Browsing by Author "Jain, Gaurav"

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    Evaluation of Machine Learning Models for Ore Grade Estimation
    (Springer Science and Business Media Deutschland GmbH, 2022) Jain, Gaurav; Pathak, Pranjal; Bhatawdekar, Ramesh Murlidhar; Kainthola, Ashutosh; Srivastav, Abhishek
    Geostatistics has been widely used for qualitative estimation of ore deposits for many decades. However, ore quality does not vary uniformly in three dimensions which results in a poor quality estimation with the conventional geostatistical methods. Also, the time required for processing geostatistical data can be substantially high. On the other hand, with the advancement in computational processing power and development of advanced algorithms on artificial intelligence (AI) and machine learning (ML), the requirements of an accurate ore grade estimation in reasonable computation time can be fulfilled. In this paper, the applicability of various machine learning techniques like artificial neural network (ANN), extreme learning machine (ELM), gradient boosted decision trees (GBDT), random forests (RF), support vector regression (SVR) have been discussed for ore grade estimation of different mineral deposits like iron, gold and copper. This study also cross-examines the results of ordinary kriging (OK) and inverse distance weighted (IDW) techniques for qualitative estimation. Correspondingly, statistical parameters such as coefficient of determination (R2) and root mean squared error (RMSE) have also been taken into account for a better understanding of the models. Nowadays, AI/ML techniques are extensively used in multiple fields worldwide, including the mining sector, due to their fast and efficient prediction capability. The investigation of these models highlights the importance of accuracy in predicting the quality of the ore as the latter greatly impacts the economic feasibility of mineral deposits. This study forms a ground for developing new advanced intelligent approaches for improving the accuracy of ore grade estimation for mineral deposits. � 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
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    Sporadic Peutz-Jeghers Syndrome with Recurrent Intussusception and Malignant Change in Hamartomatous Polyps
    (Springer, 2023) Kumar, Sandeep; Gaba, Shivam; Tewari, Mallika; Jain, Gaurav
    Peutz-Jeghers syndrome (PJS) is a rare inherited autosomal dominant disease characterised by mucocutaneous pigmentation and multiple polyps in the gastrointestinal tract. In up to 25% of cases, there is no family history of PJS (sporadic cases). Acute intestinal intussusception due to multiple polyps is the most common complication of PJS. PJS is associated with cancers of the gastrointestinal tract and in other organs. Adenocarcinoma arising in hamartomatous polyps is heavily debated. A 23-year-old gentleman presented with sporadic PJS with recurrent ileal intussusceptions and multifocal well-differentiated adenocarcinomas arising in the background of hamartomatous polyps following hamartoma-dysplasia-carcinoma sequence, which is herein discussed. The hamartoma-dysplasia-carcinoma sequence is one of the pathways of carcinogenesis within hamartomatous polyps in PJS. � 2022, Association of Surgeons of India.
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    Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies in neuro-intensive care unit patients and associations with outcome (ENIO) trial
    (BioMed Central Ltd, 2023) Wahlster, Sarah; Sharma, Monisha; Taran, Shaurya; Town, James A.; Stevens, Robert D.; Cinotti, Rapha�l; Asehoune, Karim; Pelosi, Paolo; Robba, Chiara; Abback, Pa�r-s�lim; Codorniu, Ana�s; Citerio, Giuseppe; Sala, Vittoria Ludovica; Astuto, Marinella; Tringali, Eleonora; Alampi, Daniela; Rocco, Monica; Maugeri, Jessica Giuseppina; Bellissima, Agrippino; Filippini, Matteo; Lazzeri, Nicoletta; Cortegiani, Andrea; Ippolito, Mariachiara; Battaglini, Denise; Biston, Patrick; Al-Gharyani, Mohamed Fathi; Chabanne, Russell; Astier, L�o; Soyer, Benjamin; Gaugain, Samuel; Zimmerli, Alice; Pietsch, Urs; Filipovic, Miodrag; Brandi, Giovanna; Bicciato, Giulio; Serrano, Ainhoa; Monleon, Berta; van Vliet, Peter; Gerretsen, Benjamin Marcel; Ortiz-Macias, Iris Xochitl; Oto, Jun; Enomoto, Noriya; Matsuda, Tomomichi; Masui, Nobutaka; Gar�on, Pierre; Zarka, Jonathan; Vermeijden, Wytze