Browsing by Author "Mahajan A."
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Item Analytical and numerical examinations on the stability investigation of Casson nanofluid flow in a permeable layer controlled by vertical throughflow(Emerald Publishing, 2024) Mohamad A.M.; Yadav D.; Awasthi M.K.; Ragoju R.; Bhattacharyya K.; Mahajan A.Purpose: The purpose of the study is to analytically as well as numerically investigate the weight of throughflow on the onset of Casson nanofluid layer in a permeable matrix. This study examines both the marginal and over stable kind of convective movement in the system. Design/methodology/approach: A double-phase model is used for Casson nanofluid, which integrates the impacts of thermophoresis and Brownian wave, whereas for flow in the porous matrix the altered Darcy model is occupied under the statement that nanoparticle flux is disappear on the boundaries. The resultant eigenvalue problem is resolved analytically as well as numerically with the help of Galerkin process with the Casson nanofluid Rayleigh�Darcy number as the eigenvalue. Findings: The findings revealed that the throughflow factor postpones the arrival of convective flow and reduces the extent of convective cells, whereas the Casson factor, the Casson nanoparticle Rayleigh�Darcy number and the reformed diffusivity ratio promote convective motion and also decrease the extent of convective cells. Originality/value: Controlling the convective movement in heat transfer systems that generate high heat flux is a real mechanical challenge. The proposed framework proved that the use of throughflow is one of the most important ways to control the convective movement in Casson nanofluid. To the best of the authors� knowledge, no inspection has been established in the literature that studies the outcome of throughflow on the Casson nanofluid convective flow in a porous medium layer. However, the convective flow of Casson nanofluid finds many applications in improving heat transmission and energy efficiency in a range of thermal systems, such as the cooling of heat-generating elements in electronic devices, heat exchangers, pharmaceutical practices and hybrid-powered engines, where throughflow can play a significant role in controlling the convective motion. � 2024, Emerald Publishing Limited.Item Comparative Analysis of Radial Forearm Free Flap and Submental Island Flap in Reconstruction of Post-glossectomy Defects of Oral Squamous Cell Carcinoma and Quality of Life Assessment(Springer, 2024) Singh A.K.; Mahajan A.; Anandkumar J.; Sharma N.K.; Durrani F.; Agrawal N.K.; Kumar P.G.N.; Neville J.F.Aim: Reconstruction of tongue defects has always been a challenging aspect of onco-surgery. Although a variety of locoregional and free flaps have been advocated, it still poses a challenge due to its complex function in deglutition and speech articulation. Hence, this study aims at reducing the dilemma of flap selection for better patient outcome. Materials and Methods: Among 16 tongue carcinoma cases, 6 cases were reconstructed using submental island flap (SIF) and 10 using radial forearm free flap (RFFF). These 2 flaps were compared in terms of parameters like intraoperative time, hospital stay, overall survival, pain, cosmesis, and recreation of anatomy, and functions like deglutition and articulation of speech. Patients were followed for oncologic safety and recurrence. Obtained data were statistically analysed using IBM� SPSS�. Result: SIF showed significantly higher activity score (P = 0.001) with reduced flap harvest time (P = 0.014) but showed difficulty in deglutition (P = 0.03) compared to RFFF. It was concluded that in cases of RFFF mobility and functional outcome was superior, but flap harvest time was considerably higher. Overall patient survival rate was better in cases of RFFF in long-term follow-up, but flap survival rate was significantly higher in SIF owing to better vascularity. Conclusion: In highly compromised cases and salvage cases where microvascular flaps are contraindicated, submental flap being a local flap with comparable overall survival rate, better cosmesis hence, serves as a reliable flap for reconstruction of glossectomy defects. � The Association of Oral and Maxillofacial Surgeons of India 2024.Item Hyena bite: A rare intriguing mode of maxillofacial injury, its management, risks involved, scenarios to avoid(Wolters Kluwer Medknow Publications, 2024) Mahajan A.; Jaiswara