Neglected urethral foreign bodies with associated urethral strictures are uncommon. Surgical management, although challenging owing to an unhealthy local milieu, has satisfactory outcomes. Level of Evidence: Not applicable. © British Association of Urological Surgeons 2025.
The Bottom Line of Personalization: Unravelling the Power of Algorithms and Segmentation Through a Systematic Review
(Sage Publications India Pvt. Ltd, 2025) Shrivastava, Rachit; Dubey, Sujit Kumar
Personalized algorithm is a set of complex mathematical models that use various techniques such as machine learning and data mining. Individuals’ personal information is collected and processed in various ways to create personalized experiences. This article aims to have a thorough outlook of personalization in a varied retail touchpoint. The study initiated the work by conducting comprehensive systematic literature review of personalization by utilizing the techniques of science mapping, performance analysis and formulating the PRISMA model framework. A systematic review was done using two significant databases, Scopus and Web of Science, based on which significant themes were identified. At the end, study judiciously concludes by offering the future research direction to incorporate the technological advancements in the form of big data analysis, Internet of Things, artificial intelligence and humanoid shopping assistant to lay out the adaptation and feasibility of personalization in the omnichannel retailing. © 2025 MDI.
Development of Donor-Acceptor Architecture-Based Potential Theranostic Fluorescent Probes for Alzheimer’s Disease
(American Chemical Society, 2025) Bajad, Nilesh Gajanan; Gajendra T., A.; Sharma, Khushboo; Tapadia, Madhu G.; Kumar, Ashok; Krishnamurthy, Sairam; Singh, Sushil Kumar
The cholinergic deficits and deposition of β-amyloid (Aβ) species are regarded as the key events contributing to the progression of Alzheimer’s disease (AD). Herein, a series of novel donor-acceptor architecture-type potential theranostic agents were designed, synthesized, and evaluated for their potential against cholinesterase (ChE) enzymes and detection of Aβ species, which are primary targets in the development of therapeutics for AD. The optimal compound/probe 18 containing a benzothiazolium fluorophore with a bifunctional electron-donating N-aryl piperazine scaffold exhibited potent inhibitory activities against acetylcholinesterase (AChE; IC50 = 0.172 ± 0.011 μM) and butyrylcholinesterase (BuChE; IC50 = 1.376 ± 0.141 μM). Measurement of fluorescence properties showed that probe 18 exhibited emission maxima (λem) of >610 nm in dimethyl sulfoxide (DMSO) and >590 nm in PBS, suitable for the fluorescence imaging. In vitro studies demonstrated a change in fluorescence characteristics and high binding affinities (18; Kd = 0.731 μM) upon binding with Aβ aggregates. The affinity of probe 18 toward Aβ aggregates was further observed in elavGAL4 > UAS Aβ, the Drosophila larval brain sections, using a fluorescence imaging technique. The in vivo acute oral toxicity evaluation indicated a safety profile of the lead probe 18. Moreover, in vivo behavioral studies including Y-maze and novel object recognition tests signified that the administration of compound 18 improved cognitive and spatial memory impairment at a dose of 10 and 20 mg/kg in the scopolamine-induced cognitive deficit model. © 2025 American Chemical Society.
An Assessment of Smartphone Use on Brainstem Auditory Evoked Potentials in Healthy Young Adults in North India Short Title: Assessing BAEP Changes in Young Smartphone Users
(SAGE Publications Inc., 2025) Seth, Ayushi; Singh, Samir Kumar; Gupta, Anita; Sharma, Hanjabam Barun
Background: A smartphone is an essential part of our daily existence. Smartphones are used by about 5.26 billion people. Purpose: The purpose of this study was to determine how the duration of smartphone use influenced brainstem auditory evoked potentials (BAEPs). Methods: BAEPs were measured using BERAGRAPH in 41 young healthy persons in an observational cross-sectional study. Results: When daily smartphone calling time is 60 minutes, there is a statistically insignificant difference in smartphone usage length (5 years and >5 years) between the two groups among BAEPs. Conclusion: Despite the P-value being insignificant, there is a positive relationship between smartphone use in years and absolute wave latencies and interpeak latencies of brainstem evoked potentials. © The Author(s) 2025.