J.; Cornet, Alexander Daniel; Inurrigarro, Sergio Reyes; Dom�nguez, Rafael Cirino Lara; Bellini, Maria Mercedes; Gomez Haedo, Maria Milagros; Lamot, Laura; Orquera, Jose; Biais, Matthieu; Georges, Delphine; Baronia, Arvind; Miranda-Ackerman, Roberto Carlos; Barbosa-Camacho, Francisco Jos�; Porter, John; Lopez-Morales, Miguel; Geeraerts, Thomas; Compagnon, Baptiste; P�rez-Torres, David; Prol-Silva, Estefan�a; Yahya, Hana Basheer; Khaled, Ala; Ghula, Mohamed; Andrea, Cracchiolo Neville; Daniela, Palma Maria; Deana, Cristian; Vetrugno, Luigi; Chavez, Manuel J. Rivera; Trujillo, Rocio Mendoza; Legros, Vincent; Brochet, Benjamin; Huet, Olivier; Geslain, Marie; van der Jagt, Mathieu; van Steenkiste, Job; Ahmed, Hazem; Coombs, Alexander Edward; Welbourne, Jessie; Velarde Pineda, Ana Alicia; Nubert Castillo, V�ctor Hugo; Azab, Mohammed A.; Azzam, Ahmed Y.; van Meenen, David Michael Paul; Gasca, Gilberto Adrian; Arellano, Alfredo; Galicia-Espinosa, Forttino; Garc�a-Ramos, Jos� Carlos; Yadav, Ghanshyam; Jha, Amarendra Kumar; Robert-Edan, Vincent; Rodie-Talbere, Pierre-Andre; Jain, Gaurav; Panda, Sagarika; Agarwal, Sonika; Deewan, Yashbir; Reza, Syed Tariq; Hossain, Md.Mozaffer; Papadas, Christos; Chantziara, Vasiliki; Sklavou, Chrysanthi; Hourmant, Yannick; Grillot, Nicolas; van der Jagt, Mathieu; Pirracchio, Romain; Akkari, Abdelraouf; Abdelaty, Mohamed; Hashim, Ahmed; Launey, Yoann; Masseret, Elodie; Lasocki, Sigismond; Gergaud, Soizic; Mouclier, Nicolas; Saxena, Sulekha; Agrawal, Avinash; Mishra, Shakti Bedanta; Samal, Samir; Mijangos, Julio Cesar; Ha�nggi, Mattias; Gurjar, Mohan; Schultz, Marcus J.; Kaye, Callum; Godoy, Daniela Agustin; Alvarez, Pablo; Ioakeimidou, Aikaterini; Ueno, Yoshitoyo; Badenes, Rafael; Suei Elbuzidi, Abdurrahmaan Ali; Piagnerelli, Micha�l; Elhadi, Muhammed; Digitale, Jean Catherine; Fong, Nicholas; Cerda, Ricardo Campos; de la Torre Peredo, Norma
    Background: There is insufficient evidence to guide ventilatory targets in acute brain injury (ABI). Recent studies have shown associations between mechanical power (MP) and mortality in critical care populations. We aimed to describe MP in ventilated patients with ABI, and evaluate associations between MP and clinical outcomes. Methods: In this preplanned, secondary analysis of a prospective, multi-center, observational cohort study (ENIO, NCT03400904), we included adult patients with ABI (Glasgow Coma Scale ? 12 before intubation) who required mechanical ventilation (MV) ? 24�h. Using multivariable log binomial regressions, we separately assessed associations between MP on hospital day (HD)1, HD3, HD7 and clinical outcomes: hospital mortality, need for reintubation, tracheostomy placement, and development of acute respiratory distress syndrome (ARDS). Results: We included 1217 patients (mean age 51.2�years [SD 18.1], 66% male, mean body mass index [BMI] 26.3 [SD 5.18]) hospitalized at 62 intensive care units in 18 countries. Hospital mortality was 11% (n = 139), 44% (n = 536) were extubated by HD7 of which 20% (107/536) required reintubation, 28% (n = 340) underwent tracheostomy placement, and 9% (n = 114) developed ARDS. The median MP on HD1, HD3, and HD7 was 11.9�J/min [IQR 9.2�15.1], 13�J/min [IQR 10�17], and 14�J/min [IQR 11�20], respectively. MP was overall higher in patients with ARDS, especially those with higher ARDS severity. After controlling for same-day pressure of arterial oxygen/fraction of inspired oxygen (P/F ratio), BMI, and neurological severity, MP at HD1, HD3, and HD7 was independently associated with hospital mortality, reintubation and tracheostomy placement. The adjusted relative risk (aRR) was greater at higher MP, and strongest for: mortality on HD1 (compared to the HD1 median MP 11.9�J/min, aRR at 17�J/min was 1.22, 95% CI 1.14�1.30) and HD3 (1.38, 95% CI 1.23�1.53), reintubation on HD1 (1.64; 95% CI 1.57�1.72), and tracheostomy on HD7 (1.53; 95%CI 1.18�1.99). MP was associated with the development of moderate-severe ARDS on HD1 (2.07; 95% CI 1.56�2.78) and HD3 (1.76; 95% CI 1.41�2.22). Conclusions: Exposure to high MP during the first week of MV is associated with poor clinical outcomes in ABI, independent of P/F ratio and neurological severity. Potential benefits of optimizing ventilator settings to limit MP warrant further investigation. � 2023, The Author(s).