C.; Dhiman N.K.; Krishnan A.The striped hyena (Hyaena hyaena) is a rarely spotted carnivore in India listed as Near Threatened (red list) by International Union for Conservation of Nature (IUCN) in 2014. Hyena is considered as scavenger but also executes rare opportunistic attacks on humans. In India, reported cases of hyena attack on humans are very rare, because of remote locations of these attacks majority of which go unreported to higher medical centres. This article describes about the circumstances and management of Hyena inflicted maxillofacial injury in North India, which is as per our knowledge first scientifically documented maxillofacial injury caused by Hyena in Indian subcontinent. � 2024 National Journal of Maxillofacial Surgery | Published by Wolters Kluwer - Medknow.Item Novel Tripartite Classification�for Fractures of�Coronoid Process of Mandible: A Retrospective Tertiary Center Study(Springer, 2024) Mahajan A.; Singh A.K.; Sharma N.K.; Bansal V.; Kumar S.; Mani S.; Akram Z.Introduction: Coronoid process of mandible is seldom fractured during maxillofacial trauma. Majority of the cases of coronoid fracture are treated conservatively, but some lead to complications which are often overlooked. At present, the literature on coronoid fractures is inadequate for meta-analysis. Also, there exists no standardized classification in the literature. Hence, the purpose of this study was to analyze the incidence and establish a novel �tripartite� classification. Material and Methods: In this study carried out at level 1 trauma center, all patients with coronoid fracture with or without associated maxillofacial fractures were included. Relevant data were noted from Hospital records and CT scans (computer tomographic scans). These cases were classified according to �tripartite� classification and treated. Data feed was given to IBM� SPSS� statistics (version 21) for analysis. Results: Among 33 coronoid fracture patients, majority (57.57% cases) were from age group of 21�40�years with 82.85% cases attributed to road traffic accidents. 11.43% cases were bilateral, and the rest unilateral cases revealed right-side predilection. Conclusion: Novel tripartite classification allows us to easily categorize and visualize the coronoid fractures. Horizontal types 1 to 3 and vertical types 4 to 6 are in increasing order of incidence, which makes it easy for communication, treatment approach and record maintenance. � The Association of Oral and Maxillofacial Surgeons of India 2024.Item Quality of Life Assessment and Comparative Analysis of Anterolateral Thigh Flap and Pectoralis Major Myo-cutaneous Flap for Reconstruction of Post Excision Defects of Oral Squamous Cell Carcinoma(Springer, 2024) Mahajan A.; Kumar J.A.; Singh A.K.; Sharma N.K.; Durrani F.; Agrawal N.K.; JF N.Present study is a comparative evaluation of the financial impact on choice of flap, clinical results as well as post resection quality of life assessment of cancer patients reconstructed with anterolateral thigh(ALT) flap and pectoralis major myo-cutaneous(PMMC) flap. Ethical clearance was obtained from institutional ethical committee. In this non-randomised, prospective study design among 49 oral squamous cell carcinoma cases, 39 cases were reconstructed using PMMC flap and 10 using ALT flap from year 2020 to 2022. These 2 flaps were compared in terms of parameters like time utilised for reconstruction, hospital stay, overall survival and Washington University Quality of Life index(UW-QOL) for head and neck cancer. Patients were followed regularly for post-operative complications. The University of Washington Quality of Life score (UW-QOL) questionnaire, version 4, was completed at six months post-operatively. Obtained data was statistically analysed using IBM� SPSS?. Washington University Quality of Life index scores and esthetics are better with Antero-lateral thigh flap, with less overall post-operative complications. On the other hand Pectoralis myocutaneous flap has less surgical time and more salvage potential. Despite of Antero-lateral thigh flap having Good Washington University Quality of Life index scores, lesser post-operative complications and better esthetics; scale of developing nations is still tipping towards economical, less time consuming and less technique sensitive Pectoralis major myocutaneous flap. � Association of Otolaryngologists of India 2024.Item Retinoblastoma in Asia: Clinical Presentation and Treatment Outcomes in 2112 Patients from 33 Countries(Elsevier Inc., 2024) Kaliki S.; Vempuluru V.S.; Mohamed A.; Al-Jadiry M.F.; Bowman R.; Chawla B.; Hamid S.A.; Ji X.; Kapelushnik N.; Kebudi R.; Sthapit P.R.; Rojanaporn D.; Sitorus R.S.; Yousef Y.A.; Fabian I.D.; Abdulqader R.A.; Aggarwal P.; Ahmad A.; Akib M.N.R.; Al Mesfer S.A.; Al Ani M.H.; Al-Badri S.A.F.; Angeles Alcasabas A.P.; Al-Dahmash S.A.; Al-Haddad C.; Yahya Al-Hussaini H.H.; Al-Jumaily U.; Alkatan H.M.; Razzaq Mahmood Al-Mafrachi A.A.; Samad Majeed Al-Shaheen A.A.; Al-Shammary E.H.; Amiruddin P.O.; Armytasari I.; Astbury N.J.; Atalay H.T.; Ataseven E.; Atchaneeyasakul L.