Browsing by Author "Kumawat R.K."

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    Exploring the genetic implications of demographic dynamics in Jammu and Kashmir using autosomal STRs
    (Springer Science and Business Media Deutschland GmbH, 2024) Mubarik N.; Ganei M.A.; Dixit S.; Kumawat R.K.; Sequeira J.J.; Ahangar N.A.; Kanth S.A.; Dar I.A.; Mushtaq I.; Mohsin M.; Mustak M.S.; Chaubey G.; Hamid S.; Shrivastava P.
    The Union Territory of Jammu and Kashmir has always been a point of contention among India, Pakistan, and China for various reasons. This region has great significance historically due to its geography and ethnic diversity. However, a comprehensive genetic study providing the genetic landscape of Jammu and Kashmir was lacking until now. In this study, we analysed 21 hyper-variable autosomal STR loci of 694 individuals from Jammu and Kashmir and compared them with neighbouring populations to explore the genetic implications of demographic dynamics that have taken place in this region. Our findings suggest that the population of Jammu and Kashmir is a genetic mixture of two major clines, northern and southern, that correspond with the variation in geography, linguistics, and demography of the region. Broadly, the gene flow into the southern cline appears to be in historical times perhaps as a result of the spread of Gurjars, Dogri language and invasions of Mongols. However, the arrival of ancient nomadic tribes into this region may belong to the time depth of the arrival of pastoralist communities in this region. As a future perspective, a comprehensive study including samples from individual tribes will provide fine-scale structure of the gene pool of Jammu and Kashmir. � The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.
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    The maternal genetic history of tribal populations of Chhattisgarh, India
    (Elsevier B.V., 2024) Dixit S.; Shrivastava P.; Jeevan Sequeira J.; Mustak M.S.; Rana M.; Kushwaha P.; Shrivastava D.; Kumawat R.K.; Pratap Singh P.; Tiwary S.K.; Chauhan N.K.; Chaubey G.
    The central region of India boasts a rich tribal heritage and the highest number of tribal populations in the country. Analysing the genetic history of this population can offer valuable insights into various demographic processes that shaped the gene pool of present-day settlers of this region. In this study, we utilize a recently validated Next-generation sequencing (NGS) technique to sequence 24 tribal mitogenomes from the Chhattisgarh population for genetic ancestry and forensic analysis. The identified ancient haplogroups in this population can be traced back to the pre-Last Glacial Maximum (LGM) period. Our Bayesian analysis provides evidence for maternal ancestral expansion following the earliest Out-of-Africa migration, followed by a prolonged steady phase. We identified three basal founding haplogroups, M2, R5, and U2 in the Chhattisgarh region that diversified during the Neolithic period. Indistinct distribution pattern of these haplogroups among tribes and castes suggests that the maternal ancestry of Chhattisgarh population predates any kind of social stratification that exists today in the Indian subcontinent. Furthermore, our analysis suggests that this region remained unaffected by the Last Glacial Maximum. The forensic analysis of the mitogenomes demonstrates a high power of discrimination (0.9256) within the Chhattisgarh population, thus supporting the applicability of mitogenome NGS technology in forensic contexts. � 2024 Elsevier B.V. and Mitochondria Research Society