-O.; Balayeva R.; Bascaran C.; Begimkulova A.S.; Bhaduri A.; Bhat S.; Bhattacharyya A.; Blum S.; Buaboonnam J.; Burton M.J.; Caspi S.; Chaudhry S.; Chen W.; Chuluunbat T.; Dangboon W.; Das A.; Das P.; Das S.; Du Y.; Dudeja G.; Eka Sutyawan I.W.; Fadoo Z.; Faranoush M.; Foster A.; Frenkel S.; Ghassemi F.; Gomel N.; Gunasekera D.S.; G�nd�z A.K.; Gupta H.; Gupta S.; Gupta V.; Hamzah N.; Hasanreisoglu M.; Hassan S.; Haydar H.A.; Hongeng S.; Hussein Al-Janabi A.N.; Islamov Z.; Janjua T.A.; Jeeva I.; Jo D.H.; Kantar M.; Keomisy J.; Khan Z.J.; Khaqan H.A.; Khetan V.; Khodabande A.; Kim J.H.; Kiratli H.; Ko� I.; Kulvichit K.; Kuntorini M.W.; Li C.; Li K.; Limbu B.; Liu C.; Lutfi D.; Mahajan A.; Maitra P.; Makimbetov E.K.; Maktabi A.M.Y.; Manzhuova L.; Masud S.; Mehrvar A.; Menon V.; John V Mercado G.; Chandra Mishra D.K.; Mohammad M.T.; Mudaliar S.S.; Mushtaq A.; Nair A.G.; Natarajan S.; Nency Y.M.; Neroev V.; Nuruddin M.; Pagarra H.; Palanivelu M.S.; Papyan R.; Pe'er J.; Polyakov V.; Qadir A.O.; Qayyum S.; Qian J.; Quah B.; Rahman A.; Rajkarnikar P.; Ramanjulu R.; Rashid R.; Roy S.R.; Saab R.H.; Saakyan S.; Sabhan A.H.; Saiju R.; Sayalith P.; Sedaghat A.; Seth R.; Shakoor S.A.; Sharma M.K.; Siddiqui S.N.; Singh U.; Singha P.; Soebagjo H.D.; Sultana S.; Sun X.; Supriyadi E.; Surukrattanaskul S.; Suzuki S.; Tan D.; Tang J.; Tashvighi M.; Teh K.H.; Tehuteru E.S.; Thawaba A.D.M.; Toledano H.; Le Trang D.; Tripathy D.; Tuncer S.; Unal E.; Ushakova T.L.; Usmanov R.; Verma N.; Victor A.A.; Vishnevskia-Dai V.; Wang Y.-Z.; Wangtiraumnuay N.; Riono W.P.; Wiwatwongwana A.; Wiwatwongwana D.; Wong E.S.; Wongwai P.; Wu S.-Q.; Xiang D.; Xiao Y.; Xu B.; Xue K.; Yam J.C.; Yang H.; Yaqub M.A.; Yarovaya V.A.; Yarovoy A.A.; Ye H.; Yuliawati P.; Zhang Y.; Zia N.; Zondervan M.Purpose: To describe the clinical presentation and treatment outcomes of children who received a diagnosis of retinoblastoma in 2017 throughout Asia. Design: Multinational, prospective study including treatment-na�ve patients in Asia who received a diagnosis of retinoblastoma in 2017 and were followed up thereafter. Participants: A total of 2112 patients (2797 eyes) from 96 retinoblastoma treatment centers in 33 Asian countries. Interventions: Chemotherapy, radiotherapy, enucleation, and orbital exenteration. Main Outcome Measures: Enucleation and death. Results: Within the cohort, 1021 patients (48%) were from South Asia (SA), 503 patients (24%) were from East Asia (EA), 310 patients (15%) were from Southeast Asia (SEA), 218 patients (10%) were from West Asia (WA), and 60 patients (3%) were from Central Asia (CA). Mean age at presentation was 27 months (median, 23 months; range, < 1�261 months). The cohort included 1195 male patients (57%) and 917 female patients (43%). The most common presenting symptoms were leukocoria (72%) and strabismus (13%). Using the American Joint Committee on Cancer Staging Manual, Eighth Edition, classification, tumors were staged as cT1 (n = 441 [16%]), cT2 (n = 951 [34%]), cT3 (n = 1136 [41%]), cT4 (n = 267 [10%]), N1 (n = 48 [2%]), and M1 (n = 129 [6%]) at presentation. Retinoblastoma was treated with intravenous chemotherapy in 1450 eyes (52%) and 857 eyes (31%) underwent primary enucleation. Three-year Kaplan-Meier estimates for enucleation and death were 33% and 13% for CA, 18% and 4% for EA, 27% and 15% for SA, 32% and 22% for SEA, and 20% and 11% for WA (P < 0.0001 and P < 0.0001), respectively. Conclusions: At the conclusion of this study, significant heterogeneity was found in treatment outcomes of retinoblastoma among the regions of Asia. East Asia displayed better outcomes with higher rates of globe and life salvage, whereas Southeast Asia showed poorer outcomes compared with the rest of Asia. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. � 2023 American Academy of Ophthalmology
